Skip to main content

Advertisement

Log in

Sustained low-efficiency dialysis with regional citrate anticoagulation is a suitable therapeutic option for refractory hypermagnesemia in critically ill patients with AKI

  • Lessons for the Clinical Nephrologist
  • Published:
Journal of Nephrology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Data availability

The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

References

  1. Aal-Hamad AH, Al-Alawi AM, Kashoub MS, Falhammar H (2023) Hypermagnesemia in Clinical Practice. Medicina (Kaunas) 59(7):1190. https://doi.org/10.3390/medicina59071190

    Article  PubMed  Google Scholar 

  2. Pistolesi V, Morabito S, Pota V et al (2023) Regional citrate anticoagulation (RCA) in critically ill patients undergoing renal replacement therapy (RRT): expert opinion from the SIAARTI-SIN joint commission. J Anesth Analg Crit Care 3(1):7. https://doi.org/10.1186/s44158-023-00091-w

    Article  PubMed  PubMed Central  Google Scholar 

  3. de Baaij JH, Hoenderop JG, Bindels RJ (2015) Magnesium in man: implications for health and disease. Physiol Rev 95(1):1–46. https://doi.org/10.1152/physrev.00012.2014

    Article  CAS  PubMed  Google Scholar 

  4. Van Laecke S (2019) Hypomagnesemia and hypermagnesemia. Acta Clin Belg 74(1):41–47. https://doi.org/10.1080/17843286.2018.1516173

    Article  PubMed  Google Scholar 

  5. Di Mario F, Regolisti G, Greco P et al (2021) Prevention of hypomagnesemia in critically ill patients with acute kidney injury on continuous kidney replacement therapy: the role of early supplementation and close monitoring. J Nephrol 34(4):1271–1279. https://doi.org/10.1007/s40620-020-00864-4

    Article  CAS  PubMed  Google Scholar 

  6. Sethi S, Mangat G, Soundararajan A et al (2023) Archetypal sustained low-efficiency daily diafiltration (SLEDD-f) for critically ill patients requiring kidney replacement therapy: towards an adequate therapy. J Nephrol. https://doi.org/10.1007/s40620-023-01665-1

    Article  PubMed  Google Scholar 

  7. Fiaccadori E, Regolisti G, Cademartiri C et al (2013) Efficacy and safety of a citrate-based protocol for sustained low-efficiency dialysis in AKI using standard dialysis equipment. Clin J Am Soc Nephrol 8(10):1670–1678. https://doi.org/10.2215/CJN.00510113

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Walker P, Parnell S, Dillon RC (2020) Epsom salt ingestion leading to severe hypermagnesemia necessitating dialysis. J Emerg Med 58(5):767–770. https://doi.org/10.1016/j.jemermed.2020.04.023

    Article  PubMed  Google Scholar 

  9. Bokhari SR, Siriki R, Teran FJ et al (2018) Fatal hypermagnesemia due to laxative use. Am JMed Sci 355(4):390–395. https://doi.org/10.1016/j.amjms.2017.08.013

    Article  Google Scholar 

Download references

Acknowledgements

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Francesca Di Mario.

Ethics declarations

Conflict of interest

None declared. The authors did not receive support from any organization for the submitted work.

Informed consent

For this type of study formal consent is not required.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Menegazzo, B., Regolisti, G., Greco, P. et al. Sustained low-efficiency dialysis with regional citrate anticoagulation is a suitable therapeutic option for refractory hypermagnesemia in critically ill patients with AKI. J Nephrol (2024). https://doi.org/10.1007/s40620-023-01837-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s40620-023-01837-z

Keywords

Navigation