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Sindrome di Klinefelter e autoimmunità

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La sindrome di Klinefelter (KS) è caratterizzata da disgenesia testicolare ed associata ad uno o più cromosomi X sovranumerari. Oltre al quadro di ipogonadismo ipergonadotropo, ad oggi, nei pazienti KS è stata dimostrata una maggiore predisposizione verso processi autoimmuni caratteristici dell’artrite reumatoide, polimiosite e dermatomiosite, lupus eritematoso sistemico, sclerosi sistemica, alterazioni miste del connettivo (MCTD), diabete di tipo 1 e tiroidite di Hashimoto.

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Bibliografia

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Authors and Affiliations

  1. Centro Regionale per le Malattie rare endocrino-andrologiche, Policlinico Umberto I, Sezione di Fisiopatologia Medica, Scienza dell’Alimentazione ed Endocrinologia, Dipartimento di Medicina Sperimentale, Sapienza Università di Roma, Roma, Italia

    Antonio F. Radicioni & Francesca Panimolle

Authors
  1. Antonio F. Radicioni
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  2. Francesca Panimolle
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Corresponding author

Correspondence to Antonio F. Radicioni.

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Conflitti di interesse

Gli autori Antonio F. Radicioni e Francesca Panimolle dichiarano di non avere conflitti di interesse.

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Lo studio presentato in questo articolo non ha richiesto sperimentazione umana.

Studi sugli animali

Gli autori di questo articolo non hanno eseguito studi sugli animali.

Additional information

Proposto da Donatella Paoli.

Materiale elettronico supplementare

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Radicioni, A.F., Panimolle, F. Sindrome di Klinefelter e autoimmunità. L'Endocrinologo 18, 159–164 (2017). https://doi.org/10.1007/s40619-017-0342-y

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  • DOI: https://doi.org/10.1007/s40619-017-0342-y

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