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Vitamin D: not all is bad

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References

  1. Reid IR (2014) Effects of vitamin D supplements on bone density. J Endocrinol Invest. doi:10.1007/s40618-014-0127-0

    PubMed  Google Scholar 

  2. Lieben L, Masuyama R, Torrekens S, Van Looveren R, Schrooten J, Baatsen P, Lafage-Proust MH, Dresselaers T, Feng JQ, Bonewald LF, Meyer MB, Pike JW, Bouillon R, Carmeliet G (2012) Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. J Clin Invest 122:1803–1815

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  3. Yamamoto Y, Yoshizawa T, Fukuda T, Shirode-Fukuda Y, Yu T, Sekine K, Sato T, Kawano H, Aihara K, Nakamichi Y, Watanabe T, Shindo M, Inoue K, Inoue E, Tsuji N, Hoshino M, Karsenty G, Metzger D, Chambon P, Kato S, Imai Y (2013) Vitamin D receptor in osteoblasts is a negative regulator of bone mass control. Endocrinology 154:1008–1020

    Article  PubMed  CAS  Google Scholar 

  4. Romagnoli E, Pepe J, Piemonte S, Cipriani C, Minisola S (2013) Management of endocrine disease: value and limitations of assessing vitamin D nutritional status and advised levels of vitamin D supplementation. Eur J Endocrinol 169:R59–R69

    Article  PubMed  CAS  Google Scholar 

  5. Romagnoli E, Carnevale V, Biondi P, Minisola S (2014) Vitamin D supplementation: when and how? J Endocrinol Invest 37:603–607

    Article  Google Scholar 

  6. Heaney RP (2011) Assessing vitamin D status. Curr Opin Clin Nutr Metab Care 14:440–444

    Article  PubMed  CAS  Google Scholar 

  7. Ebeling PR, Wark JD, Yeung S, Poon C, Salehi N, Nicholson GC, Kotowicz MA (2001) Effects of calcitriolor calcium on bone mineral density, bone turnover, and fractures in men with primary osteoporosis: a two-year randomized, double blind, double placebo study. J Clin Endocrinol Metab 86:4098–4103

    Article  PubMed  CAS  Google Scholar 

  8. Smith H, Anderson F, Raphael H, Maslin P, Crozier S, Cooper C (2007) Effect of annual intramuscular vitamin D on fracture risk in elderly men and women-a population-based, randomized, double-blind, placebo-controlled trial. Rheumatology 46:1815–1822

    Google Scholar 

  9. Sanders KM, Stuart AL, Williamson EJ, Simpson JA, Kotowicz MA, Young D, Nicholson GC (2010) Annual high-dose oral vitamin D and falls and fractures in older women: a randomized control trial. JAMA 303:1815–1822

    Article  PubMed  CAS  Google Scholar 

  10. Minisola S, Colangelo L, Cilli M, Cipriani C, Pepe J, Romagnoli E (2013) Intermittent high doses of vitamin D: a need for further studies? Calcif Tissue Int 92:487–488

    Article  PubMed  CAS  Google Scholar 

  11. Rossini M, Alberti V, Flor L, Masiero L, Giannini S, Gatti D, Adami S (2004) Effect of oral vitamin D2 yearly bolus on hip fracture risk in elderly women: a community primary prevention study. Aging Clin Exp Res 16:432–436

    Article  PubMed  CAS  Google Scholar 

  12. Lauretani F, Frondini C, Davoli ML, Martini E, Pellicciotti F, Zagatti A, Giordano A, Zurlo A, Pioli G (2012) Vitamin D supplementation is required to normalize serum level of 25OH-vitamin D in older adults: an observational study of 974 hip fracture inpatients. J Endocrinol Invest 35:921–924

    PubMed  CAS  Google Scholar 

  13. Xiang F, Jiang J, Li H, Yuan J, Yang R, Wang Q, Zhang Y (2013) High prevalence of vitamin D insufficiency in pregnant women working indoors and residing in Guiyang, China. J Endocrinol Invest 36:503–507

    PubMed  CAS  Google Scholar 

  14. Bilinski K, Boyages S (2013) The vitamin D paradox: bone density testing in females aged 45 to 74 did not increase over a ten-year period despite a marked increase in testing for vitamin D. J Endocrinol Invest 36:914–922

    PubMed  CAS  Google Scholar 

  15. Carter GD, Phinney KW (2014) Assessing vitamin D status: time for a rethink? Clin Chem 60:809–811

    Article  PubMed  CAS  Google Scholar 

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Conflict of interest

Salvatore Minisola, Cristiana Cipriani, Sara Piemonte, Alfredo Scillitani, Jessica Pepe, declare they have no conflict of interest.

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Authors and Affiliations

  1. Department of Internal Medicine and Medical Disciplines, “Sapienza” Rome University, Via del Policlinico 155, 00161, Rome, Italy

    S. Minisola, C. Cipriani, S. Piemonte & J. Pepe

  2. Unit of Endocrinology, “Casa Sollievo della Sofferenza” Hospital, IRCCS, San Giovanni Rotondo (FG), Italy

    A. Scillitani

Authors
  1. S. Minisola
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  2. C. Cipriani
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  3. S. Piemonte
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  4. A. Scillitani
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  5. J. Pepe
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Corresponding author

Correspondence to S. Minisola.

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Minisola, S., Cipriani, C., Piemonte, S. et al. Vitamin D: not all is bad. J Endocrinol Invest 37, 1015–1016 (2014). https://doi.org/10.1007/s40618-014-0151-0

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  • DOI: https://doi.org/10.1007/s40618-014-0151-0

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