Impact of Ixekizumab on Work Productivity in Patients with Ankylosing Spondylitis: Results from the COAST-V and COAST-W Trials at 52 Weeks

Table 2 Work Productivity and Activity Index for Spondyloarthritis scores at baseline for biologic disease-modifying anti-rheumatic drug-naïve patients (COAST-V study) across treatment arms

Work productivity and activity measures	Treatment arms
Work productivity and activity measures	PBO (N = 87)	ADA (N = 90)	IXE Q4W (N = 81)	IXE Q2W (N = 83)
Absenteeism^a
Nx	57	71	61	57
Mean (SD)	7.2 (14.8)	13.6 (27.2)	8.0 (20.4)	14.1 (27.9)
Presenteeism^a
Nx	57	66	59	53
Mean (SD)	61.4 (19.5)	53.2 (21.9)	57.1 (21.3)	54.9 (21.5)
Overall work impairment^a
Nx	57	66	59	53
Mean (SD)	63.2 (20.3)	55.0 (23.3)	58.7 (21.8)	57.4 (22.8)
Activity impairment
Nx	87	90	81	83
Mean (SD)	62.4 (20.5)	58.2 (20.5)	58.8 (18.1)	61.0 (20.7)

ADA 40 mg adalimumab every 2 weeks, IXE Q2W 80 mg ixekizumab every 2 weeks, IXE Q4W 80 mg ixekizumab every 4 weeks, N number of patients in the treatment group, Nx number of patients in the analysis subgroup, PBO placebo
^aAbsenteeism, presenteeism, and overall work impairment were measured in patients reporting part- or full-time work