Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation
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The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.
To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.
AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.
We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, − 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).
In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.
KeywordsArterial stiffness Atrial fibrillation CAVI Elderly Electric cardioversion Longitudinal strain
We thank Stefano Pedri, EE, and Angelo Sortezza, EE, by ESAOTE SpA (Italy), and Mrs. Yumiko Kato, by Fukuda Denshi (Japan), for their unconditioned help to the research project.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures were performed in accordance with the principles of the Declaration of Helsinki and approved by the appropriate institutional review committee.
All subjects gave their informed consent to participate in the study.
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