Skip to main content

Advertisement

Log in

Rehabilitation of Individuals with Limb Loss due to Trauma

  • Amputations: From Injury To Rehabilitation (R Zafonte, Section Editor)
  • Published:
Current Trauma Reports Aims and scope Submit manuscript

Abstract

Purpose of the Review

To provide a comprehensive overview of care and rehabilitation of those with traumatic limb loss, from preoperative to lifelong care.

Recent Findings

Comprehensive care including peer support and monitoring for the development of secondary conditions which compound disability is essential after traumatic amputation. Conditions that commonly develop after traumatic limb loss include heterotopic ossification, intact limb knee osteoarthritis, low back pain, and reduction in cardiopulmonary reserve.

Summary

Optimal care for people after traumatic limb loss requires a multidisciplinary team to provide perioperative and lifelong care. In addition to ensuring optimal rehabilitation based on the individual’s vocational and avocational goals, current function, concomitant injuries, and amputation level, their psychological recovery must not be overlooked. To optimize quality of life and independence, lifelong follow-up with a physiatrist is essential to care for complications and secondary conditions, as well as to promote an active lifestyle.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Dillingham TR, Pezzin LE, MacKenzie EJ. Incidence, acute care length of stay, and discharge to rehabilitation of traumatic amputee patients: an epidemiologic study. Arch Phys Med Rehabil. 1998;79(3):279–87.

    Article  CAS  Google Scholar 

  2. Higgins TF, Klatt JB, Beals TC. Lower extremity assessment project (LEAP)--the best available evidence on limb-threatening lower extremity trauma. Orthop Clin North Am. 2010;41(2):233–9. https://doi.org/10.1016/j.ocl.2009.12.006.

    Article  PubMed  Google Scholar 

  3. Doukas WC, Hayda RA, Frisch HM, Andersen RC, Mazurek MT, Ficke JR, et al. The military extremity trauma amputation/limb salvage (METALS) study: outcomes of amputation versus limb salvage following major lower-extremity trauma. J Bone Joint Surg Am. 2013;95(2):138–45. https://doi.org/10.2106/JBJS.K.00734.

    Article  PubMed  Google Scholar 

  4. Krueger CA, Rivera JC, Tennent DJ, Sheean AJ, Stinner DJ, Wenke JC. Late amputation may not reduce complications or improve mental health in combat-related, lower extremity limb salvage patients. Injury. 2015;46(8):1527–32. https://doi.org/10.1016/j.injury.2015.05.015.

    Article  PubMed  Google Scholar 

  5. Rauh MJ, Aralis HJ, Melcer T, Macera CA, Sessoms P, Bartlett J, et al. Effect of traumatic brain injury among U.S. servicemembers with amputation. J Rehabil Res Dev. 2013;50(2):161–72.

    Article  Google Scholar 

  6. Ficke JR. Transtibial amputation: surgical management. In: Krajbich JI, Pinzur MS, Potter BK, Stevens PM, editors. Atlas of amputations and limb deficiencies: surgical, prosthetic, and rehabilitation principles. 4th ed. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2016. p. 485–91.

    Google Scholar 

  7. Tintle SM, Keeling JJ, Shawen SB, Forsberg JA, Potter BK. Traumatic and trauma-related amputations: part I: general principles and lower-extremity amputations. J Bone Joint Surg Am. 2010;92(17):2852–68. https://doi.org/10.2106/JBJS.J.00257.

    Article  PubMed  Google Scholar 

  8. Gottschalk F. Transfemoral amputation: surgical management. In: Krajbich JI, Pinzur MS, Potter BK, Stevens PM, editors. Atlas of amputations and limb deficiencies: surgical, prosthetic, and rehabilitation principles. 4th ed. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2016. p. 525–35.

    Google Scholar 

  9. Behr J, Friedly J, Molton I, Morgenroth D, Jensen MP, Smith DG. Pain and pain-related interference in adults with lower-limb amputation: comparison of knee-disarticulation, transtibial, and transfemoral surgical sites. J Rehabil Res Dev. 2009;46(7):963–72.

    Article  Google Scholar 

  10. Nanos GP III. Wrist disarticulation and Transradial amputation: surgical management. In: Krajbich JI, Pinzur MS, Potter BK, Stevens PM, editors. Atlas of amputations and limb deficiencies: surgical, prosthetic, and rehabilitation principles. 4th ed. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2016. p. 221–31.

    Google Scholar 

  11. Cho MS. Elbow disarticulation and Transhumeral amputation: surgical management. In: Krajbich JI, Pinzur MS, Potter BK, Stevens PM, editors. Atlas of amputations and limb deficiencies: surgical, prosthetic, and rehabilitation principles. 4th ed. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2016. p. 249–55.

    Google Scholar 

  12. • Reichmann JP, Bartman KR. An integrative review of peer support for patients undergoing major limb amputation. J Vasc Nurs. 2018;36(1):34–9. https://doi.org/10.1016/j.jvn.2017.10.002This review article, while drawing from limited published evidence, supports the integration of pre- and post-operative peer visitors for people with major limb amputation.

    Article  PubMed  Google Scholar 

  13. Krueger CA, Wenke JC. Initial injury severity and social factors determine ability to deploy after combat-related amputation. Injury. 2014;45(8):1231–5. https://doi.org/10.1016/j.injury.2014.02.008.

    Article  PubMed  Google Scholar 

  14. Webster JB, Poorman CE, Cifu DX. Guest editorial: Department of Veterans Affairs Amputations System of care:5 years of accomplishments and outcomes. J Rehabil Res Dev. 2014;51(4):vii–xvi. https://doi.org/10.1682/JRRD.2014.01.0024.

    Article  PubMed  Google Scholar 

  15. Butler K, Bowen C, Hughes AM, Torah R, Ayala I, Tudor J, et al. A systematic review of the key factors affecting tissue viability and rehabilitation outcomes of the residual limb in lower extremity traumatic amputees. J Tissue Viability. 2014;23(3):81–93. https://doi.org/10.1016/j.jtv.2014.08.002.

    Article  PubMed  Google Scholar 

  16. Meroni R, Beghi E, Beghi M, Brambilla G, Cerri C, Perin C, et al. Psychiatric disorders in patients suffering from an acute cerebrovascular accident or traumatic injury, and their effects on rehabilitation: an observational study. Eur J Phys Rehabil Med. 2013;49(1):31–9.

    CAS  PubMed  Google Scholar 

  17. Mckechnie PS, John A. Anxiety and depression following traumatic limb amputation: a systematic review. Injury. 2014;45(12):1859–66. https://doi.org/10.1016/j.injury.2014.09.015.

    Article  CAS  PubMed  Google Scholar 

  18. Bhatnagar V, Richard E, Melcer T, Walker J, Galarneau M. Lower-limb amputation and effect of posttraumatic stress disorder on Department of Veterans Affairs outpatient cost trends. J Rehabil Res Dev. 2015;52(7):827–38. https://doi.org/10.1682/JRRD.2014.11.0288.

    Article  PubMed  Google Scholar 

  19. Foote CE, Kinnon JM, Robbins C, Pessagno R, Portner MD. Long-term health and quality of life experiences of Vietnam veterans with combat-related limb loss. Qual Life Res. 2015;24(12):2853–61. https://doi.org/10.1007/s11136-015-1029-0.

    Article  PubMed  Google Scholar 

  20. Wegener ST, Mackenzie EJ, Ephraim P, Ehde D, Williams R. Self-management improves outcomes in persons with limb loss. Arch Phys Med Rehabil. 2009;90(3):373–80. https://doi.org/10.1016/j.apmr.2008.08.222.

    Article  PubMed  Google Scholar 

  21. Yazicioglu K, Yavuz F, Goktepe AS, Tan AK. Influence of adapted sports on quality of life and life satisfaction in sport participants and non-sport participants with physical disabilities. Disabil Health J. 2012;5(4):249–53. https://doi.org/10.1016/j.dhjo.2012.05.003.

    Article  PubMed  Google Scholar 

  22. Laferrier JZ, Teodorski E, Cooper RA. Investigation of the impact of sports, exercise, and recreation participation on psychosocial outcomes in a population of veterans with disabilities: a cross-sectional study. Am J Phys Med Rehabil. 2015;94(12):1026–34. https://doi.org/10.1097/PHM.0000000000000263.

    Article  PubMed  Google Scholar 

  23. Wetterhahn KA, Hanson C, Levy CE. Effect of participation in physical activity on body image of amputees. Am J Phys Med Rehabil. 2002;81(3):194–201.

    Article  Google Scholar 

  24. Biddis EA, Chau TT. Upper limb prosthesis use and abandonment: a survey of the last 25 years. Prosthetics Orthot Int. 2007;31(3):236–57. https://doi.org/10.1080/03093640600994581.

    Article  Google Scholar 

  25. Malone JM, Fleming LL, Roberson J, Whitesides TE, Leal JM, Poole JU, et al. Immediate, early, and late postsurgical management of upper-limb amputation. J Rehabil Res Dev. 1984;21(1):33–41.

    CAS  PubMed  Google Scholar 

  26. Gaine WJ, Smart C, Bransby-Zachary M. Upper limb traumatic amputees. Review of prosthetic use. J Hand Surg Br. 1997;22(1):73–6.

    Article  CAS  Google Scholar 

  27. • Keszler MS, Heckman JT, Kaufman GE, Morgenroth DC. Advances in prosthetics and rehabilitation of individuals with limb loss. Phys Med Rehabil Clin N Am. 2019;30(2):423–37. https://doi.org/10.1016/j.pmr.2018.12.013This review provides the most current update on advances in the field of prosthetics and amputation rehabilitation.

    Article  PubMed  Google Scholar 

  28. Knowlton LM, Gosney JE, Chackungal S, Altschuler E, Black L, Burkle FM, et al. Consensus statements regarding the multidisciplinary care of limb amputation patients in disasters or humanitarian emergencies: report of the 2011 humanitarian action summit surgical working group on amputations following disasters or conflict. Prehosp Disaster Med. 2011;26(6):438–48. https://doi.org/10.1017/S1049023X12000076.

    Article  PubMed  Google Scholar 

  29. Eikermann M, Velmahos G, Abbara S, Huang PL, Fagan SP, Hirschberg RE, et al. Case records of the Massachusetts General Hospital. Case 11-2014. A man with traumatic injuries after a bomb explosion at the Boston Marathon. N Engl J Med. 2014;370(15):1441–51. https://doi.org/10.1056/NEJMcpc1314240.

    Article  CAS  PubMed  Google Scholar 

  30. Hick JL, Hanfling D, Evans B, Greenberg D, Alson R, McKinney S, et al. Health and medical response to active shooter and bombing events. Washington, DC: National Academy of Medicine; 2016.

    Book  Google Scholar 

  31. Gates JD, Arabian S, Biddinger P, Blansfield J, Burke P, Chung S, et al. The initial response to the Boston marathon bombing: lessons learned to prepare for the next disaster. Ann Surg. 2014;260(6):960–6. https://doi.org/10.1097/SLA.0000000000000914.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Crandell DM. 49th W. J. Zeiter lecture, the specialty of hope: how physiatry made Boston strong. PM R. 2018;10(5):533–7. https://doi.org/10.1016/j.pmrj.2018.03.010.

    Article  PubMed  Google Scholar 

  33. Edwards DS, Kuhn KM, Potter BK, Forsberg JA. Heterotopic ossification: a review of current understanding, treatment, and future. J Orthop Trauma. 2016;30(Suppl 3):S27–30. https://doi.org/10.1097/BOT.0000000000000666.

    Article  PubMed  Google Scholar 

  34. • Cannon JW, Hofmann LJ, Glasgow SC, Potter BK, Rodriguez CJ, Cancio LC, et al. Dismounted complex blast injuries: a comprehensive review of the modern combat experience. J Am Coll Surg. 2016;223(4):652–64.e8. https://doi.org/10.1016/j.jamcollsurg.2016.07.009Review of the dismounted complex blast injuries, which have increased due to recent conflicts, describing the outcomes, challenging treatment, and complications of these injuries.

    Article  PubMed  Google Scholar 

  35. Shehab D, Elgazzar AH, Collier BD. Heterotopic ossification. J Nucl Med. 2002;43(3):346–53.

    PubMed  Google Scholar 

  36. Pavey GJ, Polfer EM, Nappo KE, Tintle SM, Forsberg JA, Potter BK. What risk factors predict recurrence of heterotopic ossification after excision in combat-related amputations? Clin Orthop Relat Res. 2015;473(9):2814–24. https://doi.org/10.1007/s11999-015-4266-1.

    Article  PubMed  PubMed Central  Google Scholar 

  37. • Farrokhi S, Mazzone B, Eskridge S, Shannon K, Hill OT. Incidence of overuse musculoskeletal injuries in military service members with traumatic lower limb amputation. Archives of Physical Medicine and Rehabilitation. 2018;99:348–54. https://doi.org/10.1016/j.apmr.2017.10.010This study examined the rate of upper and lower limb overuse injuries, as well as low back pain, after traumatic unilateral and bilateral lower extremity amputations.

    Article  PubMed  Google Scholar 

  38. Morgenroth DC, Gellhorn AC, Suri P. Osteoarthritis in the disabled population: a mechanical perspective. PM R. 2012;4(5 Suppl):S20–7. https://doi.org/10.1016/j.pmrj.2012.01.003.

    Article  PubMed  Google Scholar 

  39. Struyf PA, van Heugten CM, Hitters MW, Smeets RJ. The prevalence of osteoarthritis of the intact hip and knee among traumatic leg amputees. Arch Phys Med Rehabil. 2009;90(3):440–6. https://doi.org/10.1016/j.apmr.2008.08.220.

    Article  PubMed  Google Scholar 

  40. Norvell DC, Czerniecki JM, Reiber GE, Maynard C, Pecoraro JA, Weiss NS. The prevalence of knee pain and symptomatic knee osteoarthritis among veteran traumatic amputees and nonamputees. Arch Phys Med Rehabil. 2005;86(3):487–93. https://doi.org/10.1016/j.apmr.2004.04.034.

    Article  PubMed  Google Scholar 

  41. Farrokhi S, Mazzone B, Yoder A, Grant K, Wyatt M. A narrative review of the prevalence and risk factors associated with development of knee osteoarthritis after traumatic unilateral lower limb amputation. Mil Med. 2016;181(S4):38–44. https://doi.org/10.7205/MILMED-D-15-00510.

    Article  PubMed  Google Scholar 

  42. Pruziner AL, Werner KM, Copple TJ, Hendershot BD, Wolf EJ. Does intact limb loading differ in servicemembers with traumatic lower limb loss? Clin Orthop Relat Res. 2014;472(10):3068–75. https://doi.org/10.1007/s11999-014-3663-1.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Morgenroth DC, Segal AD, Zelik KE, Czerniecki JM, Klute GK, Adamczyk PG, et al. The effect of prosthetic foot push-off on mechanical loading associated with knee osteoarthritis in lower extremity amputees. Gait Posture. 2011;34(4):502–7. https://doi.org/10.1016/j.gaitpost.2011.07.001.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Ehde DM, Smith DG, Czerniecki JM, Campbell KM, Malchow DM, Robinson LR. Back pain as a secondary disability in persons with lower limb amputations. Arch Phys Med Rehabil. 2001;82(6):731–4. https://doi.org/10.1053/apmr.2001.21962.

    Article  CAS  PubMed  Google Scholar 

  45. Friel K, Domholdt E, Smith DG. Physical and functional measures related to low back pain in individuals with lower-limb amputation: an exploratory pilot study. J Rehabil Res Dev. 2005;42(2):155–66.

    Article  Google Scholar 

  46. Morgenroth DC, Orendurff MS, Shakir A, Segal A, Shofer J, Czerniecki JM. The relationship between lumbar spine kinematics during gait and low-back pain in transfemoral amputees. Am J Phys Med Rehabil. 2010;89(8):635–43. https://doi.org/10.1097/PHM.0b013e3181e71d90.

    Article  PubMed  Google Scholar 

  47. • Highsmith MJ, Goff LM, Lewandowski AL, Farrokhi S, Hendershot BD, Hill OT, et al. Low back pain in persons with lower extremity amputation: a systematic review of the literature. Spine J. 2019;19(3):552–63. https://doi.org/10.1016/j.spinee.2018.08.011Systematic review exploring different factors that potentially increase the risk of low back pain in people with lower limb amputations.

    Article  PubMed  Google Scholar 

  48. Buckley C, Buckley S. Do you really lose cardiopulmonary reserve after major amputation? JICC. 2016;6S:138–9.

    Google Scholar 

  49. Kurdibaylo SF. Cardiorespiratory status and movement capabilities in adults with limb amputation. J Rehabil Res Dev. 1994;31(3):222–35.

    CAS  PubMed  Google Scholar 

  50. Modan M, Peles E, Halkin H, Nitzan H, Azaria M, Gitel S, et al. Increased cardiovascular disease mortality rates in traumatic lower limb amputees. Am J Cardiol. 1998;82(10):1242–7. https://doi.org/10.1016/s0002-9149(98)00601-8.

    Article  CAS  PubMed  Google Scholar 

  51. Peles E, Akselrod S, Goldstein DS, Nitzan H, Azaria M, Almog S, et al. Insulin resistance and autonomic function in traumatic lower limb amputees. Clin Auton Res. 1995;5(5):279–88.

    Article  CAS  Google Scholar 

  52. Naschitz JE, Lenger R. Why traumatic leg amputees are at increased risk for cardiovascular diseases. QJM. 2008;101(4):251–9. https://doi.org/10.1093/qjmed/hcm131.

    Article  CAS  PubMed  Google Scholar 

  53. Vollmar JF, Paes E, Pauschinger P, Henze E, Friesch A. Aortic aneurysms as late sequelae of above-knee amputation. Lancet. 1989;2(8667):834–5. https://doi.org/10.1016/s0140-6736(89)92999-1.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mary S. Keszler.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Amputations: From Injury To Rehabilitation

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Keszler, M.S., Crandell, D.M. & Morgenroth, D.C. Rehabilitation of Individuals with Limb Loss due to Trauma. Curr Trauma Rep 6, 96–104 (2020). https://doi.org/10.1007/s40719-020-00193-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40719-020-00193-8

Keywords

Navigation