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Gli adenomi ipofisari in gravidanza

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La gravidanza influisce su morfologia e funzione ipofisarie e tali modificazioni possono rendere complessa non solo la diagnosi di patologie ipofisarie di nuova insorgenza, ma anche il follow-up e la gestione di adenomi ipofisari, secernenti e non, diagnosticati prima della gravidanza. I dati attualmente disponibili su andamento, gestione e esito della gravidanza sono prevalentemente concentrati sulle pazienti con adenomi ipofisari PRL e GH-secernenti. La gestione di queste pazienti durante la gravidanza dipende da tipologia, dimensioni ed estensione dell’adenoma e andrebbe preferibilmente affidata a Centri dedicati alla diagnosi e cura delle patologie ipofisarie. In questa Rassegna si descriveranno in breve sia le modificazioni morfo-funzionali della ghiandola ipofisaria in corso di gravidanza sia le modalità di gestione per ciascuna tipologia di adenoma ipofisario.

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Correspondence to Andrea Lania.

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Conflitti di interesse

Gli autori Nazarena Betella, Walter Vena, Emilia Biamonte, Elisabetta Lavezzi e Andrea Lania dichiarano di non avere conflitti di interesse.

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Lo studio presentato in questo articolo non ha richiesto sperimentazione umana.

Studio sugli animali

Gli autori di questo articolo non hanno eseguito studi sugli animali.

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Proposto da Alessandro Peri.

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Springer Nature rimane neutrale in riguardo alle rivendicazioni giurisdizionali nelle mappe pubblicate e nelle affiliazioni istituzionali.

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Betella, N., Vena, W., Biamonte, E. et al. Gli adenomi ipofisari in gravidanza. L'Endocrinologo 21, 246–251 (2020). https://doi.org/10.1007/s40619-020-00765-5

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