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NAFLD, diabete tipo 2, rischio cardiovascolare?

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La steatosi epatica non alcolica (NAFLD) è attualmente l’epatopatia cronica più comune nella pratica clinica. La prevalenza della NAFLD è assai elevata nel diabete tipo 2 (T2D), essendo presente in oltre il 60–70% di tali pazienti. In questa breve rassegna discuteremo le evidenze clinico-epidemiologiche che suggeriscono una significativa associazione tra NAFLD e aumentato rischio di complicanze cardiovascolari nel T2D e i possibili meccanismi fisiopatologici che spiegano tale associazione.

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Correspondence to Giovanni Targher.

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Conflitto di interesse

Gli autori Alessandro Mantovani, Riccardo Rigolon, Teresa Turino, Isabella Pichiri e Giovanni Targher dichiarano di non avere conflitti di interesse.

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Lo studio presentato in questo articolo non ha richiesto sperimentazione umana.

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Gli autori di questo articolo non hanno eseguito studi su animali.

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Proposto da Riccardo Bonadonna.

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Mantovani, A., Rigolon, R., Turino, T. et al. NAFLD, diabete tipo 2, rischio cardiovascolare?. L'Endocrinologo 19, 255–259 (2018). https://doi.org/10.1007/s40619-018-00478-w

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