Journal of Nephrology

, Volume 29, Issue 2, pp 169–174 | Cite as

Acute kidney injury among ST elevation myocardial infarction patients treated by primary percutaneous coronary intervention: a multifactorial entity

Review

Abstract

Acute kidney injury is a frequent complication among ST segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI), and is associated with adverse outcomes. While contrast nephropathy is considered the most important reason for worsening of renal function, recent data have suggested the role of other important factors among this specific patient population. In the present review, we examine the various factors leading to renal impairment in STEMI patients and place the findings in the context of this specific patient population in the era of primary PCI. These factors include contrast nephropathy, time to coronary reperfusion, cardiac pump function and hemodynamics as well as various inflammatory and metabolic markers.

Keywords

Acute kidney injury ST elevation myocardial infarction Percutaneous coronary intervention Contrast induced nephropathy 

Notes

Compliance with ethical standards

Conflict of interest

None on the part of any author.

Ethical standard

The research did not involve human participants and/or animals.

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Copyright information

© Italian Society of Nephrology 2016

Authors and Affiliations

  1. 1.Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the Sackler Faculty of MedicineTel-Aviv UniversityTel AvivIsrael

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