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Journal of Nephrology

, Volume 29, Issue 2, pp 163–168 | Cite as

Transplantation of kidneys with tumors

  • Giovanni M. Frascà
  • Antonia D’Errico
  • Deborah Malvi
  • Camillo Porta
  • Laura Cosmai
  • Matteo Santoni
  • Silvio Sandrini
  • Chiara Salviani
  • Maurizio Gallieni
  • Emilio Balestra
Review

Abstract

The shortage of donors in the face of the increasing number of patients wait-listed for renal transplantation has prompted several strategies including the use of kidneys with a tumor, whether found by chance on harvesting from a deceased donor or intentionally removed from a living donor and transplanted after excision of the lesion. Current evidence suggests that a solitary well-differentiated renal cell carcinoma, Fuhrman nuclear grade I-II, less than 1 cm in diameter and resected before grafting may be considered at minimal risk of recurrence in the recipient who, however, should be informed of the possible risk and consent to receive such a graft.

Keywords

Renal cancer Renal transplantation Kidney donation Tumor transmission Safety of donation 

Notes

Acknowledgments

This paper was promoted by the “Onco-Nephrology Working Group” coordinated by Maurizio Gallieni under the auspices of the Italian Society of Nephrology (SIN), chaired by Giovanbattista Capasso and the Italian Association of Medical Oncology (AIOM), chaired by Stefano Cascinu.

Compliance with ethical standards

Funding

No author received any fund for the paper.

Conflict of interest

The authors declare that they have no conflict of interest.

Research involving human participants and/or animals

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

For this type of study formal consent is not required.

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Copyright information

© Italian Society of Nephrology 2015

Authors and Affiliations

  • Giovanni M. Frascà
    • 1
  • Antonia D’Errico
    • 2
  • Deborah Malvi
    • 2
  • Camillo Porta
    • 3
  • Laura Cosmai
    • 4
  • Matteo Santoni
    • 5
  • Silvio Sandrini
    • 6
  • Chiara Salviani
    • 6
  • Maurizio Gallieni
    • 7
    • 8
  • Emilio Balestra
    • 1
  1. 1.Nephrology, Dialysis and Renal Transplantation UnitOspedali RiunitiAnconaItaly
  2. 2.“F. Addarii” Institute of Oncology and Transplantation PathologyBologna UniversityBolognaItaly
  3. 3.Medical OncologyI.R.C.C.S. San Matteo University Hospital FoundationPaviaItaly
  4. 4.Nephrology and Dialysis UnitIstituti Ospitalieri CremonaCremonaItaly
  5. 5.Clinica di Oncologia Medica-Università Politecnica delle MarcheAnconaItaly
  6. 6.U.O. NefrologiaSpedali Civili di BresciaBresciaItaly
  7. 7.Nephrology and Dialysis UnitSan Carlo Borromeo HospitalMilanItaly
  8. 8.Department of Biomedical and Clinical Sciences “Luigi Sacco”University of MilanoMilanItaly

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