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Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

  • Stefano Fumagalli
  • Marta Migliorini
  • Simone Pupo
  • Irene Marozzi
  • Serena Boni
  • Alessandra Scardia
  • Alessandro Masi
  • Anna T. Roberts
  • Luigi Padeletti
  • Niccolò Marchionni
Short Communication
  • 28 Downloads

Abstract

Background

The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.

Aims

To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.

Methods

AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.

Results

We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, − 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).

Conclusions

In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

Keywords

Arterial stiffness Atrial fibrillation CAVI Elderly Electric cardioversion Longitudinal strain 

Notes

Acknowledgements

We thank Stefano Pedri, EE, and Angelo Sortezza, EE, by ESAOTE SpA (Italy), and Mrs. Yumiko Kato, by Fukuda Denshi (Japan), for their unconditioned help to the research project.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Human rights

All procedures were performed in accordance with the principles of the Declaration of Helsinki and approved by the appropriate institutional review committee.

Informed consent

All subjects gave their informed consent to participate in the study.

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Stefano Fumagalli
    • 1
  • Marta Migliorini
    • 1
  • Simone Pupo
    • 1
  • Irene Marozzi
    • 1
  • Serena Boni
    • 1
  • Alessandra Scardia
    • 1
  • Alessandro Masi
    • 1
  • Anna T. Roberts
    • 1
  • Luigi Padeletti
    • 2
    • 3
  • Niccolò Marchionni
    • 1
  1. 1.Geriatric Intensive Care Unit, Department of Experimental and Clinical MedicineUniversity of Florence and AOU CareggiFlorenceItaly
  2. 2.Electrophysiology Unit, Department of Experimental and Clinical MedicineUniversity of Florence and AOU CareggiFlorenceItaly
  3. 3.Cardiovascular DepartmentIRCCS MultiMedicaMilanItaly

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