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Aging, fat mass, and prostate cancer: is it the time to reconsider testosterone?

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References

  1. Bhaskaran K, Douglas I, Forbes H et al (2014) Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults. Lancet 384:755–765. https://doi.org/10.1016/s0140-6736(14)60892-8

    Article  PubMed  PubMed Central  Google Scholar 

  2. Di Vincenzo A, Silvestrin V, Bertoli E et al (2018) Short-term effects of surgical weight loss after sleeve gastrectomy on sex steroids plasma levels and PSA concentration in men with severe obesity. Aging Male 17:1–5. https://doi.org/10.1080/13685538.2018.1528445

    Article  CAS  Google Scholar 

  3. Gómez-Gómez E, Carrasco-Valiente J, Campos-Hernández JP et al (2019) Clinical association of metabolic syndrome, C-reactive protein and testosterone levels with clinically significant prostate cancer. J Cell Mol Med 23:934–942. https://doi.org/10.1111/jcmm.13994

    Article  CAS  PubMed  Google Scholar 

  4. Duarte MF, Luis C, Baylina P et al (2018) Clinical and metabolic implications of obesity in prostate cancer: Is testosterone a missing link? Aging Male 24:1–13. https://doi.org/10.1080/13685538.2018.1519695

    Article  CAS  Google Scholar 

  5. Yassin A, Salman M, Talib RA et al (2017) Is there a protective role of testosterone against high-grade prostate cancer? Incidence and severity of prostate cancer in 553 patients who underwent prostate biopsy: a prospective data register. Aging Male 20:125–133. https://doi.org/10.1080/13685538.2017.1298584

    Article  CAS  PubMed  Google Scholar 

  6. Zhang X, Zhong Y, Saad F et al (2019) Testosterone therapy may reduce prostate cancer risk due to testosterone deficiency at a young age via stabilizing serum testosterone levels. Aging Male 12:1–7. https://doi.org/10.1080/13685538.2019.1578739

    Article  Google Scholar 

  7. Haider A, Zitzmann M, Doros G et al (2015) Incidence of prostate cancer in hypogonadal men receiving testosterone therapy: observations from 5-year median followup of 3 registries. J Urol 193:80–86. https://doi.org/10.1016/j.juro.2014.06.071

    Article  PubMed  Google Scholar 

  8. Kardoust Parizi M, Abufaraj M, Fajkovic H et al (2019) Oncological safety of testosterone replacement therapy in prostate cancer survivors after definitive local therapy: a systematic literature review and meta-analysis. Urol Oncol pii: S1078–1439:30236–30244. https://doi.org/10.1016/j.urolonc.2019.06.007

    Article  CAS  Google Scholar 

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Correspondence to Angelo Di Vincenzo.

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Di Vincenzo, A., El Hadi, H., Vettor, R. et al. Aging, fat mass, and prostate cancer: is it the time to reconsider testosterone?. Aging Clin Exp Res 32, 357–359 (2020). https://doi.org/10.1007/s40520-019-01372-7

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  • DOI: https://doi.org/10.1007/s40520-019-01372-7

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