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The assessment of cognitive function in older adult patients with chronic kidney disease: an integrative review

  • Mary Hannan
  • Alana Steffen
  • Lauretta Quinn
  • Eileen G. Collins
  • Shane A. Phillips
  • Ulf G. Bronas
Review
  • 63 Downloads

Abstract

Introduction

Chronic kidney disease (CKD) is a common chronic condition in older adults that is associated with cognitive decline. However, the exact prevalence of cognitive impairment in older adults with CKD is unclear likely due to the variety of methods utilized to assess cognitive function. The purpose of this integrative review is to determine how cognitive function is most frequently assessed in older adult patients with CKD.

Methods

Five electronic databases were searched to explore relevant literature related to cognitive function assessment in older adult patients with CKD. Inclusion and exclusion criteria were created to focus the search to the assessment of cognitive function with standardized cognitive tests in older adults with CKD, not on renal replacement therapy.

Results

Through the search methods, 36 articles were found that fulfilled the purpose of the review. There were 36 different types of cognitive tests utilized in the included articles, with each study utilizing between one and 12 tests. The most commonly utilized cognitive test was the Mini Mental State Exam (MMSE), followed by tests of digit symbol substitution and verbal fluency. The most commonly assessed aspect of cognitive function was global cognition.

Discussion

The assessment of cognitive function in older adults with CKD with standardized tests is completed in various ways. Unfortunately, the common methods of assessment of cognitive function may not be fully examining the domains of impairment commonly found in older adults with CKD. Further research is needed to identify the ideal cognitive test to best assess older adults with CKD for cognitive impairment.

Keywords

Older adult Cognitive impairment Kidney disease 

Notes

Acknowledgements

Mary Hannan is a Robert Wood Johnson Foundation Future of Nursing Scholar. Ulf G. Bronas is supported by the Midwest Roybal Center for Health Promotion and Translation.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical statement

Human subjects were not utilized in this research. For this type of study formal consent is not required. This article does not contain any studies with human participants or animals performed by any of the authors.

Supplementary material

40620_2018_494_MOESM1_ESM.xlsx (19 kb)
Supplementary material 1 (XLSX 19 KB)

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Copyright information

© Italian Society of Nephrology 2018

Authors and Affiliations

  1. 1.Department of Biobehavioral Health Science, College of NursingUniversity of Illinois at ChicagoChicagoUSA
  2. 2.Department of Health Systems Science, College of NursingUniversity of Illinois at ChicagoChicagoUSA
  3. 3.Department of Physical Therapy, College of Allied Health ScienceUniversity of Illinois at ChicagoChicagoUSA

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