Current Treatment Options in Allergy

, Volume 5, Issue 1, pp 29–40 | Cite as

Asthma and Cleaning: What’s New?

  • Carole Ederle
  • Carole Donnay
  • Naji Khayath
  • Marie Mielcarek
  • Frederic de BlayEmail author
Occupational Allergy (S Quirce and J Sastre, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Occupational Allergy


Professional and domestic cleanings are associated with work-related asthma (WRA). Increased risk of asthma has been shown in many epidemiological and surveillance studies, and several case reports describe the relationship between exposure to one or more cleaning agents and WRA. Moreover, exposure to cleaning chemicals could be associated with severe uncontrolled asthma. Cleaning sprays, bleach, ammonia, disinfectants, mixing products, and specific job tasks have been identified as specific causes and/or triggers of asthma or airway respiratory diseases. Their measurements at the workplace could be interesting but hardly feasible. It is still under controversy whether cleaning products are airway irritants or sensitizers. The social consequence of unemployment in this population is one of the most important limitations to the management of occupational in cleaning professionals. The prognosis of the disease depends of removal from exposure, with avoidance of high-risk cleaning products, even at home.


Asthma Occupational Cleaners Irritant Chemicals Respiratory Review 


Compliance with ethical standards

Conflict of interest

Frederic de Blay reports grants from STALLERGENES-GREER, grants from CHIESI, personal fees from ALK, personal fees from MUNDIPHARMA, personal fees from NOVARTIS, during the conduct of the study; other from STALLERGENES-GREER, other from NOVARTIS, other from ALK, other from MUNDIPHARMA, other from MEDAPHARMA, other from BOEHRINGER, other from ASTRAZENECA, outside the submitted work.

Carole Ederle declares that she has no conflict of interest.

Carole Donnay declares that she has no conflict of interest.

Naji Khayath declares that he has no conflict of interest.

Marie Mielcarek declares that she has no conflict of interest.

Human and animal rights and informed consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Carole Ederle
    • 1
  • Carole Donnay
    • 2
  • Naji Khayath
    • 1
  • Marie Mielcarek
    • 3
  • Frederic de Blay
    • 1
    • 4
    Email author
  1. 1.Pole de pathologie thoracique Hopitaux Universitaires de Strasbourg, EA 3072Université de StrasbourgStrasbourgFrance
  2. 2.Service de pathologie professionnelleHopital CochinParisFrance
  3. 3.Service d’hygièneHopitaux Universitaires de StrasbourgStrasbourgFrance
  4. 4.StrasbourgFrance

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