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Complicanze croniche del diabete: i due sessi a confronto

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Sommario

Il numero di evidenze sulle differenze di genere nell’ambito del diabete e delle sue complicanze è in crescente aumento. Numerosi fattori, biologici, ambientali e psicosociali, sono potenzialmente coinvolti, ma i meccanismi fisiopatologici alla base sono ancora in parte sconosciuti. La comparsa del diabete sembrerebbe determinare una perdita dell’effetto protettivo degli estrogeni, predisponendo maggiormente il sesso femminile allo sviluppo di complicanze, soprattutto cardiovascolari.

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Bibliografia

  1. Kautzky-Willer A, Harreiter J, Pacini G (2016) Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus. Endocr Rev 37(3):278–316

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Russo G, Baggio G, Teobaldi I et al (2017) Differenze di genere nelle complicanze croniche del diabete di tipo 2. http://www.siditalia.it/clinica/linee-guida-societari/send/80-linee-guida-documenti-societari/3282-focus-on-sid-differenze-di-genere-nelle-complicanze-croniche-del-diabete-di-tipo-2. Accessed on July 27, 2018

  3. Yusuf S, Hawken S, Ounpuu S et al. (2004) INTERHEART study investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 364(9438):937–952

    Article  PubMed  Google Scholar 

  4. Peters SA, Huxley RR, Woodward M (2014) Diabetes as risk factor for incident coronary heart disease in women compared with men: a systematic review and meta-analysis of 64 cohorts including 858,507 individuals and 28,203 coronary events. Diabetologia 57:1542–1551

    Article  PubMed  Google Scholar 

  5. Peters SA, Huxley RR, Woodward M (2014) Diabetes as a risk factor for stroke in women compared with men: a systematic review and meta-analysis of 64 cohorts, including 775,385 individuals and 12,539 strokes. Lancet 383:1973–1980

    Article  PubMed  Google Scholar 

  6. Prospective Studies Collaboration Asia Pacific Cohort Studies Collaboration (2018) Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980 793 adults from 68 prospective studies. Lancet Diabetes Endocrinol 6(7):538–546

    Article  Google Scholar 

  7. Hecking M, Bieber BA, Ethier J et al. (2014) Sex-specific differences in hemodialysis prevalence and practices and the male-to-female mortality rate: the dialysis outcomes and practice patterns study (DOPPS). PLoS Med 11(10):e1001750

    Article  PubMed  PubMed Central  Google Scholar 

  8. Penno G, Solini A, Bonore E et al. (2011) Renal Insufficiency And Cardiovascular Events (RIACE) study group. Clinical significance of nonalbuminuric renal impairment in type 2 diabetes. J Hypertens 29:1802–1809

    Article  CAS  PubMed  Google Scholar 

  9. Ozawa GY, Bearse MA Jr, Adams AJ (2015) Male-female differences in diabetic retinopathy? Curr Eye Res 40(2):234–246

    Article  CAS  PubMed  Google Scholar 

  10. Schmidl D, Schmetterer L, Garhöfer G, Popa-Cherecheanu A (2015) Gender differences in ocular blood flow. Curr Eye Res 40(2):201–212

    Article  CAS  PubMed  Google Scholar 

  11. Peek ME (2011) Gender differences in diabetes-related lower extremity amputations. Clin Orthop Relat Res 469:1951–1955

    Article  Google Scholar 

  12. Crawford F, Cezard G, Chappell FM et al. (2015) A systematic review and individual patient data meta-analysis of prognostic factors for foot ulceration in people with diabetes: the international research collaboration for the prediction of diabetic foot ulcerations (PODUS). Health Technol Assess 19(57):1–210

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Dipartimento di Medicina Sperimentale, Sezione di Fisiopatologia Medica, Endocrinologia e Scienza dell’Alimentazione, Sapienza Università di Roma, Roma, Italia

    Susanna Morano, Tiziana Filardi & Federica Tavaglione

Authors
  1. Susanna Morano
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  2. Tiziana Filardi
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  3. Federica Tavaglione
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Corresponding author

Correspondence to Susanna Morano.

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Conflitto di interessi

Gli autori Susanna Morano, Tiziana Filardi e Federica Tavaglione dichiarano di non avere conflitti di interesse.

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Lo studio presentato in questo articolo non ha richiesto sperimentazione umana.

Studi su animali

Gli autori di questo articolo non hanno eseguito studi su animali.

Additional information

Proposto da Elisa Giannetta.

Materiale elettronico supplementare

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Morano, S., Filardi, T. & Tavaglione, F. Complicanze croniche del diabete: i due sessi a confronto. L'Endocrinologo 19, 297–300 (2018). https://doi.org/10.1007/s40619-018-00507-8

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  • DOI: https://doi.org/10.1007/s40619-018-00507-8

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