Skip to main content
Log in

Two Cases of Fetal Lower Urinary Tract Obstruction (LUTO) with Similar Presentations Before But Contrasting Outcomes After Fetoscopic Laser Fulguration of Posterior Urethral Valves

  • Fetal Procedures
  • Published:
Journal of Fetal Medicine

Abstract

Posterior urethral valves (PUV) are the commonest cause of lower urinary tract obstruction detected during the antenatal and immediate postnatal period in male fetuses. Treatment options for PUV during the antenatal period include percutaneous vesico-amniotic shunt, fetoscopic fulguration of the valve and open fetal cystostomy. We report two cases of fetal cystoscopic laser valvotomy with fairly similar pre-operative profiles but contrasting postnatal outcomes, which re-iterates the fact that case selection in such cases continues to be a challenge. These are the first case reports on fetoscopic laser valvotomy in India to the best of our knowledge.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Robyn R, Benachi A, Daikha-Dahmane F, etal,. Correlation between ultrasound and anatomical findings in fetuses with lower urinary tract obstruction in the first half of pregnancy. Ultrasound Obstet Gynecol. 2005;25:478–82.

    Article  Google Scholar 

  2. Abbott JF, Levine D, Wapner R. Posterior urethral valves: inaccuracy of prenatal diagnosis. Fetal DiagnTher. 1998;13:179–83.

    Article  CAS  Google Scholar 

  3. Anumba DO, Scott JE, Plant ND, et al. Diagnosis and outcome of fetal lower urinary tract obstruction in the northern region of England. Prenat Diagn. 2005;25:7–13.

    Article  Google Scholar 

  4. Merrill DC, Weiner CP. Urinary tract obstruction. In: Fisk NM, Moise KJ Jr, editors. Fetal therapy: invasive and transplacental. Cambridge: Cambridge University Press; 1997. p. 273–86.

    Google Scholar 

  5. Johnson MP, Freedman AL. Fetal uropathy. Curr Opin Obstet Gynecol. 1999;11:185–94.

    Article  CAS  Google Scholar 

  6. Elder JS, Duckett JW, Synder HM. Intervention for obstructive uropathy: Has it been effective? Lancet. 1987;2:1007–10.

    Article  CAS  Google Scholar 

  7. Quintero RA, Hume R, Smith C, et al. Percutaneous fetal cystoscopy and endoscopic fulguration of posterior urethral valves. Am J Obstet Gynecol. 1995;6:66.

    Google Scholar 

  8. Morris RK, Quinlan-Jones E, Kilby MD, Khan KS. Systematic review of accuracy of fetal urine analysis to predict poor postnatal renal function in cases of congenital urinary tract obstruction. Prenat Diagn. 2007;27:900–11.

    Article  CAS  Google Scholar 

  9. Haeri S. Fetal Lower Urinary Tract Obstruction (LUTO): a practical review for providers. Matern Health Neonatol Perinatol. 2015;1:26. https://doi.org/10.1186/s40748-015-0026-1.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Quintero RA, Shukla AR, Homsy YL, Bukkapatnam R. Successful in utero endoscopic ablation of posterior urethral valves: a new dimension in fetal urology. Urology. 2000;55:77.

    Article  Google Scholar 

  11. Quintero RA, Morales WJ, Allen MH, Bornick PW, Johnson P. Fetal hydrolaparoscopy and endoscopic cystotomy in complicated cases of lower urinary tract obstruction. Am J Obstet Gynecol. 2000;183:324–30.

    Article  CAS  Google Scholar 

  12. Quintero RA, Homsy Y, Bornick PW, Allen M, Johnson PK. In-utero treatment of fetal bladder-outlet obstruction by a ureterocele. Lancet. 2001;357:1947–8.

    Article  CAS  Google Scholar 

  13. Agarwal SK, Fisk NM. In utero therapy for lower urinary tract obstruction. Prenat Diagn. 2001;21:970–6.

    Article  CAS  Google Scholar 

  14. Schmidt S, Hofmann R, Tekesin I, et al. Operative fetoscopical management of intrauterine obstructive uropathia by urethral stent. J Perinat Med. 2003;31:313–6.

    Article  Google Scholar 

  15. Welsh A, Agarwal S, Kumar S, et al. Fetal cystoscopy in the management of fetal obstructive uropathy: experience in a single European centre. Prenat Diagn. 2003;23:1033–41.

    Article  Google Scholar 

  16. Hofmann R, Becker T, Meyer-Wittkopf M, et al. Fetoscopic placement of a transurethral stent for intrauterine obstructive uropathy. J Urol. 2004;171:384–6.

    Article  Google Scholar 

  17. Clifton MS, Harrison MR, Ball R, Lee H. Fetoscopic transuterine release of posterior urethral valves: a new technique. Fetal Diagn Ther. 2007;23:81–6.

    Google Scholar 

  18. Ruano R, Pimenta EJ, Duarte S, Zugaib M. Four-dimensional ultrasonographic imaging of fetal lower urinary tract obstruction and guidance of percutaneous cystoscopy. Ultrasound Obstet Gynecol. 2009;33:250–2.

    Article  CAS  Google Scholar 

  19. Ruano R, Duarte S, Bunduki V, Giron AM, Srougi M, Zugaib M. Fetal cystoscopy for severe lower urinary tract obstruction—initial experience of a single center. Prenat Diagn. 2010;30(1):30–9.

    Article  Google Scholar 

  20. Ruano R, Yoshisaki CT, Salustiano EM, Giron AM, Srougi M, Zugaib M. Early fetal cystoscopy for first-trimester severe megacystis. Ultrasound Obstet Gynecol. 2011;37(6):696–701.

    Article  CAS  Google Scholar 

  21. Martínez JM, Masoller N, Devlieger R, Passchyn E, Gómez O, Rodo J, et al. Laser ablation of posterior urethral valves by fetal cystoscopy. Fetal Diagn Ther. 2015;37(4):267–73.

    Article  Google Scholar 

  22. Ruano R, Sananes N, Sangi-Haghpeykar H, Hernandez-Ruano S, Moog R, Becmeur F, et al. Fetal intervention for severe lower urinary tract obstruction: a multicenter case-control study comparing fetal cystoscopy with vesicoamniotic shunting. Ultrasound Obstet Gynecol. 2015;45(4):452–8.

    Article  CAS  Google Scholar 

  23. Sananes N, Favre R, Koh CJ, et al. Urological fistulas after fetal cystoscopic laser ablation of posterior urethral valves—surgical technical aspects. Ultrasound Obstet Gynecol. 2015;6:66.

    Google Scholar 

  24. Miguelez J, Bunduki V, Yoshizaki CT, et al. Fetal obstructive uropathy: is urine sampling useful for prenatal counselling? Prenat Diagn. 2006;26:81–4.

    Article  Google Scholar 

  25. Lissauer D, Morris RK, Kilby MD. Fetal lower urinary tract obstruction. Semin Fetal Neonatal Med. 2007;12:464–70.

    Article  Google Scholar 

  26. Craparo FJ, Rustico M, Tassis B, et al. Fetal serum beta2microglobulin before and after bladder shunting: a 2-step approach to evaluate fetuses with lower urinary tract obstruction. J Urol. 2007;178:2576–9.

    Article  CAS  Google Scholar 

  27. Morris R, Malin G, Khan K, Kilby M. Antenatal ultrasound to predict postnatal renal function in congenital lower urinary tract obstruction: systematic review of test accuracy. BJOG. 2009;6:66.

    Google Scholar 

  28. Morris RK, et al. Percutaneous vesicoamniotic shunting versus conservative management for fetal lower urinary tract obstruction (PLUTO): a randomised trial. Lancet. 2013;382:9903. https://doi.org/10.1016/S0140-6736(13)60992-7.

    Article  Google Scholar 

  29. Morris RK, Ruano R, Kilby MD. Effectiveness of fetal cystoscopy as a diagnostic and therapeutic intervention for lower urinary tract obstruction: a systematic review. Ultrasound Obstet Gynecol. 2011;6:66.

    Google Scholar 

  30. Ruano R, Sananes N, Sangi-Haghpeykar H, Hernandez-Ruano S, Moog R, Becmeur F, et al. Fetal intervention for severe lower urinary tract obstruction: a multicenter case-control study comparing fetal cystoscopy with vesicoamniotic shunting. Ultrasound Obstet Gynecol. 2015;6:66.

    Google Scholar 

  31. Nassr AA, Shazly SA, Abdelmagied AM, Araujo Júnior E, Tonni G, Kilby MD, et al. Effectiveness of vesicoamniotic shunt in fetuses with congenital lower urinary tract obstruction: an updated systematic review and metaanalysis. Ultrasound Obstet Gynecol. 2017;6:66.

    Google Scholar 

  32. Shimada K, Hosokawa S, Tohda A, et al. Follow-up of children after fetal treatment for obstructive uropathy. Int J Urol. 1998;5:312–6.

    Article  CAS  Google Scholar 

  33. Vinit N, Gueneuc A, Bessières B, Dreux S, Heidet L, Salomon R, Lapillonne A, De Bernardis G, Salomon LJ, Stirnemann JJ, Blanc T, Ville Y. Fetal cystoscopy and vesicoamniotic shunting in lower urinary tract obstruction: long-term outcome and current technical limitations. Fetal Diagn Ther. 2020;47:74–83. https://doi.org/10.1159/000500569.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vivek Krishnan.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (AVI 13813 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lall, J., Abraham, M., Sreedhar, S. et al. Two Cases of Fetal Lower Urinary Tract Obstruction (LUTO) with Similar Presentations Before But Contrasting Outcomes After Fetoscopic Laser Fulguration of Posterior Urethral Valves. J. Fetal Med. 8, 203–210 (2021). https://doi.org/10.1007/s40556-021-00308-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40556-021-00308-4

Keywords

Navigation