Skip to main content

Advertisement

Log in

Active Wearable Compression with Shape Memory Actuators for Treating Chronic Edema

  • Technical Article
  • Published:
Shape Memory and Superelasticity Aims and scope Submit manuscript

Abstract

Chronic edema can occur from impairment of the lymphatic, arterial, and venous systems. It can be a lifelong condition where self-care and treatment are necessary to manage the progressive worsening of the disease, which can lead to increased risk for infection, cellulitis, ulceration, wound, and amputation. At-home treatment options for this chronic debilitating disease are very limited. Existing PCDs have been around for several decades and have several major disadvantages. SMA embodied in a novel NPCD format allows for opportunity to address some of these disadvantages. Comparison of the two types of compression devices SMA-based NPCD and traditional PCD are evaluated and discussed in this study. Pressures were compared on both silicon and human subjects and visualization of applied pressure was also analyzed. Both devices provide comparable pressure range though PCD has higher variability in terms of uniformity of pressure applied. NPCD using SMA offers new treatment opportunity for patients with chronic edema at home in an entirely mobile and wearable platform.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

References

  1. Rockson SG (2001) Lymphedema. Am J Med 110:288–295

    Article  CAS  Google Scholar 

  2. Szuba A, Rockson SG (1997) Lymphedema: anatomy, physiology and pathogenesis. Vasc Med 2:321–326

    Article  CAS  Google Scholar 

  3. Underlying incidence data are from the SEER 9 areas http://seer.cancer.gov/registries/terms.html2020.

  4. Carvalho AL, Nishimoto IN, Califano JA, Kowalski LP (2005) Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer 114:806–816

    Article  CAS  Google Scholar 

  5. Duygu Yildiz E, Bakar Y, Keser I (2022) What do lymphedema patients expect from a treatment and what do they achieve? A descriptive study. J Vasc Nursing 40(1):59–65. https://doi.org/10.1016/j.jvn.2022.01.002

    Article  Google Scholar 

  6. Jeffs E, Wiseman T (2013) Randomised controlled trial to determine the benefit of daily home-based exercise in addition to self-care in the management of breast cancer-related lymphoedema: a feasibility study. Support Care Cancer 21(4):1013–1023. https://doi.org/10.1007/s00520-012-1621-6

    Article  Google Scholar 

  7. Noone A-M, Cronin KA, Altekruse SF, Howlader N, Lewis DR, Petkov VI, Penberthy L (2017) Cancer incidence and survival trends by subtype using data from the surveillance epidemiology and end results program, 1992–2013. Cancer Epidemiol Prevent Biomark 26:632–641

    Article  Google Scholar 

  8. Fu MR (2014) Breast cancer-related lymphedema: Symptoms, diagnosis, risk reduction, and management. World J Clin Oncol 5:241

    Article  Google Scholar 

  9. Fu MR, Rosedale M (2009) Breast cancer survivors’ experiences of lymphedema-related symptoms. J Pain Symptom Manage 38:849–859

    Article  Google Scholar 

  10. International Society of Lymphology (2003) The diagnosis and treatment of peripheral lymphedema. Consensus document of the International Society of Lymphology. Lymphology 36:84–91

    Google Scholar 

  11. Armer JM, Radina ME, Porock D, Culbertson SD (2003) Predicting breast cancer-related lymphedema using self-reported symptoms. Nurs Res 52:370–379

    Article  Google Scholar 

  12. Mayrovitz HN (2009) The standard of care for lymphedema: current concepts and physiological considerations. Lymphat Res Biol 7:101–108

    Article  Google Scholar 

  13. Lawenda BD, Mondry TE, Johnstone PA (2009) Lymphedema: a primer on the identification and management of a chronic condition in oncologic treatment. A Cancer J Clin 59:8–24

    Article  Google Scholar 

  14. International Lymphoedema Framework (2006) Best practice for the management of lymphoedema. International Consensus. London: MEP Ltd 3–52

  15. Cormier J, Feldman J, Askew R, Beck M, Bernas M, Francis K, Fu M, Lasinski B, Rodrick J, Stewart B (2010) ALFP to update the best practice document. J Lymphoedema 5:68–71

    Google Scholar 

  16. Lurie F, Malgor RD, Carman T, Dean SM, Iafrati MD, Khilnani NM, Labropoulos N, Maldonado TS, Mortimer P, O’Donnell TF Jr, Raffetto JD, Rockson SG, Gasparis AP (2022) The American Venous Forum, American Vein and lymphatic society and the society for vascular medicine expert opinion consensus on lymphedema diagnosis and treatment. Phlebology 37(4):252–266. https://doi.org/10.1177/02683555211053532

    Article  Google Scholar 

  17. Ridner SH, Murphy B, Deng J, Kidd N, Galford E, Bonner C, Bond SM, Dietrich MS (2012) A randomized clinical trial comparing advanced pneumatic truncal, chest, and arm treatment to arm treatment only in self-care of arm lymphedema. Breast Cancer Res Treat 131:147–158

    Article  CAS  Google Scholar 

  18. Karaca-Mandic P, Hirsch AT, Rockson SG, Ridner SH (2015) The cutaneous, net clinical, and health economic benefits of advanced pneumatic compression devices in patients with lymphedema. JAMA Dermatol 151:1187–1193

    Article  Google Scholar 

  19. Adams KE, Rasmussen JC, Darne C, Tan I-C, Aldrich MB, Marshall MV, Fife CE, Maus EA, Smith LA, Guilloid R (2010) Direct evidence of lymphatic function improvement after advanced pneumatic compression device treatment of lymphedema. Biomed Opt Express 1:114–125

    Article  Google Scholar 

  20. Wilburn O, Wilburn P, Rockson SG (2006) A pilot, prospective evaluation of a novel alternative for maintenance therapy of breast cancer-associated lymphedema. BMC Cancer 6:1–10

    Article  Google Scholar 

  21. Fife CE, Davey S, Maus EA, Guilliod R, Mayrovitz HN (2012) A randomized controlled trial comparing two types of pneumatic compression for breast cancer-related lymphedema treatment in the home. Support Care Cancer 20:3279–3286

    Article  Google Scholar 

  22. Hammond T (2009) Reduction of complications and associated costs with Flexitouch® therapy for lymphedema. The Open Rehabilitation Journal 2:54–57

    Article  Google Scholar 

  23. Ridner SH, McMahon E, Dietrich MS, Hoy S (2008) Home-based lymphema treatment in patients with cancer-related lymphedema or non cancer-related lymphedema. Oncol Nurs Forum 35(4):671–680

    Article  Google Scholar 

  24. Blumberg SN, Berland T, Rockman C, Mussa F, Brooks A, Cayne N, Maldonado T (2016) Pneumatic compression improves quality of life in patients with lower-extremity lymphedema. Ann Vasc Surg 30:40–44

    Article  Google Scholar 

  25. Brayton KM, Hirsch AT, Patricia J, Cheville A, Karaca-Mandic P, Rockson SG (2014) Lymphedema prevalence and treatment benefits in cancer: impact of a therapeutic intervention on health outcomes and costs. PLoS ONE 9:114597

    Article  Google Scholar 

  26. Mayrovitz HN (2007) Interface pressures produced by two different types of lymphedema therapy devices. Phys Ther 87(10):1379–1388. https://doi.org/10.2522/ptj.20060386

    Article  Google Scholar 

  27. Boris, M.; Weindorf, S. (1997) Persistence of lymphedema reduction after noninvasive complex lymphedema therapy. Cancer 11

  28. Rockson SG, Karaca-Mandic P, Skoracki R, Hock K, Nguyen M, Shadduck K, Gingerich P, Campione E, Leifer A, Armer J (2022) Clinical evaluation of a novel wearable compression technology in the treatment of Lymphedema, an open-label controlled study. Lymphat Res Biol 22(2):125–132

    Article  Google Scholar 

  29. Rockson, S. G., Whitworth, P. W., Cooper, A., Kania, S., Karnofel, H., Nguyen M., Shadduck, K., Gingerich, P., Armer, J., (2022) Safety and Effectiveness of a Novel Non-Pneumatic Active Compression Device for Treating Breast Cancer-Related Lymphedema, a Multi-center Randomized, Crossover Trial. Journal of Vascular Surgery

Download references

Acknowledgments

This study was funded by Koya Medical, Inc.

Conflict of interest

Ms. Rodrick and Dr. Hettrick serve as advisors to Koya Medical, Inc. Mr. Pamplin, Mr. Baldwin, and Dr. Doraiswamy are employed by Koya Medical, Inc.

Author information

Authors and Affiliations

Authors

Consortia

Corresponding author

Correspondence to Anand Doraiswamy.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This invited article is part of a special topical focus in the journal Shape Memory and Superelasticity on Cardiovascular Nitinol Medical Devices. The issue was organized by Dr. Srinidhi Nagaraja, G.RAU, Inc. and Dr. Harshad M. Paranjape, Confluent Medical Technologies, Inc.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pamplin, J., Baldwin, J., Rodrick, J. et al. Active Wearable Compression with Shape Memory Actuators for Treating Chronic Edema. Shap. Mem. Superelasticity 8, 142–149 (2022). https://doi.org/10.1007/s40830-022-00379-w

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40830-022-00379-w

Keywords

Navigation