Skip to main content
Log in

Sonographic Diagnosis of Omphalocele in the Second Trimester of Pregnancy

  • Brief Communication
  • Published:
Journal of Fetal Medicine

Abstract

Omphaloceles or exomphalos are congenital midline abdominal wall defects at the base of the umbilical cord insertion with herniation of gut and/or liver or occasionally other content, out of the fetal abdomen. Prenatal detection has significantly increased with a wide use of ultrasound and alpha-fetoprotein screening. Omphaloceles detected early in pregnancy and containing only bowel, have increased risk of associated anomalies and chromosomal disorders.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

References

  1. Georgiades CS. Etymology of selected medical terms used in radiology: the mythologic connection. AJR Am J Roentgenol. 2002;178(5):1101–7.

    Article  PubMed  Google Scholar 

  2. Emanuel PG, Garcia GI, Angtuaco TL. Prenatal detection of anterior abdominal wall defects with US. Radiographics. 1995;15(3):517–30.

    Article  CAS  PubMed  Google Scholar 

  3. Nicolaides KH, Snijders RJ, Cheng HH, Gosden C. Fetal gastro-intestinal and abdominal wall defects: associated malformations and chromosomal abnormalities. Fetal Diagn Ther. 1992;7:102–15.

    Article  CAS  PubMed  Google Scholar 

  4. Blazer S, Zimmer EZ, Gover A, Bronshtein M. Fetal omphalocele detected early in pregnancy: associated anomalies and outcomes. Radiology. 2004;232(1):191–5.

    Article  PubMed  Google Scholar 

  5. Kurkchubasche AG. The fetus with an abdominal wall defect. Med Health R I. 2001;84(5):159–61.

    CAS  PubMed  Google Scholar 

  6. van Zalen-Sprock RM, Vugt JM, van Geijn HP. First-trimester sonography of physiological midgut herniation and early diagnosis of omphalocele. Prenat Diagn. 1997;17:511–8.

    Article  PubMed  Google Scholar 

  7. Chen CP. Syndromes and disorders associated with omphalocele (III): single gene disorders, neural tube defects, diaphragmatic defects and others. Taiwan J Obstet Gynecol. 2007;46(2):111–20.

    Article  PubMed  Google Scholar 

  8. Chen C. Chromosomal abnormalities associated with omphalocele. Taiwan J Obstet Gynecol. 2007;46(1):1–8.

    Article  PubMed  Google Scholar 

  9. Curtis JA, Watson L. Sonographic diagnosis of omphalocele in the first trimester of fetal gestation. J Ultrasound Med. 1988;7:97–100.

    CAS  PubMed  Google Scholar 

  10. Getachew MM, Goldstein RB, Edge V, Goldberg JD, Filly RA. Correlation between omphalocele contents and karyotypic abnormalities: sonographic study in 37 cases. AJR Am J Roentgenol. 1992;158(1):133–6.

    Article  CAS  PubMed  Google Scholar 

  11. Ledbetter DJ. Gastroschisis and omphalocele. Surg Clin North Am. 2006;86(2):249–60.

    Article  PubMed  Google Scholar 

  12. Daltro P, Fricke BL, Kline-fath BM, Werner H, Rodrigues L, Fazecas T, et al. Prenatal MRI of congenital abdominal and chest wall defects. AJR Am J Roentgenol. 2005;184(3):1010–6.

    Article  PubMed  Google Scholar 

  13. Danzer E, Victoria T, Bebbington MW, Siegle J, Rintoul NE, Johnson MP, et al. Fetal MRI-calculated total lung volumes in the prediction of short-term outcome in giant omphalocele: preliminary findings. Fetal Diagn Ther. 2012;31(4):248–53.

    Article  PubMed  Google Scholar 

  14. Stoll C, Alembik Y, Dott B, Roth MP. Risk factors in congenital abdominal wall defect (omphalocele and gastroschisis): a study in a series of 265,858 consecutive births. Ann Genet. 2001;44:201–8.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rajendra Kumar Diwakar.

Ethics declarations

Conflict of interest

None.

Informed Consent

Consent from the patient has been obtained. Permission from institutional review committee has been obtained.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Diwakar, R.K., Chandrakar, K., Naik, M. et al. Sonographic Diagnosis of Omphalocele in the Second Trimester of Pregnancy. J. Fetal Med. 3, 45–48 (2016). https://doi.org/10.1007/s40556-016-0071-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40556-016-0071-5

Keywords

Navigation