Skip to main content

Table 1 Impacts of arsenic on cognition in children and adults

From: The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review

Cognitive assessment Exposure Age Finding Reference
Intelligence (IQ) Low and High Children ↓verbal IQ
↓total IQ
Calderon et al. 2001 [42]
Medium Children ↓total IQ Rosado et al. 2007 [14]
Low and High Children (5-15 y.o.) ↓total IQ Von Ehrenstein et al. 2007 [16]
Low Children (9-10 y.o.) ↓total IQ Wasserman et al. 2004 [17]
Low Children (6 y.o. and 10 y.o.) ↓total IQ Wasserman et al. 2007 [30]
Low and Medium Children (5 y.o.) ↓total IQ (females)
↓verbal IQ (females)
Hamandani et al. 2011 [26•]
Cognitive skills (reading, writing, vocabulary, math) Medium Children (6-7 y.o.) ↓capacity in figure design, vocabulary, letter sequencing Rosado et al. 2007 [14]
Medium Children (6-7 y.o.) ↓capacity in vocabulary Roy et al. 2011 [15]
Low and High Children (5-15 y.o.) ↓capacity in vocabulary, language Von Ehrenstein et al. 2007 [16]
Low Adults ↓capacity in executive function, mental acuity, verbal skills O’Bryant et al. 2011 [43••]
Visual perception Medium Children (6-7 y.o.) ↓capacity in visual search Rosado et al. 2007 [14]
Low and High Children (5-15 y.o.) ↓capacity in picture completion, object assembly Von Ehrenstein et al. 2007 [16]
Mental health Medium Children ↑risk for ADHD Roy et al. 2011 [15]
Low Adults ↑incidence of depression Zierold et al. 2004 [53]
Medium Adults ↑symptoms of anxiety Dang et al. 2008 [50], Dang et al. 2009
Low → High Adults ↓quality of life and mental health Syed et al. 2012 [47]
High Adults ↑symptoms of altered mental health Fujino et al. 2004 [51]
Low → High Adults ↑insomnia ↓general health Guo et al. 2007 [49]
Low → High Adults ↑risk of psychiatric disorder, depression, anxiety Sen et al. 2012 [52]
  1. Exposure
  2. Low: less than 50 μg/L (ppb) urinary arsenic or water arsenic
  3. Medium: between 50 μg/L (ppb) and 100 μg/L (ppb) urinary or water arsenic
  4. High: more than 100 μg/L (ppb) urinary arsenic or water arsenic