Sommario
La sempre più vasta disponibilità e il maggior potere diagnostico delle indagini ultrasonografiche nel rivelare i segni delle numerose comorbidità e complicanze dell’acromegalia, anche quando non ancora diagnosticata, possono contribuire a ridurre il frequente ritardo diagnostico. La cardiomiopatia acromegalica può essere precocemente rivelata dall’ecocardiogramma, come l’aterosclerosi, dallo studio dell’intima. La visceromegalia, il gozzo multinodulare, la rigidità dei parenchimi, steatosi epatica, colelitiasi, polipi della cistifellea, cisti renali, nefrolitiasi e ovaio policistico, sono alcune delle alterazioni evidenti all’ecografia. L’ecografia muscoloscheletrica e neuronale può evidenziare aumento dello spessore della cartilagine articolare, ridotta mineralizzazione ossea e l’aumento del diametro delle fibre nervose. La conoscenza di tali evidenze ecografiche anche da parte dei numerosi specialisti non endocrinologi potrebbe contribuire alla riduzione del ritardo diagnostico nell’acromegalia.
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Gli autori Matteo Parolin, Francesca Dassie, Roberto Vettor e Pietro Maffei dichiarano di non avere conflitti di interesse.
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Parolin, M., Dassie, F., Vettor, R. et al. Acromegalia ed ecografia: uno sguardo nel profondo. L'Endocrinologo 22, 179–186 (2021). https://doi.org/10.1007/s40619-021-00859-8
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DOI: https://doi.org/10.1007/s40619-021-00859-8