Detecting subtle mobility changes among older adults: the Quantitative Timed Up and Go test

Abstract

Background

The Quantitative Timed Up and Go (QTUG) test uses wearable sensors, containing a triaxial accelerometer and an add-on triaxial gyroscope, to quantify performance during the TUG test with potential to capture more minor changes in mobility.

Aims

To examine the responsiveness, minimum detectable change (MDC) and observed effect size of QTUG in a cohort of socially active adults aged 50 years and over participating in a structured community exercise program.

Methods

54 participants (91% females, mean age 63.6 ± 6.5 years) completed repeated QTUG testing under single- and dual-task conditions. Responsiveness of the QTUG was assessed by correlation of change in standard TUG with QTUG change (Pearson’s correlation coefficient). MDC and effect sizes (standardized mean difference and Cohen’s d) were also calculated for QTUG.

Results

There was a strong positive correlation between change in the standard TUG and change in QTUG (single task r = 0.91, p < 0.001). MDC in QTUG was calculated as 0.77 (Sd, 1.39; ICC 0.96) seconds (single task) and 2.33 (Sd 2.18; ICC 0.85) seconds (dual task). Several QTUG parameters showed improvements in mean values with small effect sizes (sit -to-stand transition time d = 0.418; walk time d = 0.398; cadence d = 0.306, swing time d = 0.314; step time d = 0.479; gait velocity d = 0.365; time to reach turn d = 0.322) under single-task conditions and with a moderate effect size (d = 0.549) in time taken to turn under the dual-task condition.

Conclusion

Initial evidence of QTUG’s responsiveness to change in mobility in active middle to older age adults has been demonstrated with small to moderate effect sizes observed in specific QTUG parameters.

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Data availability

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Acknowledgements

To all the Better Bones Program Participants who consented to be part of this study.

Funding

Nil.

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Affiliations

Authors

Contributions

Study Concept and Design: ES, CB; Data Acquisition: ES, CC, UMCP; Data Analysis: CB, ES; Data Interpretation: ES, CB, BG, CC, UMCP; Paper write up, Critical Revision and Approval: ES, CB, BG, CC, UMCP. The first draft of the paper was written by ES. All authors read and approved the final manuscript and agree to be accountable for all aspects of the work.

Corresponding author

Correspondence to Caitriona Cunningham.

Ethics declarations

Conflict of interest

B.R. Greene has a commercial interest in Kinesis Heath Technologies, the developers of the QTUG technology used in this study. Research was led by independent UCD researchers. BR Greene was not involved in data analysis. No funding provided.

Ethical approval

University College Dublin (UCD) Human Research Ethics Committee.

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Written consent of participants.

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Written consent of participants. This work has not been published in any previous journal. Related abstracts have been presented via oral presentation at conferences (eg. Irish Osteoporosis Society) but with no published conference proceedings or journal outputs.

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Cite this article

Smith, E., Cunningham, C., Greene, B.R. et al. Detecting subtle mobility changes among older adults: the Quantitative Timed Up and Go test. Aging Clin Exp Res (2020). https://doi.org/10.1007/s40520-020-01733-7

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Keywords

  • QTUG
  • Responsiveness
  • Aging
  • Exercise
  • Osteoporosis
  • Minimal detectable change