Motivators for Alzheimer’s disease clinical trial participation

  • Shoshana H. Bardach
  • Sarah D. Holmes
  • Gregory A. Jicha
Short Communication

DOI: 10.1007/s40520-017-0771-2

Cite this article as:
Bardach, S.H., Holmes, S.D. & Jicha, G.A. Aging Clin Exp Res (2017). doi:10.1007/s40520-017-0771-2



Alzheimer’s disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations.


Participants, or their caregivers, from AD treatment and prevention CTs were surveyed about research motivators.


The 87 respondents had a mean age of 72.2, were predominantly Caucasian, 55.2% were male, and 56.3% had cognitive impairment. An overwhelming majority rated the potential to help themselves or a loved one and the potential to help others in the future as important motivators. Relatively few respondents were motivated by free healthcare, monetary rewards, or to make others happy.


Recruitment efforts should focus on the potential benefit for the individual, their loved ones, and others in the future rather than free healthcare or monetary rewards.


Clinical trials Motivation Recruitment 

Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Shoshana H. Bardach
    • 1
    • 2
  • Sarah D. Holmes
    • 3
  • Gregory A. Jicha
    • 2
    • 4
  1. 1.Graduate Center for Gerontology, College of Public HealthUniversity of KentuckyLexingtonUSA
  2. 2.Sanders-Brown Center on AgingUniversity of KentuckyLexingtonUSA
  3. 3.University of MarylandBaltimoreUSA
  4. 4.Department of NeurologyUniversity of KentuckyLexingtonUSA

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