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Testosterone e apparato cardiovascolare

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Sommario

Le malattie cardiovascolari (CVD) rappresentano le più importanti cause di morbilità e mortalità nei paesi industrializzati. Recentemente è emersa una correlazione tra deficit androgenico e CVD, come anche un’associazione con aumentati livelli di glucosio, con un assetto lipidico pro-aterogenico, un pattern citochinico pro-infiammatorio, nonché con un incremento dello spessore miointimale, e con la presenza di disfunzione endoteliale. La terapia sostitutiva con testosterone in presenza di comorbidità dimostra un ottimo profilo di sicurezza.

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Correspondence to Antonio Aversa.

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Conflitto di interesse

Antonio Aversa ha ricevuto compensi da Bayerhealthcare; Emmanuele A. Jannini ha ricevuto compensi da Bayerhealthcare e Besins. Gli autori Davide Francomano, Andrea M. Isidori, Andrea Fabbri e Andrea Lenzi dichiarano di non avere conflitti di interesse.

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Lo studio presentato in questo articolo non ha richiesto sperimentazione umana.

Studi sugli animali

Gli autori di questo articolo non hanno eseguito studi sugli animali.

Additional information

Proposta da F. Trimarchi and E.A. Jannini.

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Aversa, A., Francomano, D., Isidori, A.M. et al. Testosterone e apparato cardiovascolare. L'Endocrinologo 15, 203–206 (2014). https://doi.org/10.1007/s40619-014-0068-z

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