Sommario
In età pediatrica e prepuberale le cellule del Sertoli sono attivamente proliferanti e metabolicamente attive. I livelli sierici di ormone anti-mülleriano (AMH) e di inibina B, entrambi prodotti dalle cellule del Sertoli, rappresentano dei marcatori della funzione testicolare particolarmente utili. Già in età pediatrica e prepuberale, infatti, essi presentano livelli alterati in numerose patologie andrologiche. In età pediatrica e prepuberale, AMH e inibina B, insieme all’ecometria testicolare, potrebbero essere utilizzati per la diagnosi precoce delle disfunzioni testicolari.
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Gli autori Rosita A. Condorelli, Rossella Cannarella, Aldo E. Calogero e Sandro La Vignera dichiarano di non avere conflitti di interesse.
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Condorelli, R.A., Cannarella, R., Calogero, A.E. et al. Valutazione della funzione testicolare in età pediatrica e prepuberale. L'Endocrinologo 19, 136–141 (2018). https://doi.org/10.1007/s40619-018-0446-z
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DOI: https://doi.org/10.1007/s40619-018-0446-z