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De-labeling Penicillin Allergy in Pediatric Population

  • Drug Allergy (M Audicana, Section Editor)
  • Published:
Current Treatment Options in Allergy Aims and scope Submit manuscript

Abstract

Purpose of review

At present, penicillin allergy in children is misdiagnosed, leading to undesirable health consequences; thus, a correct diagnosis is needed. De-labelling penicillin allergy strategies in pediatric population is emerging in order to achieve a correct antimicrobial management.

Recent findings

New protocols, specific for pediatric population, are rising from academic societies in order to improve penicillin allergy management in children, so unnecessary tests are avoided.

Summary

This document aims to provide guidance on how to de-label penicillin allergy in children through a correct diagnosis. The workup for penicillin allergy should be based on the characteristics and severity of the index reaction, which determine the indication and risk for performing a drug provocation test and the indication or nonperformance of previous allergy tests.

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Authors and Affiliations

  1. Allergy Department, Hospital Infantil Universitario Niño Jesús, Av. de Menéndez Pelayo, 65, 28009, Madrid, Spain

    Marta Bernaola MD & María Dolores Ibáñez-Sandín MD, PhD

  2. Allergy Department, Hospital Universitario Puerta de Hierro, Madrid, Spain

    Cristina Morales-Cabeza MD

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  1. Marta Bernaola MD
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  3. María Dolores Ibáñez-Sandín MD, PhD
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Correspondence to María Dolores Ibáñez-Sandín MD, PhD.

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Bernaola, M., Morales-Cabeza, C. & Ibáñez-Sandín, M.D. De-labeling Penicillin Allergy in Pediatric Population. Curr Treat Options Allergy 9, 234–249 (2022). https://doi.org/10.1007/s40521-022-00315-4

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