Precision Medicine in Allergic Disorders
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The Era of Precision Medicine in Allergic Disorders
It is fully acknowledged in medical education that “There is no single disease as a general term that covers every patient, but there is individual characteristics and variations between patients and the treatment should focus on the individual patient not the disease.” This individual variability among patients has aroused the necessity for subcategorizations, tailoring, or customization of diseases. This concept has been brought up as “Ut quod ali cibus est aliis fuat acre venenum,” which means “What Is Food to One May Be Fierce Poison to Others”by Titus Lucretius Carus a Roman poet and philosopher for the description of food allergy (Wikipedia). Allergic patients have individual stories, different molecular mechanisms, different visible characteristics and disease outcomes under the influence of genetic background, and epigenetic control by micro- and macro-environment. Accordingly, the three keywords, endotype, phenotype, and...
KeywordsAllergy Component resolved diagnosis Precision medicine
References and Recommended Reading
- 2.Muraro A, Lemanske RF Jr, Hellings PW, Akdis CA, Bieber T, Casale TB, et al. Precision medicine in patients with allergic diseases: airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2016;137(5):1347–58. doi: 10.1016/j.jaci.2016.03.010.CrossRefPubMedGoogle Scholar