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Orthogeriatric co-management for the care of older subjects with hip fracture: recommendations from an Italian intersociety consensus

  • Consensus document
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Aging Clinical and Experimental Research Aims and scope Submit manuscript

Abstract

Background

Health outcomes of older subjects with hip fracture (HF) may be negatively influenced by multiple comorbidities and frailty. An integrated multidisciplinary approach (i.e. the orthogeriatric model) is, therefore, highly recommended, but its implementation in clinical practice suffers from the lack of shared management protocols and poor awareness of the problem. The present consensus document has been implemented to address these issues.

Aim

To develop evidence-based recommendations for the orthogeriatric co-management of older subjects with HF.

Methods

A 20-member Expert Task Force of geriatricians, orthopaedics, anaesthesiologists, physiatrists, physiotherapists and general practitioners was established to develop evidence-based recommendations for the pre-, peri-, intra- and postoperative care of older in-patients (≥ 65 years) with HF. A modified Delphi approach was used to achieve consensus, and the U.S. Preventive Services Task Force system was used to rate the strength of recommendations and the quality of evidence.

Results

A total of 120 recommendations were proposed, covering 32 clinical topics and concerning preoperative evaluation (11 topics), perioperative (8 topics) and intraoperative (3 topics) management, and postoperative care (10 topics).

Conclusion

These recommendations should ease and promote the multidisciplinary management of older subjects with HF by integrating the expertise of different specialists. By providing a convenient list of topics of interest, they might assist in identifying unmet needs and research priorities.

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References

  1. Programma Nazionale Esiti (PNE) (2020) Home. https://pne.agenas.it/index.php?lang=IT. Accessed 10 Apr 2021

  2. Haentjens P, Magaziner J, Colón-Emeric CS et al (2010) Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med 152:380–390. https://doi.org/10.7326/0003-4819-152-6-201003160-00008

    Article  PubMed  PubMed Central  Google Scholar 

  3. Maggi S, Siviero P, Wetle T et al (2010) A multicenter survey on profile of care for hip fracture: predictors of mortality and disability. Osteoporos Int 21:223–231. https://doi.org/10.1007/s00198-009-0936-8

    Article  CAS  PubMed  Google Scholar 

  4. Grigoryan KV, Javedan H, Rudolph JL (2014) Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma 28:e49-55. https://doi.org/10.1097/BOT.0b013e3182a5a045

    Article  PubMed  PubMed Central  Google Scholar 

  5. Mukherjee K, Brooks SE, Barraco RD et al (2020) Elderly adults with isolated hip fractures—orthogeriatric care versus standard care: a practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg 88:266–278. https://doi.org/10.1097/TA.0000000000002482

    Article  PubMed  Google Scholar 

  6. Ferrara MC, Andreano A, Tassistro E et al (2020) Three-year national report from the Gruppo Italiano di Ortogeriatria (GIOG) in the management of hip-fractured patients. Aging Clin Exp Res 32:1245–1253. https://doi.org/10.1007/s40520-020-01488-1

    Article  PubMed  Google Scholar 

  7. De Vincentis A, Behr AU, Bellelli G et al (2020) Management of hip fracture in the older people: rationale and design of the Italian consensus on the orthogeriatric co-management. Aging Clin Exp Res 32:1393–1399. https://doi.org/10.1007/s40520-020-01574-4

    Article  PubMed  Google Scholar 

  8. US Preventive Services Task Force, grade definitions. https://www.uspreventiveservicestaskforce.org/Page/Name/grade-definitions

  9. Sabharwal S, Wilson H (2015) Orthogeriatrics in the management of frail older patients with a fragility fracture. Osteoporos Int 26:2387–2399. https://doi.org/10.1007/s00198-015-3166-2

    Article  CAS  PubMed  Google Scholar 

  10. Kammerlander C, Roth T, Friedman SM et al (2010) Ortho-geriatric service—a literature review comparing different models. Osteoporos Int 21:S637-646. https://doi.org/10.1007/s00198-010-1396-x

    Article  CAS  PubMed  Google Scholar 

  11. Dyer SM, Perracini MR, Smith T et al (2021) Rehabilitation following hip fracture. In: Falaschi P, Marsh D (eds) Orthogeriatrics: the management of older patients with fragility fractures. Springer International Publishing, Cham, pp 183–222

    Chapter  Google Scholar 

  12. Ravi B, Jenkinson R, Austin PC et al (2014) Relation between surgeon volume and risk of complications after total hip arthroplasty: propensity score matched cohort study. BMJ 348:g3284. https://doi.org/10.1136/bmj.g3284

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Browne JA, Pietrobon R, Olson SA (2009) Hip fracture outcomes: does surgeon or hospital volume really matter? J Trauma 66:809–814. https://doi.org/10.1097/TA.0b013e31816166bb

    Article  PubMed  Google Scholar 

  14. Rubenstein LZ, Josephson KR, Wieland GD et al (1984) Effectiveness of a geriatric evaluation unit—a randomized clinical trial. N Engl J Med 311:1664–1670. https://doi.org/10.1056/NEJM198412273112604

    Article  CAS  PubMed  Google Scholar 

  15. Eamer G, Taheri A, Chen SS et al (2018) Comprehensive geriatric assessment for older people admitted to a surgical service. Cochrane Database Syst Rev 1:CD012485. https://doi.org/10.1002/14651858.CD012485.pub2

    Article  PubMed  Google Scholar 

  16. De Hert S, Staender S, Fritsch G et al (2018) Pre-operative evaluation of adults undergoing elective noncardiac surgery: updated guideline from the European Society of Anaesthesiology. Eur J Anaesthesiol 35:407–465. https://doi.org/10.1097/EJA.0000000000000817

    Article  PubMed  Google Scholar 

  17. Hardern RD, Sutcliffe J (1994) No more ‘routine’ chest radiographs in patients with proximal femoral fractures? Eur J Emerg Med 1:78–79

    Article  CAS  Google Scholar 

  18. Loggers SAI, Giannakopoulos GF, Vandewalle E et al (2017) Preoperative chest radiographs in hip fracture patients: is there any additional value? Eur J Orthop Surg Traumatol 27:953–959. https://doi.org/10.1007/s00590-017-1971-3

    Article  PubMed  PubMed Central  Google Scholar 

  19. Griffiths R, Alper J, Beckingsale A et al (2012) Management of proximal femoral fractures 2011. Anaesthesia 67:85–98. https://doi.org/10.1111/j.1365-2044.2011.06957.x

    Article  CAS  PubMed  Google Scholar 

  20. La gestione anestesiologica della frattura di femore nel paziente anziano. In: SIAARTI. https://www.siaarti.it/news/370736. Accessed 10 Apr 2021

  21. Duckworth AD, Phillips S-A, Stone O et al (2012) Deep infection after hip fracture surgery: predictors of early mortality. Injury 43:1182–1186. https://doi.org/10.1016/j.injury.2012.03.029

    Article  PubMed  Google Scholar 

  22. World Health Organization (2018) Global guidelines on the prevention of surgical site infection. http://www.who.int/infection-prevention/publications/ssi-guidelines/en/. Accessed 10 Apr 2021

  23. de Jonge SW, Boldingh QJJ, Solomkin JS et al (2020) Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysis. Lancet Infect Dis 20:1182–1192. https://doi.org/10.1016/S1473-3099(20)30084-0

    Article  PubMed  Google Scholar 

  24. Southwell-Keely JP, Russo RR, March L et al (2004) Antibiotic prophylaxis in hip fracture surgery: a metaanalysis. Clin Orthop Relat Res. https://doi.org/10.1097/00003086-200402000-00029

    Article  PubMed  Google Scholar 

  25. Călina D, Docea AO, Rosu L et al (2017) Antimicrobial resistance development following surgical site infections. Mol Med Rep 15:681–688. https://doi.org/10.3892/mmr.2016.6034

    Article  CAS  PubMed  Google Scholar 

  26. Thyagarajan D, Sunderamoorthy D, Haridas S et al (2009) MRSA colonisation in patients admitted with hip fracture: implications for prevention of surgical site infection. Acta Orthop Belg 75:252–257

    PubMed  Google Scholar 

  27. Nixon M, Jackson B, Varghese P et al (2006) Methicillin-resistant Staphylococcus aureus on orthopaedic wards: incidence, spread, mortality, cost and control. J Bone Joint Surg Br 88:812–817. https://doi.org/10.1302/0301-620X.88B6.17544

    Article  CAS  PubMed  Google Scholar 

  28. Bode LGM, Kluytmans JAJW, Wertheim HFL et al (2010) Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N Engl J Med 362:9–17. https://doi.org/10.1056/NEJMoa0808939

    Article  CAS  PubMed  Google Scholar 

  29. Sporer SM, Rogers T, Abella L (2016) Methicillin-resistant and methicillin-sensitive Staphylococcus aureus screening and decolonization to reduce surgical site infection in elective total joint arthroplasty. J Arthroplasty 31:144–147. https://doi.org/10.1016/j.arth.2016.05.019

    Article  PubMed  Google Scholar 

  30. Liu Z, Norman G, Iheozor-Ejiofor Z et al (2017) Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers. Cochrane Database Syst Rev 5:CD012462. https://doi.org/10.1002/14651858.CD012462.pub2

    Article  PubMed  Google Scholar 

  31. Bryson DJ, Gulihar A, Aujla RS et al (2015) The hip fracture best practice tariff: early surgery and the implications for MRSA screening and antibiotic prophylaxis. Eur J Orthop Surg Traumatol 25:123–127. https://doi.org/10.1007/s00590-014-1448-6

    Article  PubMed  Google Scholar 

  32. Iacchini S, Sabbatucci M, Gagliotti C et al (2019) Bloodstream infections due to carbapenemase-producing Enterobacteriaceae in Italy: results from nationwide surveillance, 2014 to 2017. Euro Surveill. https://doi.org/10.2807/1560-7917.ES.2019.24.5.1800159

    Article  PubMed  PubMed Central  Google Scholar 

  33. Masters J, Metcalfe D, Ha JS et al (2020) Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK. Bone Joint Res 9:554–562. https://doi.org/10.1302/2046-3758.99.BJR-2020-0023.R1

    Article  PubMed  PubMed Central  Google Scholar 

  34. Lawrence VA, Hilsenbeck SG, Noveck H et al (2002) Medical complications and outcomes after hip fracture repair. Arch Intern Med 162:2053–2057. https://doi.org/10.1001/archinte.162.18.2053

    Article  PubMed  Google Scholar 

  35. Rosencher N, Vielpeau C, Emmerich J et al (2005) Venous thromboembolism and mortality after hip fracture surgery: the ESCORTE study. J Thromb Haemost 3:2006–2014. https://doi.org/10.1111/j.1538-7836.2005.01545.x

    Article  CAS  PubMed  Google Scholar 

  36. Lo I-L, Siu C-W, Tse H-F et al (2010) Pre-operative pulmonary assessment for patients with hip fracture. Osteoporos Int 21:579–586. https://doi.org/10.1007/s00198-010-1427-7

    Article  PubMed Central  Google Scholar 

  37. Austin L, Pulido L, Ropiak R et al (2008) Hypoxemia after total joint arthroplasty: a problem on the rise. J Arthroplasty 23:1016–1021. https://doi.org/10.1016/j.arth.2008.05.006

    Article  PubMed  Google Scholar 

  38. Wang X, Dai L, Zhang Y et al (2020) Gender and low albumin and oxygen levels are risk factors for perioperative pneumonia in geriatric hip fracture patients. Clin Interv Aging 15:419–424. https://doi.org/10.2147/CIA.S241592

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Canet J, Gallart L, Gomar C et al (2010) Prediction of postoperative pulmonary complications in a population-based surgical cohort. Anesthesiology 113:1338–1350. https://doi.org/10.1097/ALN.0b013e3181fc6e0a

    Article  PubMed  Google Scholar 

  40. Qaseem A, Snow V, Fitterman N et al (2006) Risk assessment for and strategies to reduce perioperative pulmonary complications for patients undergoing noncardiothoracic surgery: a guideline from the American College of Physicians. Ann Intern Med 144:575–580. https://doi.org/10.7326/0003-4819-144-8-200604180-00008

    Article  PubMed  Google Scholar 

  41. Lee DJ, Elfar JC (2014) Timing of hip fracture surgery in the elderly. Geriatr Orthop Surg Rehabil 5:138–140. https://doi.org/10.1177/2151458514537273

    Article  PubMed  PubMed Central  Google Scholar 

  42. Pincus D, Ravi B, Wasserstein D et al (2017) Association between wait time and 30-day mortality in adults undergoing hip fracture surgery. JAMA 318:1994–2003. https://doi.org/10.1001/jama.2017.17606

    Article  PubMed  PubMed Central  Google Scholar 

  43. Moja L, Piatti A, Pecoraro V et al (2012) Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PLoS ONE 7:e46175. https://doi.org/10.1371/journal.pone.0046175

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Klestil T, Röder C, Stotter C et al (2018) Impact of timing of surgery in elderly hip fracture patients: a systematic review and meta-analysis. Sci Rep 8:13933. https://doi.org/10.1038/s41598-018-32098-7

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  45. Oakley B, Nightingale J, Moran CG et al (2017) Does achieving the best practice tariff improve outcomes in hip fracture patients? An observational cohort study. BMJ Open 7:e014190. https://doi.org/10.1136/bmjopen-2016-014190

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. NHS Scotland (2020) The Scottish hip fracture audit. https://www.shfa.scot.nhs.uk/. Accessed 10 Apr 2021

  47. The National Hip Fracture Database. https://www.nhfd.co.uk/. Accessed 10 Apr 2021

  48. Oliver CM, Hare S (2019) What do perioperative national clinical audits tell us? The evolving role of national audits in changing practice and improving outcomes. Br J Anaesth Educ 19:334–341. https://doi.org/10.1016/j.bjae.2019.05.004

    Article  CAS  Google Scholar 

  49. Forni S, Pieralli F, Sergi A et al (2016) Mortality after hip fracture in the elderly: the role of a multidisciplinary approach and time to surgery in a retrospective observational study on 23,973 patients. Arch Gerontol Geriatr 66:13–17. https://doi.org/10.1016/j.archger.2016.04.014

    Article  PubMed  Google Scholar 

  50. Joosse P, Loggers SAI, Van de Ree CLP et al (2019) The value of nonoperative versus operative treatment of frail institutionalized elderly patients with a proximal femoral fracture in the shade of life (FRAIL-HIP); protocol for a multicenter observational cohort study. BMC Geriatr 19:301. https://doi.org/10.1186/s12877-019-1324-7

    Article  PubMed  PubMed Central  Google Scholar 

  51. Schermann H, Gurel R, Gold A et al (2019) Safety of urgent hip fracture surgery protocol under influence of direct oral anticoagulation medications. Injury 50:398–402. https://doi.org/10.1016/j.injury.2018.10.033

    Article  PubMed  Google Scholar 

  52. NHS Scotland (2018) Consensus statement for management of anticoagulants and antiplatelet drugs in patients with hip fracture. https://www.shfa.scot.nhs.uk/_docs/2018/Consensus-Statement-for-Management-of-Anticoagulants-180913.pdf

  53. Yassa R, Khalfaoui MY, Hujazi I et al (2017) Management of anticoagulation in hip fractures: a pragmatic approach. EFORT Open Rev 2:394–402. https://doi.org/10.1302/2058-5241.2.160083

    Article  PubMed  PubMed Central  Google Scholar 

  54. Hornor MA, Duane TM, Ehlers AP et al (2018) American College of Surgeons’ guidelines for the perioperative management of antithrombotic medication. J Am Coll Surg 227:521-536.e1. https://doi.org/10.1016/j.jamcollsurg.2018.08.183

    Article  PubMed  Google Scholar 

  55. Steffel J, Verhamme P, Potpara TS et al (2018) The 2018 European heart rhythm association practical guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation. Eur Heart J 39:1330–1393. https://doi.org/10.1093/eurheartj/ehy136

    Article  CAS  Google Scholar 

  56. Heidbuchel H, Verhamme P, Alings M et al (2015) Updated European heart rhythm association practical guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation. Europace 17:1467–1507. https://doi.org/10.1093/europace/euv309

    Article  PubMed  Google Scholar 

  57. You D, Xu Y, Ponich B et al (2021) Effect of oral anticoagulant use on surgical delay and mortality in hip fracture. Bone Joint J 103-B:222–233. https://doi.org/10.1302/0301-620X.103B2.BJJ-2020-0583.R2

    Article  PubMed  Google Scholar 

  58. Meinig R, Jarvis S, Orlando A et al (2020) Is anticoagulation reversal necessary prior to surgical treatment of geriatric hip fractures? J Clin Orthop Trauma 11:S93–S99. https://doi.org/10.1016/j.jcot.2019.10.004

    Article  PubMed  Google Scholar 

  59. Leer-Salvesen S, Dybvik E, Ranhoff AH et al (2020) Do direct oral anticoagulants (DOACs) cause delayed surgery, longer length of hospital stay, and poorer outcome for hip fracture patients? Eur Geriatr Med 11:563–569. https://doi.org/10.1007/s41999-020-00319-w

    Article  PubMed  PubMed Central  Google Scholar 

  60. Bruckbauer M, Prexl O, Voelckel W et al (2019) Impact of direct oral anticoagulants in patients with hip fractures. J Orthop Trauma 33:e8–e13. https://doi.org/10.1097/BOT.0000000000001329

    Article  PubMed  Google Scholar 

  61. Gautier N, Pirson A, Lechat J-P et al (2020) Impact of direct oral anticoagulant therapy on operative delay, blood loss, transfusion and postoperative morbidity mortality in hip fracture patient, an observational study. Thromb Res 194:165–167. https://doi.org/10.1016/j.thromres.2020.06.021

    Article  CAS  PubMed  Google Scholar 

  62. Chassot P-G, Delabays A, Spahn DR (2007) Perioperative use of anti-platelet drugs. Best Pract Res Clin Anaesthesiol 21:241–256. https://doi.org/10.1016/j.bpa.2007.02.002

    Article  CAS  PubMed  Google Scholar 

  63. Jang C-Y, Kwak D-K, Kim D-H et al (2019) Perioperative antiplatelet in elderly patients aged over 70 years treated with proximal femur fracture: continue or discontinue? BMC Musculoskelet Disord 20:124. https://doi.org/10.1186/s12891-019-2504-5

    Article  PubMed  PubMed Central  Google Scholar 

  64. Mattesi L, Noailles T, Rosencher N et al (2016) Discontinuation of Plavix® (clopidogrel) for hip fracture surgery. A systematic review of the literature. Orthop Traumatol-Surg 102:1097–1101. https://doi.org/10.1016/j.otsr.2016.08.022

    Article  CAS  Google Scholar 

  65. Soo CGKM, Torre PKD, Yolland TJ et al (2016) Clopidogrel and hip fractures, is it safe? A systematic review and meta-analysis. BMC Musculoskelet Disord 17:136. https://doi.org/10.1186/s12891-016-0988-9

    Article  PubMed  PubMed Central  Google Scholar 

  66. Yang Z, Ni J, Long Z et al (2020) Is hip fracture surgery safe for patients on antiplatelet drugs and is it necessary to delay surgery? A systematic review and meta-analysis. J Orthop Surg Res 15:105. https://doi.org/10.1186/s13018-020-01624-7

    Article  PubMed  PubMed Central  Google Scholar 

  67. Huette P, Abou-Arab O, Djebara A-E et al (2020) Risk factors and mortality of patients undergoing hip fracture surgery: a one-year follow-up study. Sci Rep 10:9607. https://doi.org/10.1038/s41598-020-66614-5

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  68. Purushothaman B, Webb M, Weusten A et al (2016) Decision making on timing of surgery for hip fracture patients on clopidogrel. Ann R Coll Surg Engl 98:91–95. https://doi.org/10.1308/rcsann.2015.0041

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  69. Tarrant SM, Kim RG, McGregor KL et al (2020) Dual antiplatelet therapy and surgical timing in geriatric hip fracture. J Orthop Trauma 34:559–565. https://doi.org/10.1097/BOT.0000000000001779

    Article  PubMed  Google Scholar 

  70. Vásquez RSV, Romero RP (2015) Aspirin and spinal haematoma after neuraxial anaesthesia: myth or reality? Br J Anaesth 115:688–698. https://doi.org/10.1093/bja/aev348

    Article  CAS  Google Scholar 

  71. Horlocker TT, Wedel DJ, Benzon H et al (2003) Regional anesthesia in the anticoagulated patient: defining the risks (the second ASRA consensus conference on neuraxial anesthesia and anticoagulation). Reg Anesth Pain Med 28:172–197. https://doi.org/10.1053/rapm.2003.50046

    Article  PubMed  Google Scholar 

  72. Saletti-Cuesta L, Tutton E, Langstaff D et al (2017) Understanding patient and relative/carer experience of hip fracture in acute care: a qualitative study protocol. Int J Orthop Trauma Nurs 25:36–41. https://doi.org/10.1016/j.ijotn.2016.09.002

    Article  PubMed  Google Scholar 

  73. National Institute for Health and Care Excellence (2017) Hip fracture: management clinical guideline 124. https://www.nice.org.uk/guidance/cg124. Accessed 10 Apr 2021

  74. Asif M, Cadel L, Kuluski K et al (2020) Patient and caregiver experiences on care transitions for adults with a hip fracture: a scoping review. Disabil Rehabil 42:3549–3558. https://doi.org/10.1080/09638288.2019.1595181

    Article  PubMed  Google Scholar 

  75. Backman C, Cho-Young D (2019) Engaging patients and informal caregivers to improve safety and facilitate person- and family-centered care during transitions from hospital to home—a qualitative descriptive study. Patient Prefer Adherence 13:617–626. https://doi.org/10.2147/PPA.S201054

    Article  PubMed  PubMed Central  Google Scholar 

  76. Glenny C, Stolee P, Sheiban L et al (2013) Communicating during care transitions for older hip fracture patients: family caregiver and health care provider’s perspectives. Int J Integr Care 13:4. https://doi.org/10.5334/ijic.1076

    Article  Google Scholar 

  77. Shyu Y-IL, Chen M-C, Wu C-C et al (2010) Family caregivers’ needs predict functional recovery of older care recipients after hip fracture. J Adv Nurs 66:2450–2459. https://doi.org/10.1111/j.1365-2648.2010.05418.x

    Article  PubMed  Google Scholar 

  78. Sims-Gould J, Byrne K, Hicks E et al (2012) Examining ‘success’ in post-hip fracture care transitions: a strengths-based approach. J Interprof Care 26:205–211. https://doi.org/10.3109/13561820.2011.645090

    Article  PubMed  Google Scholar 

  79. Scurrah A, Shiner CT, Stevens JA et al (2018) Regional nerve blockade for early analgesic management of elderly patients with hip fracture—a narrative review. Anaesthesia 73:769–783. https://doi.org/10.1111/anae.14178

    Article  CAS  PubMed  Google Scholar 

  80. Cowan R, Lim JH, Ong T et al (2017) The challenges of anaesthesia and pain relief in hip fracture care. Drugs Aging 34:1–11. https://doi.org/10.1007/s40266-016-0427-5

    Article  CAS  PubMed  Google Scholar 

  81. Fabi DW (2016) Multimodal analgesia in the hip fracture patient. J Orthop Trauma 30:S6–S11. https://doi.org/10.1097/BOT.0000000000000561

    Article  PubMed  Google Scholar 

  82. Soffin EM, Gibbons MM, Ko CY et al (2019) Evidence review conducted for the agency for healthcare research and quality safety program for improving surgical care and recovery: focus on anesthesiology for total knee arthroplasty. Anesth Analg 128:441–453. https://doi.org/10.1213/ANE.0000000000003564

    Article  PubMed  Google Scholar 

  83. Chin RP-H, Ho C-H, Cheung LP-C (2013) Scheduled analgesic regimen improves rehabilitation after hip fracture surgery. Clin Orthop Relat Res 471:2349–2360. https://doi.org/10.1007/s11999-013-2927-5

    Article  PubMed  PubMed Central  Google Scholar 

  84. Bollinger AJ, Butler PD, Nies MS et al (2015) Is scheduled intravenous acetaminophen effective in the pain management protocol of geriatric hip fractures? Geriatr Orthop Surg Rehabil 6:202–208. https://doi.org/10.1177/2151458515588560

    Article  PubMed  PubMed Central  Google Scholar 

  85. Abdulla A, Bone M, Adams N et al (2013) Evidence-based clinical practice guidelines on management of pain in older people. Age Ageing 42:151–153. https://doi.org/10.1093/ageing/afs199

    Article  PubMed  Google Scholar 

  86. Morrison RS, Magaziner J, Gilbert M et al (2003) Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci 58:76–81. https://doi.org/10.1093/gerona/58.1.m76

    Article  PubMed  Google Scholar 

  87. Hsu C-S, Kao J-H, Chao Y-C et al (2013) Interferon-based therapy reduces risk of stroke in chronic hepatitis C patients: a population-based cohort study in Taiwan. Aliment Pharmacol Ther 38:415–423. https://doi.org/10.1111/apt.12391

    Article  CAS  PubMed  Google Scholar 

  88. Todd KH (2017) A review of current and emerging approaches to pain management in the emergency department. Pain Ther 6:193–202. https://doi.org/10.1007/s40122-017-0090-5

    Article  PubMed  PubMed Central  Google Scholar 

  89. American Academy of Orthopaedic Surgeons (AAOS) (2014) Management of hip fractures in the elderly evidence-based clinical practice guideline. In: AAOS. https://www.aaos.org/globalassets/quality-and-practice-resources/hip-fractures-in-the-elderly/hip-fractures-elderly-clinical-practice-guideline-4-24-19--2.pdf.

  90. Guay J, Parker MJ, Griffiths R et al (2018) Peripheral nerve blocks for hip fractures: a Cochrane review. Anesth Analg 126:1695–1704. https://doi.org/10.1213/ANE.0000000000002489

    Article  PubMed  Google Scholar 

  91. Odor PM, Chis Ster I, Wilkinson I et al (2017) Effect of admission fascia iliaca compartment blocks on post-operative abbreviated mental test scores in elderly fractured neck of femur patients: a retrospective cohort study. BMC Anesthesiol 17:2. https://doi.org/10.1186/s12871-016-0297-8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  92. Agrawal S, Turk R, Burton BN et al (2020) The association of preoperative delirium with postoperative outcomes following hip surgery in the elderly. J Clin Anesth 60:28–33. https://doi.org/10.1016/j.jclinane.2019.08.015

    Article  PubMed  Google Scholar 

  93. Gustafson Y, Berggren D, Brännström B et al (1988) Acute confusional states in elderly patients treated for femoral neck fracture. J Am Geriatr Soc 36:525–530. https://doi.org/10.1111/j.1532-5415.1988.tb04023.x

    Article  CAS  PubMed  Google Scholar 

  94. Bellelli G, Carnevali L, Corsi M et al (2018) The impact of psychomotor subtypes and duration of delirium on 6-month mortality in hip-fractured elderly patients. Int J Geriatr Psychiatry 33:1229–1235. https://doi.org/10.1002/gps.4914

    Article  Google Scholar 

  95. Bellelli G, Mazzola P, Morandi A et al (2014) Duration of postoperative delirium is an independent predictor of 6-month mortality in older adults after hip fracture. J Am Geriatr Soc 62:1335–1340. https://doi.org/10.1111/jgs.12885

    Article  PubMed  Google Scholar 

  96. Lee HB, Oldham MA, Sieber FE et al (2017) Impact of delirium after hip fracture surgery on one-year mortality in patients with or without dementia: a case of effect modification. Am J Geriatr Psychiatry 25:308–315. https://doi.org/10.1016/j.jagp.2016.10.008

    Article  PubMed  Google Scholar 

  97. Hamilton GM, Wheeler K, Di Michele J et al (2017) A systematic review and meta-analysis examining the impact of incident postoperative delirium on mortality. Anesthesiology 127:78–88. https://doi.org/10.1097/ALN.0000000000001660

    Article  PubMed  Google Scholar 

  98. Marcantonio ER, Flacker JM, Michaels M et al (2000) Delirium is independently associated with poor functional recovery after hip fracture. J Am Geriatr Soc 48:618–624. https://doi.org/10.1111/j.1532-5415.2000.tb04718.x

    Article  CAS  PubMed  Google Scholar 

  99. Morandi A, Mazzone A, Bernardini B et al (2019) Association between delirium, adverse clinical events and functional outcomes in older patients admitted to rehabilitation settings after a hip fracture: a multicenter retrospective cohort study. Geriatr Gerontol Int 19:404–408. https://doi.org/10.1111/ggi.13628

    Article  PubMed  Google Scholar 

  100. Morandi A, Davis D, Fick DM et al (2014) Delirium superimposed on dementia strongly predicts worse outcomes in older rehabilitation inpatients. J Am Med Dir Assoc 15:349–354. https://doi.org/10.1016/j.jamda.2013.12.084

    Article  PubMed  PubMed Central  Google Scholar 

  101. Quispel-Aggenbach DWP, Holtman GA, Zwartjes HAHT et al (2018) Attention, arousal and other rapid bedside screening instruments for delirium in older patients: a systematic review of test accuracy studies. Age Ageing 47:644–653. https://doi.org/10.1093/ageing/afy058

    Article  CAS  PubMed  Google Scholar 

  102. Shenkin SD, Fox C, Godfrey M et al (2019) Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method. BMC Med 17:138. https://doi.org/10.1186/s12916-019-1367-9

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  103. Bellelli G, Morandi A, Davis DHJ et al (2014) Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalised older people. Age Ageing 43:496–502. https://doi.org/10.1093/ageing/afu021

    Article  PubMed  PubMed Central  Google Scholar 

  104. Oberai T, Laver K, Crotty M et al (2018) Effectiveness of multicomponent interventions on incidence of delirium in hospitalized older patients with hip fracture: a systematic review. Int Psychogeriatr 30:481–492. https://doi.org/10.1017/S1041610217002782

    Article  PubMed  Google Scholar 

  105. Shields L, Henderson V, Caslake R (2017) Comprehensive geriatric assessment for prevention of delirium after hip fracture: a systematic review of randomized controlled trials. J Am Geriatr Soc 65:1559–1565. https://doi.org/10.1111/jgs.14846

    Article  PubMed  Google Scholar 

  106. Tobu S, Noguchi M, Hashikawa T et al (2014) Risk factors of postoperative urinary retention after hip surgery for femoral neck fracture in elderly women. Geriatr Gerontol Int 14:636–639. https://doi.org/10.1111/ggi.12150

    Article  PubMed  Google Scholar 

  107. Kim JY, Yoo JH, Kim E et al (2017) Risk factors and clinical outcomes of delirium in osteoporotic hip fractures. J Orthop Surg (Hong Kong) 25:2309499017739485. https://doi.org/10.1177/2309499017739485

    Article  Google Scholar 

  108. Sørbye LW, Grue EV (2013) Hip fracture and urinary incontinence—use of indwelling catheter postsurgery. Scand J Caring Sci 27:632–642. https://doi.org/10.1111/j.1471-6712.2012.01075.x

    Article  PubMed  Google Scholar 

  109. Hu F-W, Shih H-I, Hsu H-C et al (2018) Dynamic changes in the appropriateness of urinary catheter use among hospitalized older patients in the emergency department. PLoS ONE 13:e0193905. https://doi.org/10.1371/journal.pone.0193905

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  110. Kwak D-K, Oh C-Y, Lim J-S et al (2019) Would early removal of indwelling catheter effectively prevent urinary retention after hip fracture surgery in elderly patients? J Orthop Surg Res 14:315. https://doi.org/10.1186/s13018-019-1360-1

    Article  PubMed  PubMed Central  Google Scholar 

  111. Joelsson-Alm E, Ulfvarson J, Nyman CR et al (2012) Preoperative ultrasound monitoring can reduce postoperative bladder distension: a randomized study. Scand J Urol Nephrol 46:84–90. https://doi.org/10.3109/00365599.2011.637959

    Article  PubMed  Google Scholar 

  112. Kort NP, Bemelmans Y, Vos R et al (2018) Low incidence of postoperative urinary retention with the use of a nurse-led bladder scan protocol after hip and knee arthroplasty: a retrospective cohort study. Eur J Orthop Surg Traumatol 28:283–289. https://doi.org/10.1007/s00590-017-2042-5

    Article  CAS  PubMed  Google Scholar 

  113. Thakker A, Briggs N, Maeda A et al (2018) Reducing the rate of post-surgical urinary tract infections in orthopedic patients. BMJ Open Qual 7:e000177. https://doi.org/10.1136/bmjoq-2017-000177

    Article  PubMed  PubMed Central  Google Scholar 

  114. Nyman MH, Johansson J-E, Gustafsson M (2010) A randomised controlled trial on the effect of clamping the indwelling urinary catheter in patients with hip fracture. J Clin Nurs 19:405–413. https://doi.org/10.1111/j.1365-2702.2009.03050.x

    Article  PubMed  Google Scholar 

  115. Johansson R-M, Christensson L (2010) Urinary retention in older patients in connection with hip fracture surgery. J Clin Nurs 19:2110–2116. https://doi.org/10.1111/j.1365-2702.2010.03261.x

    Article  PubMed  Google Scholar 

  116. Marsland D, Mears SC, Kates SL (2010) Venous thromboembolic prophylaxis for hip fractures. Osteoporos Int 21:S593-604. https://doi.org/10.1007/s00198-010-1403-2

    Article  CAS  PubMed  Google Scholar 

  117. Farfan M, Bautista M, Bonilla G et al (2016) Worldwide adherence to ACCP guidelines for thromboprophylaxis after major orthopedic surgery: a systematic review of the literature and meta-analysis. Thromb Res 141:163–170. https://doi.org/10.1016/j.thromres.2016.03.029

    Article  CAS  PubMed  Google Scholar 

  118. Falck-Ytter Y, Francis CW, Johanson NA et al (2012) Prevention of VTE in orthopedic surgery patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 141:e278S-e325S. https://doi.org/10.1378/chest.11-2404

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  119. Agnelli G, Mancini GB, Biagini D (2000) The rationale for long-term prophylaxis of venous thromboembolism. Orthopedics 23:s643-646

    CAS  PubMed  Google Scholar 

  120. Goisser S, Schrader E, Singler K et al (2015) Malnutrition according to mini nutritional assessment is associated with severe functional impairment in geriatric patients before and up to 6 months after hip fracture. J Am Med Dir Assoc 16:661–667. https://doi.org/10.1016/j.jamda.2015.03.002

    Article  PubMed  Google Scholar 

  121. Drevet S, Bioteau C, Mazière S et al (2014) Prevalence of protein-energy malnutrition in hospital patients over 75 years of age admitted for hip fracture. Orthop Traumatol Surg Res 100:669–674. https://doi.org/10.1016/j.otsr.2014.05.003

    Article  CAS  PubMed  Google Scholar 

  122. Mazzola P, Ward L, Zazzetta S et al (2017) Association between preoperative malnutrition and postoperative delirium after hip fracture surgery in older adults. J Am Geriatr Soc 65:1222–1228. https://doi.org/10.1111/jgs.14764

    Article  PubMed  PubMed Central  Google Scholar 

  123. Li H-J, Cheng H-S, Liang J et al (2013) Functional recovery of older people with hip fracture: does malnutrition make a difference? J Adv Nurs 69:1691–1703. https://doi.org/10.1111/jan.12027

    Article  PubMed  Google Scholar 

  124. Gumieiro DN, Rafacho BPM, Gonçalves AF et al (2013) Mini nutritional assessment predicts gait status and mortality 6 months after hip fracture. Br J Nutr 109:1657–1661. https://doi.org/10.1017/S0007114512003686

    Article  CAS  PubMed  Google Scholar 

  125. Duncan DG, Beck SJ, Hood K et al (2006) Using dietetic assistants to improve the outcome of hip fracture: a randomised controlled trial of nutritional support in an acute trauma ward. Age Ageing 35:148–153. https://doi.org/10.1093/ageing/afj011

    Article  PubMed  Google Scholar 

  126. Liu M, Yang J, Yu X et al (2015) The role of perioperative oral nutritional supplementation in elderly patients after hip surgery. Clin Interv Aging 10:849–858. https://doi.org/10.2147/CIA.S74951

    Article  PubMed  PubMed Central  Google Scholar 

  127. Avenell A, Smith TO, Curtain JP et al (2016) Nutritional supplementation for hip fracture aftercare in older people. Cochrane Database Syst Rev 11:CD001880. https://doi.org/10.1002/14651858.CD001880.pub6

    Article  PubMed  Google Scholar 

  128. Noba L, Wakefield A (2019) Are carbohydrate drinks more effective than preoperative fasting: a systematic review of randomised controlled trials. J Clin Nurs 28:3096–3116. https://doi.org/10.1111/jocn.14919

    Article  PubMed  Google Scholar 

  129. Arkley J, Dixon J, Wilson F et al (2019) Assessment of nutrition and supplementation in patients with hip fractures. Geriatr Orthop Surg Rehabil 10:2151459319879804. https://doi.org/10.1177/2151459319879804

    Article  PubMed  PubMed Central  Google Scholar 

  130. Harrison SJ, Messner J, Leeder DJ et al (2017) Are albumin levels a good predictor of mortality in elderly patients with neck of femur fractures? J Nutr Health Aging 21:699–703. https://doi.org/10.1007/s12603-016-0799-6

    Article  CAS  PubMed  Google Scholar 

  131. Hao L, Carson JL, Schlussel Y et al (2020) Vitamin D deficiency is associated with reduced mobility after hip fracture surgery: a prospective study. Am J Clin Nutr 112:613–618. https://doi.org/10.1093/ajcn/nqaa029

    Article  PubMed  PubMed Central  Google Scholar 

  132. Abdel MP, Watts CD, Houdek MT et al (2016) Epidemiology of periprosthetic fracture of the femur in 32 644 primary total hip arthroplasties: a 40-year experience. Bone Joint J 98-B:461–467. https://doi.org/10.1302/0301-620X.98B4.37201

    Article  CAS  PubMed  Google Scholar 

  133. Healey JS, Merchant R, Simpson C et al (2012) Society position statement. Can J Anesth/J Can Anesth 59:394–407. https://doi.org/10.1007/s12630-012-9678-8

    Article  Google Scholar 

  134. Meersch M, Schmidt C, Zarbock A (2016) Patient with chronic renal failure undergoing surgery. Curr Opin Anaesthesiol 29:413–420. https://doi.org/10.1097/ACO.0000000000000329

    Article  CAS  PubMed  Google Scholar 

  135. Kanda H, Hirasaki Y, Iida T et al (2017) Perioperative management of patients with end-stage renal disease. J Cardiothorac Vasc Anesth 31:2251–2267. https://doi.org/10.1053/j.jvca.2017.04.019

    Article  PubMed  Google Scholar 

  136. Ryan G, Nowak L, Melo L et al (2020) Anemia at presentation predicts acute mortality and need for readmission following geriatric hip fracture. JBJS Open Access 5:e20.00048. https://doi.org/10.2106/JBJS.OA.20.00048

    Article  PubMed  PubMed Central  Google Scholar 

  137. Puckeridge G, Terblanche M, Wallis M et al (2019) Blood management in hip fractures; are we leaving it too late? A retrospective observational study. BMC Geriatr 19:79. https://doi.org/10.1186/s12877-019-1099-x

    Article  PubMed  PubMed Central  Google Scholar 

  138. Porter CJ, Moppett IK, Juurlink I et al (2017) Acute and chronic kidney disease in elderly patients with hip fracture: prevalence, risk factors and outcome with development and validation of a risk prediction model for acute kidney injury. BMC Nephrol 18:20. https://doi.org/10.1186/s12882-017-0437-5

    Article  PubMed  PubMed Central  Google Scholar 

  139. Norring-Agerskov D, Madsen CM, Abrahamsen B et al (2017) Hyperkalemia is associated with increased 30-day mortality in hip fracture patients. Calcif Tissue Int 101:9–16. https://doi.org/10.1007/s00223-017-0252-9

    Article  CAS  PubMed  Google Scholar 

  140. Schiara LAM, Moirano G, Grosso E et al (2020) Hyponatremia, hypokalemia, and fragility fractures in old patients: more than an association? Calcif Tissue Int 106:599–607. https://doi.org/10.1007/s00223-020-00675-6

    Article  CAS  PubMed  Google Scholar 

  141. Lin YC, Hsu YC, Wu WT et al (2021) The incidence of severe urinary tract infection increases after hip fracture in the elderly: a nationwide cohort study. Sci Rep 11:3374. https://doi.org/10.1038/s41598-021-83091-6

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  142. Salarbaks AM, Lindeboom R, Nijmeijer W (2020) Pneumonia in hospitalized elderly hip fracture patients: the effects on length of hospital-stay, in-hospital and thirty-day mortality and a search for potential predictors. Injury 51:1846–1850. https://doi.org/10.1016/j.injury.2020.05.017

    Article  CAS  PubMed  Google Scholar 

  143. Lauretani F, Frondini C, Davoli ML et al (2012) Vitamin D supplementation is required to normalize serum level of 25OH-vitamin D in older adults: an observational study of 974 hip fracture inpatients. J Endocrinol Invest 35:921–924. https://doi.org/10.3275/8457

    Article  CAS  PubMed  Google Scholar 

  144. Yao P, Bennett D, Mafham M et al (2019) Vitamin D and calcium for the prevention of fracture: a systematic review and meta-analysis. JAMA Netw Open 2:e1917789. https://doi.org/10.1001/jamanetworkopen.2019.17789

    Article  PubMed  PubMed Central  Google Scholar 

  145. Fakler JKM, Grafe A, Dinger J et al (2016) Perioperative risk factors in patients with a femoral neck fracture—influence of 25-hydroxyvitamin D and C-reactive protein on postoperative medical complications and 1-year mortality. BMC Musculoskelet Disord 17:51. https://doi.org/10.1186/s12891-016-0906-1

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  146. Gleich J, Pfeufer D, Zeckey C et al (2019) Orthogeriatric treatment reduces potential inappropriate medication in older trauma patients: a retrospective, dual-center study comparing conventional trauma care and co-managed treatment. Eur J Med Res 24:4. https://doi.org/10.1186/s40001-019-0362-0

    Article  PubMed  PubMed Central  Google Scholar 

  147. Brunetti E, Aurucci ML, Boietti E et al (2019) Clinical implications of potentially inappropriate prescribing according to STOPP/START version 2 criteria in older polymorbid patients discharged from geriatric and internal medicine wards: a prospective observational multicenter study. J Am Med Dir Assoc 20:1476.e1-1476.e10. https://doi.org/10.1016/j.jamda.2019.03.023

    Article  Google Scholar 

  148. De Vincentis A, Gallo P, Finamore P et al (2020) Potentially inappropriate medications, drug-drug interactions, and anticholinergic burden in elderly hospitalized patients: does an association exist with post-discharge health outcomes? Drugs Aging 37:585–593. https://doi.org/10.1007/s40266-020-00767-w

    Article  CAS  PubMed  Google Scholar 

  149. De Vincentis A, Pedone C, Nobili A et al (2021) Authors’ reply to Brunetti et al. “Potentially inappropriate medications, drug-drug interactions, and anticholinergic burden in elderly hospitalized patients: does an association exist with post-discharge health outcomes?” Drugs Aging 38:93–94. https://doi.org/10.1007/s40266-020-00819-1

    Article  PubMed  Google Scholar 

  150. American Geriatrics Society Beers Criteria® Update Expert Panel (2019) American Geriatrics Society 2019 Updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc 67:674–694. https://doi.org/10.1111/jgs.15767

    Article  Google Scholar 

  151. O’Mahony D, O’Sullivan D, Byrne S et al (2015) STOPP/START criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing 44:213–218. https://doi.org/10.1093/ageing/afu145

    Article  PubMed  Google Scholar 

  152. Pazan F, Weiss C, Wehling M et al (2018) The EURO-FORTA (Fit fOR The Aged) list: international consensus validation of a clinical tool for improved drug treatment in older people. Drugs Aging 35:61–71. https://doi.org/10.1007/s40266-017-0514-2

    Article  PubMed  Google Scholar 

  153. Gjerde AM, Aa E, Sund JK et al (2016) Medication reconciliation of patients with hip fracture by clinical pharmacists. Eur J Hosp Pharm 23:166–170. https://doi.org/10.1136/ejhpharm-2015-000741

    Article  PubMed  Google Scholar 

  154. Wolf O, Åberg H, Tornberg U et al (2016) Do orthogeriatric inpatients have a correct medication list? A pharmacist-led assessment of 254 patients in a Swedish university hospital. Geriatr Orthop Surg Rehabil 7:18–22. https://doi.org/10.1177/2151458515625295

    Article  PubMed  PubMed Central  Google Scholar 

  155. Komagamine J, Hagane K (2017) Intervention to improve the appropriate use of polypharmacy for older patients with hip fractures: an observational study. BMC Geriatr 17:288. https://doi.org/10.1186/s12877-017-0681-3

    Article  PubMed  PubMed Central  Google Scholar 

  156. Guay J, Parker MJ, Gajendragadkar PR et al (2016) Anaesthesia for hip fracture surgery in adults. Cochrane Database Syst Rev 2:CD000521. https://doi.org/10.1002/14651858.CD000521.pub3

    Article  PubMed  Google Scholar 

  157. White SM, Moppett IK, Griffiths R (2014) Outcome by mode of anaesthesia for hip fracture surgery. An observational audit of 65 535 patients in a national dataset. Anaesthesia 69:224–230. https://doi.org/10.1111/anae.12542

    Article  CAS  PubMed  Google Scholar 

  158. Morgan L, McKeever TM, Nightingale J et al (2020) Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score-matching. Anaesthesia 75:1173–1179. https://doi.org/10.1111/anae.15042

    Article  CAS  PubMed  Google Scholar 

  159. White SM, Moppett IK, Griffiths R et al (2016) Secondary analysis of outcomes after 11,085 hip fracture operations from the prospective UK anaesthesia sprint audit of practice (ASAP-2). Anaesthesia 71:506–514. https://doi.org/10.1111/anae.13415

    Article  CAS  PubMed  Google Scholar 

  160. White SM, Altermatt F, Barry J et al (2018) International Fragility Fracture Network Delphi consensus statement on the principles of anaesthesia for patients with hip fracture. Anaesthesia 73:863–874. https://doi.org/10.1111/anae.14225

    Article  CAS  PubMed  Google Scholar 

  161. Shelton C, White S (2020) Anaesthesia for hip fracture repair. BJA Educ 20:142–149. https://doi.org/10.1016/j.bjae.2020.02.003

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  162. Bonnaire F, Zenker H, Lill C et al (2005) Treatment strategies for proximal femur fractures in osteoporotic patients. Osteoporos Int 16:S93–S102. https://doi.org/10.1007/s00198-004-1746-7

    Article  PubMed  Google Scholar 

  163. Okike K, Udogwu UN, Isaac M et al (2019) Not all Garden-I and II femoral neck fractures in the elderly should be fixed: effect of posterior tilt on rates of subsequent arthroplasty. J Bone Joint Surg Am 101:1852–1859. https://doi.org/10.2106/JBJS.18.01256

    Article  PubMed  Google Scholar 

  164. Arirachakaran A, Amphansap T, Thanindratarn P et al (2017) Comparative outcome of PFNA, Gamma nails, PCCP, Medoff plate, LISS and dynamic hip screws for fixation in elderly trochanteric fractures: a systematic review and network meta-analysis of randomized controlled trials. Eur J Orthop Surg Traumatol 27:937–952. https://doi.org/10.1007/s00590-017-1964-2

    Article  PubMed  Google Scholar 

  165. Hao Z, Wang X, Zhang X (2018) Comparing surgical interventions for intertrochanteric hip fracture by blood loss and operation time: a network meta-analysis. J Orthop Surg Res 13:157. https://doi.org/10.1186/s13018-018-0852-8

    Article  PubMed  PubMed Central  Google Scholar 

  166. Keating JF, Grant A, Masson M et al (2005) Displaced intracapsular hip fractures in fit, older people: a randomised comparison of reduction and fixation, bipolar hemiarthroplasty and total hip arthroplasty. Health Technol Assess. https://doi.org/10.3310/hta9410

    Article  PubMed  Google Scholar 

  167. Blomfeldt R, Törnkvist H, Ponzer S et al (2005) Internal fixation versus hemiarthroplasty for displaced fractures of the femoral neck in elderly patients with severe cognitive impairment. J Bone Joint Surg Br 87-B:523–529. https://doi.org/10.1302/0301-620X.87B4.15764

    Article  Google Scholar 

  168. Macaulay W, Nellans KW, Iorio R et al (2008) Total hip arthroplasty is less painful at 12 months compared with hemiarthroplasty in treatment of displaced femoral neck fracture. HSS J 4:48–54. https://doi.org/10.1007/s11420-007-9061-4

    Article  PubMed  Google Scholar 

  169. Bhandari M, Swiontkowski M (2017) Management of acute hip fracture. N Engl J Med 377:2053–2062. https://doi.org/10.1056/NEJMcp1611090

    Article  PubMed  Google Scholar 

  170. Migliorini F, Trivellas A, Driessen A et al (2020) Hemiarthroplasty versus total arthroplasty for displaced femoral neck fractures in the elderly: meta-analysis of randomized clinical trials. Arch Orthop Trauma Surg 140:1695–1704. https://doi.org/10.1007/s00402-020-03409-3

    Article  PubMed  Google Scholar 

  171. Deangelis JP, Ademi A, Staff I et al (2012) Cemented versus uncemented hemiarthroplasty for displaced femoral neck fractures: a prospective randomized trial with early follow-up. J Orthop Trauma 26:135–140. https://doi.org/10.1097/BOT.0b013e318238b7a5

    Article  PubMed  Google Scholar 

  172. Taylor F, Wright M, Zhu M (2012) Hemiarthroplasty of the hip with and without cement: a randomized clinical trial. J Bone Joint Surg Am 94:577–583. https://doi.org/10.2106/JBJS.K.00006

    Article  PubMed  Google Scholar 

  173. Lennox IA, McLauchlan J (1993) Comparing the mortality and morbidity of cemented and uncemented hemiarthroplasties. Injury 24:185–186. https://doi.org/10.1016/0020-1383(93)90290-m

    Article  CAS  PubMed  Google Scholar 

  174. Biber R, Brem M, Singler K et al (2012) Dorsal versus transgluteal approach for hip hemiarthroplasty: an analysis of early complications in seven hundred and four consecutive cases. Int Orthop (SICOT) 36:2219–2223. https://doi.org/10.1007/s00264-012-1624-4

    Article  Google Scholar 

  175. Sköldenberg O, Ekman A, Salemyr M et al (2010) Reduced dislocation rate after hip arthroplasty for femoral neck fractures when changing from posterolateral to anterolateral approach. Acta Orthop 81:583–587. https://doi.org/10.3109/17453674.2010.519170

    Article  PubMed  PubMed Central  Google Scholar 

  176. Authen AL, Dybvik E, Furnes O et al (2018) Surgeon’s experience level and risk of reoperation after hip fracture surgery: an observational study on 30,945 patients in the Norwegian Hip Fracture Register 2011–2015. Acta Orthop 89:496–502. https://doi.org/10.1080/17453674.2018.1481588

    Article  PubMed  PubMed Central  Google Scholar 

  177. Fung W, Jonsson A, Buhren V et al (2007) Classifying intertrochanteric fractures of the proximal femur: does experience matter? Med Princ Pract 16:198–202. https://doi.org/10.1159/000100390

    Article  PubMed  Google Scholar 

  178. Malik AT, Panni UY, Masri BA et al (2018) The impact of surgeon volume and hospital volume on postoperative mortality and morbidity after hip fractures: a systematic review. Int J Surg 54:316–327. https://doi.org/10.1016/j.ijsu.2017.10.072

    Article  PubMed  Google Scholar 

  179. Toh EM, Sahni V, Acharya A et al (2004) Management of intracapsular femoral neck fractures in the elderly; is it time to rethink our strategy? Injury 35:125–129. https://doi.org/10.1016/s0020-1383(02)00422-9

    Article  CAS  PubMed  Google Scholar 

  180. Pioli G, Giusti A, Barone A (2008) Orthogeriatric care for the elderly with hip fractures: where are we? Aging Clin Exp Res 20:113–122. https://doi.org/10.1007/BF03324757

    Article  PubMed  Google Scholar 

  181. Maxwell L, White S (2013) Anaesthetic management of patients with hip fractures: an update. CEACPP 13:179–183. https://doi.org/10.1093/bjaceaccp/mkt006

    Article  Google Scholar 

  182. Foss NB, Kehlet H (2006) Hidden blood loss after surgery for hip fracture. J Bone Joint Surg Br 88:1053–1059. https://doi.org/10.1302/0301-620X.88B8.17534

    Article  CAS  PubMed  Google Scholar 

  183. Mattisson L, Lapidus LJ, Enocson A (2018) What is the influence of a delay to surgery >24 hours on the rate of red blood cell transfusion in elderly patients with intertrochanteric or subtrochanteric hip fractures treated with cephalomedullary nails? J Orthop Trauma 32:403–407. https://doi.org/10.1097/BOT.0000000000001183

    Article  PubMed  Google Scholar 

  184. Carson JL, Terrin ML, Noveck H et al (2011) Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med 365:2453–2462. https://doi.org/10.1056/NEJMoa1012452

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  185. Brunskill SJ, Millette SL, Shokoohi A et al (2015) Red blood cell transfusion for people undergoing hip fracture surgery. Cochrane Database Syst Rev 4:CD009699. https://doi.org/10.1002/14651858.CD009699.pub2

    Article  Google Scholar 

  186. Zhu C, Yin J, Wang B et al (2019) Restrictive versus liberal strategy for red blood-cell transfusion in hip fracture patients: a systematic review and meta-analysis. Medicine (Baltimore) 98:e16795. https://doi.org/10.1097/MD.0000000000016795

    Article  Google Scholar 

  187. Yoon B-H, Lee BS, Won H et al (2019) Preoperative iron supplementation and restrictive transfusion strategy in hip fracture surgery. Clin Orthop Surg 11:265–269. https://doi.org/10.4055/cios.2019.11.3.265

    Article  PubMed  PubMed Central  Google Scholar 

  188. Farrow LS, Smith TO, Ashcroft GP et al (2016) A systematic review of tranexamic acid in hip fracture surgery. Br J Clin Pharmacol 82:1458–1470. https://doi.org/10.1111/bcp.13079

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  189. Kristensen PK, Thillemann TM, Søballe K et al (2016) Are process performance measures associated with clinical outcomes among patients with hip fractures? A population-based cohort study. Int J Qual Health Care 28:698–708. https://doi.org/10.1093/intqhc/mzw093

    Article  PubMed  Google Scholar 

  190. Chudyk AM, Jutai JW, Petrella RJ et al (2009) Systematic review of hip fracture rehabilitation practices in the elderly. Arch Phys Med Rehabil 90:246–262. https://doi.org/10.1016/j.apmr.2008.06.036

    Article  PubMed  Google Scholar 

  191. Baer M, Neuhaus V, Pape HC et al (2019) Influence of mobilization and weight bearing on in-hospital outcome in geriatric patients with hip fractures. SICOT-J 5:4. https://doi.org/10.1051/sicotj/2019005

    Article  PubMed  PubMed Central  Google Scholar 

  192. Lems WF, Dreinhöfer KE, Bischoff-Ferrari H et al (2017) EULAR/EFORT recommendations for management of patients older than 50 years with a fragility fracture and prevention of subsequent fractures. Ann Rheum Dis 76:802–810. https://doi.org/10.1136/annrheumdis-2016-210289

    Article  CAS  PubMed  Google Scholar 

  193. Su B, Newson R, Soljak H et al (2018) Associations between post-operative rehabilitation of hip fracture and outcomes: national database analysis. BMC Musculoskelet Dis 19:211. https://doi.org/10.1186/s12891-018-2093-8

    Article  Google Scholar 

  194. Frenkel Rutenberg T, Vitenberg M, Haviv B et al (2018) Timing of physiotherapy following fragility hip fracture: delays cost lives. Arch Orthop Trauma Surg 138:1519–1524. https://doi.org/10.1007/s00402-018-3010-1

    Article  PubMed  Google Scholar 

  195. Roberts KC, Brox WT, Jevsevar DS et al (2015) Management of hip fractures in the elderly. J Am Acad Orthop Surg 23:131–137. https://doi.org/10.5435/JAAOS-D-14-00432

    Article  PubMed  Google Scholar 

  196. Pfeufer D, Zeller A, Mehaffey S et al (2019) Weight-bearing restrictions reduce postoperative mobility in elderly hip fracture patients. Arch Orthop Trauma Surg 139:1253–1259. https://doi.org/10.1007/s00402-019-03193-9

    Article  PubMed  Google Scholar 

  197. Kammerlander C, Pfeufer D, Lisitano LA et al (2018) Inability of older adult patients with hip fracture to maintain postoperative weight-bearing restrictions. J Bone Joint Surg Am 100:936–941. https://doi.org/10.2106/JBJS.17.01222

    Article  PubMed  Google Scholar 

  198. Diong J, Allen N, Sherrington C (2016) Structured exercise improves mobility after hip fracture: a meta-analysis with meta-regression. Br J Sports Med 50:346–355. https://doi.org/10.1136/bjsports-2014-094465

    Article  PubMed  Google Scholar 

  199. Wu J, Mao L, Wu J (2019) Efficacy of balance training for hip fracture patients: a meta-analysis of randomized controlled trials. J Orthop Surg Res 14:83. https://doi.org/10.1186/s13018-019-1125-x

    Article  PubMed  PubMed Central  Google Scholar 

  200. Ponten JB, Krug E, van Baardewijk LJ et al (2015) Intensive rehabilitation in selected hip fracture patients may optimize care efficiency: a retrospective comparison study. J Rehabil Med 47:278–281. https://doi.org/10.2340/16501977-1917

    Article  PubMed  Google Scholar 

  201. Kimmel LA, Liew SM, Sayer JM et al (2016) HIP4Hips (high intensity physiotherapy for hip fractures in the acute hospital setting): a randomised controlled trial. Med J Aust 205:73–78. https://doi.org/10.5694/mja16.00091

    Article  PubMed  Google Scholar 

  202. Hasebe K, Momosaki R, Sawabe M et al (2018) Effectiveness of weekend physical rehabilitation for functional recovery in geriatric patients with hip fracture. Geriatr Gerontol Int 18:1143–1146. https://doi.org/10.1111/ggi.13326

    Article  PubMed  Google Scholar 

  203. Huusko TM, Karppi P, Avikainen V et al (2000) Randomised, clinically controlled trial of intensive geriatric rehabilitation in patients with hip fracture: subgroup analysis of patients with dementia. BMJ 321:1107–1111. https://doi.org/10.1136/bmj.321.7269.1107

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  204. Allen J, Koziak A, Buddingh S et al (2012) Rehabilitation in patients with dementia following hip fracture: a systematic review. Physiother Can 64:190–201. https://doi.org/10.3138/ptc.2011-06BH

    Article  PubMed  PubMed Central  Google Scholar 

  205. Muir SW, Yohannes AM (2009) The impact of cognitive impairment on rehabilitation outcomes in elderly patients admitted with a femoral neck fracture: a systematic review. J Geriatr Phys Ther 32:24–32. https://doi.org/10.1519/00139143-200932010-00006

    Article  PubMed  Google Scholar 

  206. Smith TO, Gilbert AW, Sreekanta A et al (2020) Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery. Cochrane Database Syst Rev 2:CD010569. https://doi.org/10.1002/14651858.CD010569.pub3

    Article  PubMed  Google Scholar 

  207. Tedesco D, Gibertoni D, Rucci P et al (2018) Impact of rehabilitation on mortality and readmissions after surgery for hip fracture. BMC Health Serv Res 18:701. https://doi.org/10.1186/s12913-018-3523-x

    Article  PubMed  PubMed Central  Google Scholar 

  208. Pitzul KB, Wodchis WP, Carter MW et al (2016) Post-acute pathways among hip fracture patients: a system-level analysis. BMC Health Serv Res 16:275. https://doi.org/10.1186/s12913-016-1524-1

    Article  PubMed  PubMed Central  Google Scholar 

  209. Edgren J, Salpakoski A, Sihvonen SE et al (2015) Effects of a home-based physical rehabilitation program on physical disability after hip fracture: a randomized controlled trial. J Am Med Dir Assoc 16:350.e1-350. https://doi.org/10.1016/j.jamda.2014.12.015

    Article  Google Scholar 

  210. Turunen K, Salpakoski A, Edgren J et al (2017) Physical activity after a hip fracture: effect of a multicomponent home-based rehabilitation program—a secondary analysis of a randomized controlled trial. Arch Phys Med Rehabil 98:981–988. https://doi.org/10.1016/j.apmr.2017.01.004

    Article  PubMed  Google Scholar 

  211. Crotty M, Whitehead C, Miller M et al (2003) Patient and caregiver outcomes 12 months after home-based therapy for hip fracture: a randomized controlled trial. Arch Phys Med Rehabil 84:1237–1239. https://doi.org/10.1016/S0003-9993(03)00141-2

    Article  PubMed  Google Scholar 

  212. Zidén L, Kreuter M, Frändin K (2010) Long-term effects of home rehabilitation after hip fracture—1-year follow-up of functioning, balance confidence, and health-related quality of life in elderly people. Disabil Rehabil 32:18–32. https://doi.org/10.3109/09638280902980910

    Article  PubMed  Google Scholar 

  213. Salpakoski A, Törmäkangas T, Edgren J et al (2014) Effects of a multicomponent home-based physical rehabilitation program on mobility recovery after hip fracture: a randomized controlled trial. J Am Med Dir Assoc 15:361–368. https://doi.org/10.1016/j.jamda.2013.12.083

    Article  PubMed  Google Scholar 

  214. Huang T-T, Liang S-H (2005) A randomized clinical trial of the effectiveness of a discharge planning intervention in hospitalized elders with hip fracture due to falling. J Clin Nurs 14:1193–1201. https://doi.org/10.1111/j.1365-2702.2005.01260.x

    Article  PubMed  Google Scholar 

  215. Henke RM, Karaca Z, Jackson P et al (2017) Discharge planning and hospital readmissions. Med Care Res Rev 74:345–368. https://doi.org/10.1177/1077558716647652

    Article  PubMed  Google Scholar 

  216. Mine Y, Fujino Y, Sabanai K et al (2020) Effectiveness of regional clinical pathways on postoperative length of stay for hip fracture patients: a retrospective observational study using the Japanese diagnosis procedure combination database. J Orthop Sci 25:127–131. https://doi.org/10.1016/j.jos.2019.02.002

    Article  PubMed  Google Scholar 

  217. Lockwood KJ, Harding KE, Boyd JN et al (2019) Predischarge home visits after hip fracture: a randomized controlled trial. Clin Rehabil 33:681–692. https://doi.org/10.1177/0269215518823256

    Article  PubMed  Google Scholar 

  218. Lockwood KJ, Harding KE, Boyd JN et al (2020) Home visits by occupational therapists improve adherence to recommendations: process evaluation of a randomised controlled trial. Aust Occup Ther J 67:287–296. https://doi.org/10.1111/1440-1630.12651

    Article  PubMed  Google Scholar 

  219. Bishop S, Waring J (2019) From boundary object to boundary subject; the role of the patient in coordination across complex systems of care during hospital discharge. Soc Sci Med 235:112370. https://doi.org/10.1016/j.socscimed.2019.112370

    Article  PubMed  Google Scholar 

  220. Gordon AL, Evans BJ, Dhesi J (2017) The physician’s role in perioperative management of older patients undergoing surgery. Clin Med 17:357–359. https://doi.org/10.7861/clinmedicine.17-4-357

    Article  Google Scholar 

  221. Waring J, Bishop S, Marshall F et al (2019) An ethnographic study comparing approaches to inter-professional knowledge sharing and learning in discharge planning and care transitions. J Health Organ Manag 33:677–694. https://doi.org/10.1108/JHOM-10-2018-0302

    Article  PubMed  Google Scholar 

  222. Sanclemente-Boli T, Ponce-Ruiz S, Álvarez-Lorenzo C et al (2019) Effectiveness of a multidisciplinary educational intervention in patients with hip fracture: SWEET HOME study. Med Clin (Barc) 153:446–453. https://doi.org/10.1016/j.medcli.2019.02.026

    Article  Google Scholar 

  223. Tsui K, Fleig L, Langford DP et al (2015) Exploring older adults’ perceptions of a patient-centered education manual for hip fracture recovery: ‘everything in one place.’ Patient Prefer Adherence 9:1637–1645. https://doi.org/10.2147/PPA.S86148

    Article  PubMed  PubMed Central  Google Scholar 

  224. Vaculík J, Stepan JJ, Dungl P et al (2017) Secondary fracture prevention in hip fracture patients requires cooperation from general practitioners. Arch Osteoporos 12:49. https://doi.org/10.1007/s11657-017-0346-z

    Article  PubMed  Google Scholar 

  225. Storm M, Siemsen IMD, Laugaland K et al (2014) Quality in transitional care of the elderly: key challenges and relevant improvement measures. Int J Integr Care. https://doi.org/10.5334/ijic.1194

    Article  PubMed  PubMed Central  Google Scholar 

  226. Asplin G, Carlsson G, Zidén L et al (2017) Early coordinated rehabilitation in acute phase after hip fracture—a model for increased patient participation. BMC Geriatr 17:240. https://doi.org/10.1186/s12877-017-0640-z

    Article  PubMed  PubMed Central  Google Scholar 

  227. Lee J-A, Donaldson J, Drake D et al (2014) Venous thromboembolism knowledge among older post-hip fracture patients and their caregivers. Geriatr Nurs 35:374–380. https://doi.org/10.1016/j.gerinurse.2014.05.004

    Article  PubMed  PubMed Central  Google Scholar 

  228. Bergqvist D, Arcelus JI, Felicissimo P et al (2012) Post-discharge compliance to venous thromboembolism prophylaxis in high-risk orthopaedic surgery: results from the ETHOS registry. Thromb Haemost 107:280–287. https://doi.org/10.1160/TH11-07-0464

    Article  CAS  PubMed  Google Scholar 

  229. Bell JJ, Geirsdóttir ÓG, Hertz K et al (2021) Nutritional care of the older patient with fragility fracture: opportunities for systematised, interdisciplinary approaches across acute care, rehabilitation and secondary prevention settings. In: Falaschi P, Marsh D (eds) Orthogeriatrics: the management of older patients with fragility fractures. Springer International Publishing, Cham, pp 311–329

    Chapter  Google Scholar 

  230. Yu-Yahiro JA, Resnick B, Orwig D et al (2009) Design and implementation of a home-based exercise program post-hip fracture: the Baltimore hip studies experience. PM R 1:308–318. https://doi.org/10.1016/j.pmrj.2009.02.008

    Article  PubMed  PubMed Central  Google Scholar 

  231. Latham NK, Harris BA, Bean JF et al (2014) Effect of a home-based exercise program on functional recovery following rehabilitation after hip fracture: a randomized clinical trial. JAMA 311:700–708. https://doi.org/10.1001/jama.2014.469

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  232. Vrignaud A, Pelletier S, Dernis E et al (2018) Improvement in the primary and secondary prevention of osteoporosis by a fracture liaison service: feedback from a single French center care pathway. Arch Osteoporos 13:110. https://doi.org/10.1007/s11657-018-0523-8

    Article  PubMed  Google Scholar 

  233. Switzer JA, Jaglal S, Bogoch ER (2009) Overcoming barriers to osteoporosis care in vulnerable elderly patients with hip fractures. J Orthop Trauma 23:454–459. https://doi.org/10.1097/BOT.0b013e31815e92d2

    Article  PubMed  Google Scholar 

  234. Gardner MJ, Brophy RH, Demetrakopoulos D et al (2005) Interventions to improve osteoporosis treatment following hip fracture. A prospective, randomized trial. J Bone Joint Surg Am 87:3–7. https://doi.org/10.2106/JBJS.D.02289

    Article  PubMed  Google Scholar 

  235. Roberts JL, Pritchard AW, Williams M et al (2018) Mixed methods process evaluation of an enhanced community-based rehabilitation intervention for elderly patients with hip fracture. BMJ Open 8:e021486. https://doi.org/10.1136/bmjopen-2018-021486

    Article  PubMed  PubMed Central  Google Scholar 

  236. Kanis JA, Johnell O, De Laet C et al (2004) A meta-analysis of previous fracture and subsequent fracture risk. Bone 35:375–382. https://doi.org/10.1016/j.bone.2004.03.024

    Article  CAS  PubMed  Google Scholar 

  237. Colón-Emeric C, Kuchibhatla M, Pieper C et al (2003) The contribution of hip fracture to risk of subsequent fractures: data from two longitudinal studies. Osteoporos Int 14:879–883. https://doi.org/10.1007/s00198-003-1460-x

    Article  PubMed  Google Scholar 

  238. Klotzbuecher CM, Ross PD, Landsman PB et al (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15:721–739. https://doi.org/10.1359/jbmr.2000.15.4.721

    Article  CAS  PubMed  Google Scholar 

  239. Boonen S, Autier P, Barette M et al (2004) Functional outcome and quality of life following hip fracture in elderly women: a prospective controlled study. Osteoporos Int 15:87–94. https://doi.org/10.1007/s00198-003-1515-z

    Article  PubMed  Google Scholar 

  240. Brainsky A, Glick H, Lydick E et al (1997) The economic cost of hip fractures in community-dwelling older adults: a prospective study. J Am Geriatr Soc 45:281–287. https://doi.org/10.1111/j.1532-5415.1997.tb00941.x

    Article  CAS  PubMed  Google Scholar 

  241. Lyles KW, Colón-Emeric CS, Magaziner JS et al (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809. https://doi.org/10.1056/NEJMoa074941

    Article  CAS  PubMed  Google Scholar 

  242. Wells GA, Cranney A, Peterson J et al (2008) Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women. Cochrane Database Syst Rev 1:CD001155. https://doi.org/10.1002/14651858.CD001155.pub2

    Article  Google Scholar 

  243. Díez-Pérez A, Marin F, Eriksen EF et al (2019) Effects of teriparatide on hip and upper limb fractures in patients with osteoporosis: a systematic review and meta-analysis. Bone 120:1–8. https://doi.org/10.1016/j.bone.2018.09.020

    Article  CAS  PubMed  Google Scholar 

  244. Murad MH, Drake MT, Mullan RJ et al (2012) Clinical review. Comparative effectiveness of drug treatments to prevent fragility fractures: a systematic review and network meta-analysis. J Clin Endocrinol Metab 97:1871–1880. https://doi.org/10.1210/jc.2011-3060

    Article  CAS  PubMed  Google Scholar 

  245. Malouf-Sierra J, Tarantino U, García-Hernández PA et al (2017) Effect of teriparatide or risedronate in elderly patients with a recent pertrochanteric hip fracture: final results of a 78-week randomized clinical trial. J Bone Miner Res 32:1040–1051. https://doi.org/10.1002/jbmr.3067

    Article  CAS  PubMed  Google Scholar 

  246. Conley RB, Adib G, Adler RA et al (2020) Secondary fracture prevention: consensus clinical recommendations from a multistakeholder coalition. J Bone Miner Res 35:36–52. https://doi.org/10.1002/jbmr.3877

    Article  PubMed  Google Scholar 

  247. Zhao J-G, Zeng X-T, Wang J et al (2017) Association between calcium or vitamin D supplementation and fracture incidence in community-dwelling older adults: a systematic review and meta-analysis. JAMA 318:2466–2482. https://doi.org/10.1001/jama.2017.19344

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  248. Handoll HH, Sherrington C, Mak JC (2011) Interventions for improving mobility after hip fracture surgery in adults. Cochrane Database Syst Rev 3:CD001704. https://doi.org/10.1002/14651858.CD001704.pub4

    Article  Google Scholar 

  249. van Ooijen MW, Roerdink M, Trekop M et al (2016) The efficacy of treadmill training with and without projected visual context for improving walking ability and reducing fall incidence and fear of falling in older adults with fall-related hip fracture: a randomized controlled trial. BMC Geriatr 16:215. https://doi.org/10.1186/s12877-016-0388-x

    Article  PubMed  PubMed Central  Google Scholar 

  250. Javaid MK, Kyer C, Mitchell PJ et al (2015) Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool. Osteoporos Int 26:2573–2578. https://doi.org/10.1007/s00198-015-3192-0

    Article  CAS  PubMed  Google Scholar 

  251. Mitchell P, Åkesson K, Chandran M et al (2016) Implementation of models of care for secondary osteoporotic fracture prevention and orthogeriatric models of care for osteoporotic hip fracture. Best Pract Res Clin Rheumatol 30:536–558. https://doi.org/10.1016/j.berh.2016.09.008

    Article  PubMed  Google Scholar 

  252. Fracture Liaison Services, capture the fracture, International Osteoporosis Foundation. https://www.capturethefracture.org/fracture-liaison-services. Accessed 12 Apr 2021

  253. Ambrose AF, Paul G, Hausdorff JM (2013) Risk factors for falls among older adults: a review of the literature. Maturitas 75:51–61. https://doi.org/10.1016/j.maturitas.2013.02.009

    Article  PubMed  Google Scholar 

  254. Bilik O, Damar HT, Karayurt O (2017) Fall behaviors and risk factors among elderly patients with hip fractures. Acta Paul Enferm 30:420–427. https://doi.org/10.1590/1982-0194201700062

    Article  Google Scholar 

  255. Panel on Prevention of Falls in Older Persons, American Geriatrics Society and British Geriatrics Society (2011) Summary of the updated American Geriatrics Society/British Geriatrics Society clinical practice guideline for prevention of falls in older persons. J Am Geriatr Soc 59:148–157. https://doi.org/10.1111/j.1532-5415.2010.03234.x

    Article  Google Scholar 

  256. Yoo JI, Lee YK, Koo KH et al (2018) Concerns for older adult patients with acute hip fracture. Yonsei Med J 59:1240–1244. https://doi.org/10.3349/ymj.2018.59.10.1240

    Article  PubMed  PubMed Central  Google Scholar 

  257. Bower ES, Wetherell JL, Petkus AJ et al (2020) Neuroticism predicts fear of falling after hip fracture. Int J Geriatr Psychiatry 35:498–506. https://doi.org/10.1002/gps.5261

    Article  PubMed  Google Scholar 

  258. Bower ES, Wetherell JL, Petkus AJ et al (2016) Fear of falling after hip fracture: prevalence, course, and relationship with one-year functional recovery. Am J Geriatr Psychiatry 24:1228–1236. https://doi.org/10.1016/j.jagp.2016.08.006

    Article  PubMed  PubMed Central  Google Scholar 

  259. Gillespie LD, Robertson MC, Gillespie WJ et al (2012) Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev 9:CD007146. https://doi.org/10.1002/14651858.CD007146.pub3

    Article  Google Scholar 

  260. Sherrington C, Michaleff ZA, Fairhall N et al (2017) Exercise to prevent falls in older adults: an updated systematic review and meta-analysis. Br J Sports Med 51:1749–1757. https://doi.org/10.1136/bjsports-2016-096547

    Article  Google Scholar 

  261. Silva RB, Eslick GD, Duque G (2013) Exercise for falls and fracture prevention in long term care facilities: a systematic review and meta-analysis. J Am Med Dir Assoc 14:685-689.e2. https://doi.org/10.1016/j.jamda.2013.05.015

    Article  PubMed  Google Scholar 

  262. Davies EC, Green CF, Mottram DR et al (2008) The use of opioids and laxatives, and incidence of constipation, in patients requiring neck-of-femur (NOF) surgery: a pilot study. J Clin Pharm Ther 33:561–566. https://doi.org/10.1111/j.1365-2710.2008.00949.x

    Article  CAS  PubMed  Google Scholar 

  263. Trads M, Pedersen PU (2015) Constipation and defecation pattern the first 30 days after hip fracture. Int J Nurs Pract 21:598–604. https://doi.org/10.1111/ijn.12312

    Article  PubMed  Google Scholar 

  264. Trads M, Deutch SR, Pedersen PU (2018) Supporting patients in reducing postoperative constipation: fundamental nursing care—a quasi-experimental study. Scand J Caring Sci 32:824–832. https://doi.org/10.1111/scs.12513

    Article  PubMed  Google Scholar 

  265. Munch L, Tvistholm N, Trosborg I et al (2016) Living with constipation—older people’s experiences and strategies with constipation before and during hospitalization. Int J Qual Stud Health Well-being 11:30732. https://doi.org/10.3402/qhw.v11.30732

    Article  PubMed  Google Scholar 

  266. Neighbour C (2014) Improving bowel care after surgery for hip fracture. Nurs Older People 26:16–22. https://doi.org/10.7748/nop.26.10.16.e649

    Article  PubMed  Google Scholar 

  267. Love AL, Cornwell PL, Whitehouse SL (2013) Oropharyngeal dysphagia in an elderly post-operative hip fracture population: a prospective cohort study. Age Ageing 42:782–785. https://doi.org/10.1093/ageing/aft037

    Article  PubMed  Google Scholar 

  268. Beric E, Smith R, Phillips K et al (2019) Swallowing disorders in an older fractured hip population. Aust J Rural Health 27:304–310. https://doi.org/10.1111/ajr.12512

    Article  PubMed  Google Scholar 

  269. Byun S-E, Kwon KB, Kim SH et al (2019) The prevalence, risk factors and prognostic implications of dysphagia in elderly patients undergoing hip fracture surgery in Korea. BMC Geriatr 19:356. https://doi.org/10.1186/s12877-019-1382-x

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  270. Suiter DM, Leder SB (2008) Clinical utility of the 3-ounce water swallow test. Dysphagia 23:244–250. https://doi.org/10.1007/s00455-007-9127-y

    Article  PubMed  Google Scholar 

  271. Wilkinson AH, Burns SL, Witham MD (2012) Aspiration in older patients without stroke: a systematic review of bedside diagnostic tests and predictors of pneumonia. Eur Geriatr Med 3:145–152. https://doi.org/10.1016/j.eurger.2012.02.004

    Article  Google Scholar 

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Acknowledgements

Editorial assistance in the preparation of this paper was provided by Editamed srl, Torino, Italy.

Funding

This work, including travel and meeting expenses, was supported by an unrestricted grant from MSD Italia Srl. The sponsor had no role in selecting the participants, reviewing the literature, defining consensus statements, drafting or reviewing the paper, or in the decision to submit the manuscript. All views expressed are solely those of the authors.

Author information

Authors and Affiliations

  1. Unit of Internal Medicine and Geriatrics, Università Campus Bio-Medico di Roma, 00128, Rome, Italy

    Antonio De Vincentis & Raffaele Antonelli Incalzi

  2. Operative Unit of Anesthesia and Resuscitation, Hospital of Camposampiero, Padua, Italy

    Astrid Ursula Behr

  3. Acute Geriatric and Orthogeriatric Unit, S. Gerardo Hospital, Monza, Italy

    Giuseppe Bellelli

  4. Milano-Bicocca University, Milan, Italy

    Giuseppe Bellelli

  5. Physical and Rehabilitation Medicine Department, Campus Bio-Medico University of Rome, Rome, Italy

    Marco Bravi & Fabio Santacaterina

  6. Bachelor of Nursing, IRCCS SMN Fondazione Don Gnocchi, University of Milan, Milano, Italy

    Anna Castaldo

  7. Department of Cardiovascular, Endocrine-Metabolic Diseases and Ageing, Istituto Superiore di Sanità, Rome, Italy

    Lucia Galluzzo & Graziano Onder

  8. Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘Luigi Vanvitelli’, Naples, Italy

    Giovanni Iolascon & Marco Paoletta

  9. Institute of Neuroscience, Aging Branch, CNR, Padua, Italy

    Stefania Maggi

  10. Orthogeriatric Unit, Azienda Ospedaliero Universitaria di Modena, Ospedale Civile di Baggiovara, Modena, Italy

    Emilio Martini

  11. Orthopedic and Traumatology Unit, San Bortolo Hospital, Vicenza, Italy

    Alberto Momoli

  12. Orthopedy and Traumatology, Department of Health Sciences, San Paolo University Hospital, Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo, University of Milan Medical School, Milan, Italy

    Luca Pietrogrande

  13. Orthopedic and Traumatology Unit, ‘Maria Vittoria’ Hospital, Torino, Italy

    Mauro Roselli

  14. Società Italiana di Medicina Generale (SIMG), Firenze, Italy

    Mauro Ruggeri

  15. Orthogeriatric Unit, Geriatric Unit, Section of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, S. Maria della Misericordia Hospital, S. Andrea delle Fratte, Perugia, Italy

    Carmelinda Ruggiero

  16. Operative Unit of Anesthesia and Intensive Care Medicine, San Camillo-Forlanini Hospital, Rome, Italy

    Luigi Tritapepe

  17. Geriatric and Orthogeriatric Unit, Arcispedale S. Anna, University of Ferrara, Ferrara, Italy

    Amedeo Zurlo

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  1. Antonio De Vincentis
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  2. Astrid Ursula Behr
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  20. Raffaele Antonelli Incalzi
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Società Italiana Geriatria e Gerontologia (SIGG),

Associazione Italiana di Psicogeriatria (AIP),

Società Italiana di Geriatria Ospedale e Territorio (SIGOT),

Società Italiana di Medicina Generale (SIMG),

Società Italiana di Anestesia Analgesia Rianimazione e Terapia Intensiva (SIAARTI),

Società Italiana di Ortopedia e Traumatologia (SIOT),

Fragility Fracture Network-Italia (FFN-I),

Società Italiana di Medicina Fisica e Riabilitativa (SIMFER),

Società Italiana di Fisioterapia (SIF),

Consiglio Nazionale delle Ricerche (CNR),

Associazione Italiana di Fisioterapia (AIFI),

Istituto Superiore Sanità (ISS)

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Correspondence to Raffaele Antonelli Incalzi.

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ADV, AUB, GB, MB, AC, LG, GI, EM, AM, SM, GO, MP, LP, MR, MR, CR, FS, LT, AZ, and RAI report no conflict of interest related to the submitted work.

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De Vincentis, A., Behr, A.U., Bellelli, G. et al. Orthogeriatric co-management for the care of older subjects with hip fracture: recommendations from an Italian intersociety consensus. Aging Clin Exp Res 33, 2405–2443 (2021). https://doi.org/10.1007/s40520-021-01898-9

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