Transplantation of kidneys with tumors
The shortage of donors in the face of the increasing number of patients wait-listed for renal transplantation has prompted several strategies including the use of kidneys with a tumor, whether found by chance on harvesting from a deceased donor or intentionally removed from a living donor and transplanted after excision of the lesion. Current evidence suggests that a solitary well-differentiated renal cell carcinoma, Fuhrman nuclear grade I-II, less than 1 cm in diameter and resected before grafting may be considered at minimal risk of recurrence in the recipient who, however, should be informed of the possible risk and consent to receive such a graft.
KeywordsRenal cancer Renal transplantation Kidney donation Tumor transmission Safety of donation
This paper was promoted by the “Onco-Nephrology Working Group” coordinated by Maurizio Gallieni under the auspices of the Italian Society of Nephrology (SIN), chaired by Giovanbattista Capasso and the Italian Association of Medical Oncology (AIOM), chaired by Stefano Cascinu.
Compliance with ethical standards
No author received any fund for the paper.
Conflict of interest
The authors declare that they have no conflict of interest.
Research involving human participants and/or animals
This article does not contain any studies with human participants or animals performed by any of the authors.
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