Aging Clinical and Experimental Research

, Volume 29, Issue 5, pp 1031–1037 | Cite as

Prescription of anti-osteoporosis medications after hospitalization for hip fracture: a multicentre Italian survey

  • Stefano Gonnelli
  • Carla Caffarelli
  • Giovanni Iolascon
  • Francesco Bertoldo
  • Giulia Letizia Mauro
  • Aurora Patti
  • Ranuccio Nuti
Original Article



Literature data indicate that the proportion of patients with recent hip fracture who receive a prescription for anti-osteoporotic drugs is low and does not seem to increase over time. This study aimed to obtain data on the prescription for anti-osteoporotic drugs in Italian patients discharged after a recent hip fracture and to assess which variables could have influenced the decision for prescribing osteoporosis medication.


A total of four Italian centres located in four different geographical areas (Siena, Verona, Naples and Palermo) participated in this retrospective study. In each centre, experienced clinicians gathered the data of up to 200 consecutive patients discharged after a recent low-trauma hip fracture. The analysis was carried out on 697 patients (540 women and 157 men; mean age 81.9 ± 8.6 years).


The percentage of patients who were receiving any type of treatment for osteoporosis before the hip fracture was 8.8% (ranging from 2.4% in Naples to 17.4% in Verona). After the index hip fracture, only 23.2% of patients (namely 10.5% of men and 27.2% of women) received prescription for any pharmacological treatments for osteoporosis. Both female gender and previous use of medications for osteoporosis were positively associated with the likelihood of receiving prescription for anti-osteoporotic treatment at discharge.


This study showed that less than 25% of the elderly Italian patients discharged after a hip fracture received a prescription for any type of treatment for osteoporosis and highlights the urgent need for implementing new strategies in the management of hip fracture patients.


Hip fracture Anti-osteoporotic drugs Comorbidities Ca/vitamin D supplements 


Compliance with ethical standards

Conflict of interest

Stefano Gonnelli, Carla Caffarelli, Giovanni Iolascon, Francesco Bertoldo, Giulia Letizia Mauro, Aurora Patti and Ranuccio Nuti declare that they have no conflict of interest.

Statement of human and animal rights

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration. Procedures performed in this study did not involve animals.

Informed consent

For this type of study formal consent is not required.


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Stefano Gonnelli
    • 1
  • Carla Caffarelli
    • 1
  • Giovanni Iolascon
    • 2
  • Francesco Bertoldo
    • 3
  • Giulia Letizia Mauro
    • 4
  • Aurora Patti
    • 1
  • Ranuccio Nuti
    • 1
  1. 1.Department of Medicine, Surgery and NeuroscienceUniversity of SienaSienaItaly
  2. 2.Department of Medical and Surgical Specialties and DentistrySecond University of NaplesNaplesItaly
  3. 3.Department of Medicine, and Department of Neurological Sciences and MovementUniversity of VeronaVeronaItaly
  4. 4.Department of Surgical and Oncology SciencesUniversity of PalermoPalermoItaly

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