Facile Synthesis of Nanosilver-Incorporated Titanium Nanotube for Antibacterial Surfaces
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The battle against postoperative infection in orthopedic surgery calls for the development of surfaces with antibacterial activity on the implant side of the bacterial biofilm. Incorporation of nanosilver into titanium nanotube surfaces offers a potential solution. This study presents a novel single-step anodization approach to incorporating nanosilver particles within and among anodized titanium nanotubes on implant surfaces using a new hybrid electrolyte. The amount of nanosilver deposited on the titanium nanotubes was analyzed by varying the silver concentration in the hybrid electrolyte. Successful fabrication of titanium nanotubes by anodization of foils, rods and thermal plasma-sprayed surfaces of Ti6Al4V, and simultaneous nanosilver deposition was quantified by field emission scanning electron microscopy, transmission electron microscopy and X-ray energy-dispersive spectroscopy. Upon post-anodization heat treatment, the amorphous to anatase conversion of these structures was confirmed using X-ray diffraction analysis. This study presents a simple single-step fabrication of antibacterial titanium nanotube surfaces allowing controlled nanosilver deposition needed to avoid unintended cytotoxicity.
KeywordsOrthopedic Implant infection Antimicrobial TiO2 nanotube, surface anodization Silver
This work performed under the M-TRAC program was supported by Grant Case-48161 of the Twenty-First Century Jobs Trust Fund received through the Michigan Strategic Fund from the State of Michigan. The M-TRAC program is funded by the Michigan Strategic Fund with program oversight by the Michigan Economic Development Corporation. The work was also supported by the Multi-Scale Technologies Institute at Michigan Technological University.
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