Effect of low-intensity resistance training with heat stress on the HSP72, anabolic hormones, muscle size, and strength in elderly women

Abstract

Background

Several recent studies have reported that heat stress stimulates the activation of heat shock protein 72 (HSP72), leading to an increase in muscle synthesis. Some studies suggested that low-intensity resistance training combined with heat stress could improve muscle size and strength.

Aim

This study aimed to identify the effect of low-intensity resistance training with heat stress over 12 weeks on the HSP72, anabolic hormones, muscle size, and strength in elderly women.

Methods

The subjects were physically healthy women of 65–75 years, who were randomly assigned to one of three groups: a low-intensity resistance training with heating sheet group (HRT group, n = 8), a moderate-intensity resistance training (RT group, n = 6), and a heating sheet group (HEAT group, n = 7). Computed tomography scans, 1-repetition maximum (1RM), and blood samples were taken pre- and post-training.

Results

The HSP72 did not vary significantly between the different groups and times. The IGF-1 and 1RM had significantly increased in all three groups after the training (respectively, p < 0.05). Moreover, the cross-sectional area (CSA) of the quadriceps showed a significantly greater increase in the HRT group than in the HEAT group (p < 0.05).

Conclusions

We found that low-intensity training with heat stress stimulated the anabolic hormones of elderly women, improving their muscle strength and hypertrophy. We believe that low-intensity training with heat stress is an effective way to prevent muscle atrophy and to improve muscle strength in elderly women.

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Acknowledgements

This research was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korea Government (Ministry of Science, ICT & Future Planning) (No. 2015S1A5A2A01012405).

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Correspondence to Sung Jin Yoon.

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The authors declare that they have no conflict of interest.

Statement of human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the 1964 Helsinki Declaration and its later amendments. No studies with animals were performed.

Ethical approval

The study was approved by the Bioethics Committee (Institutional Review Board) of Korea University (KU-IRB-14-44-A-1) and complied with the standards set by the Declaration of Helsinki.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Yoon, S.J., Lee, M.J., Lee, H.M. et al. Effect of low-intensity resistance training with heat stress on the HSP72, anabolic hormones, muscle size, and strength in elderly women. Aging Clin Exp Res 29, 977–984 (2017). https://doi.org/10.1007/s40520-016-0685-4

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Keywords

  • Heat stress
  • Resistance training
  • HSP72
  • Anabolic hormones
  • Cross-sectional area