Skip to main content
SpringerLink
Log in

Association of depression and sleep quality with complications of type 2 diabetes in geriatric patients

Aging Clinical and Experimental Research volume 27, pages 533–538 (2015)Cite this article

Abstract

Background

Diabetes mellitus (DM) is highly prevalent and increasing in geriatric population. Depression and sleep disorders occur at a higher rate in patients with diabetes compared with controls.

Aim

The purpose of this study was to demonstrate whether diabetic complications influence the sleep quality and depression in elderly patients.

Methods

154 geriatric diabetic patients (male/female: 69/85) were enrolled in this study. Patients were investigated for microvascular and macrovascular complications. The Pittsburgh Sleep Quality Index (PSQI) and Geriatric Depression Scale (GDS) were performed for assessment of sleep quality and depression, respectively. Linear regression analysis was performed to identify significant independent related factors for GDS and PSQI scores.

Results

Microvascular and macrovascular complications were found in 47.4 % and 29.2 of study population. PSQI and GDS scores of patients with microvascular complications were significantly higher than those of patients without microvascular complications (8.23 ± 3.83 vs 5.76 ± 3.04, p 0.001; 11.07 ± 6.07 vs 6.94 ± 5.35, p 0.001), respectively. There was no difference in GDS scores between the patients with and without macrovascular complications. There was a positive correlation between DM duration and PSQI, GDS scores. Neuropathy was an independent variable for poor sleep quality (OR 1.362, 95 % CI 0.032–2.692, p 0.045) and depression (OR 2.909, 95 % CI 0.610–5.209, p 0.014).

Conclusion

Depression status and sleep quality are strongly influenced by diabetic complications and DM duration in elderly patients.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

USD 39.95

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

References

  1. International Diabetes Federation (2013) IDF Diabetes Atlas, 6th edn. International Diabetes Federation, Brussels, Belgium. http://www.idf.org/diabetesatlas

  2. Zhang X, Decker FH, Luo H, Geiss LS, Pearson WS, Saaddine JB et al (2010) Trends in the prevalence and comorbidities of diabetes mellitus in nursing home residents in the United States: 1995–2004. J Am Geriatr Soc 58:724–730

    Article  PubMed  Google Scholar 

  3. Boyle JP, Honeycutt AA, Narayan KM, Hoerger TJ, Geiss LS, Chen H et al (2001) Projection of diabetes burden through 2050: impact of changing demography and disease prevalence in the U.S. Diabetes Care 24:1936–1940

    Article  CAS  PubMed  Google Scholar 

  4. Motta M, Bennati E, Cardillo E, Ferlito L, Passamonte M, Vacante M et al (2010) A combination of glycosylated hemoglobin, impaired fasting glucose and waist circumference is effective in screening for individuals at risk for future type 2 diabetes. Arch Gerontol Geriatr 50:105–109

    Article  CAS  PubMed  Google Scholar 

  5. Chiniwala N, Jabbour S (2011) Management of diabetes mellitus in the elderly. Curr Opin Endocrinol Diabetes Obes 18:148–152

    Article  PubMed  Google Scholar 

  6. Knutson KL (2010) Sleep duration and cardiometabolic risk: a review of the epidemiologic evidence. Best Pract Res Clin Endocrinol Metab 24:731–743

    Article  PubMed Central  PubMed  Google Scholar 

  7. Foley DJ, Monjan AA, Brown SL, Simonsick EM, Wallace RB, Blazer DG (1995) Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep 18:425–432

    CAS  PubMed  Google Scholar 

  8. Cooke JR, Ancoli-Israel S (2006) Sleep and its disorders in older adults. Psychiatr Clin North Am 29:1077–1093

    Article  PubMed  Google Scholar 

  9. Ancoli-Israel S (2005) Sleep and aging: prevalence of disturbed sleep and treatment considerations in older adults. J Clin Psychiatry 66(Suppl 9):24–30

    PubMed  Google Scholar 

  10. Poongothai S, Anjana RM, Pradeepa R, Ganesan A, Unnikrishnan R, Rema M et al (2011) Association of depression with complications of type 2 diabetes—the Chennai Urban Rural Epidemiology Study (CURES- 102). J Assoc Physicians India 59:644–648

    PubMed  Google Scholar 

  11. Kinder LS, Katon WJ, Ludman E, Russo J, Simon G, Lin EH et al (2006) Improving depression care in patients with diabetes and multiple complications. J Gen Intern Med 21:1036–1041

    Article  PubMed Central  PubMed  Google Scholar 

  12. Association AD (2009) Diagnosis and classification of diabetes mellitus. Diabetes Care 32(Suppl 1):S62–S67

    Article  Google Scholar 

  13. Farag YM, Al Wakeel JS (2011) Diabetic nephropathy in the Arab Gulf countries. Nephron Clin Pract 119:c317–c322 (discussion c22-3)

    Article  PubMed  Google Scholar 

  14. Ko SH, Cha BY (2012) Diabetic peripheral neuropathy in type 2 diabetes mellitus in Korea. Diabetes Metab J 36:6–12

    Article  PubMed Central  PubMed  Google Scholar 

  15. Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD, American Diabetes Association et al (2003) Diabetic retinopathy. Diabetes Care 26:226–229

    Article  PubMed  Google Scholar 

  16. Carpenter JS, Andrykowski MA (1998) Psychometric evaluation of the Pittsburgh Sleep Quality Index. J Psychosom Res 45:5–13

    Article  CAS  PubMed  Google Scholar 

  17. Agargun MY, Kara H, Anlar O (1996) The validity and reliability of the Pittsburgh Sleep Quality Index. Turk Psikiyatri Derg 7:107–115

    Google Scholar 

  18. Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28:193–213

    Article  CAS  PubMed  Google Scholar 

  19. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M et al (1982) Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 17:37–49

    Article  PubMed  Google Scholar 

  20. Ertan T, Eker E (2000) Reliability, validity, and factor structure of the geriatric depression scale in Turkish elderly: are there different factor structures for different cultures? Int Psychogeriatr 12:163–172

    Article  CAS  PubMed  Google Scholar 

  21. Knutson KL, Van Cauter E (2008) Associations between sleep loss and increased risk of obesity and diabetes. Ann NY Acad Sci 1129:287–304

    Article  PubMed Central  PubMed  Google Scholar 

  22. Knutson KL, Ryden AM, Mander BA, Van Cauter E (2006) Role of sleep duration and quality in the risk and severity of type 2 diabetes mellitus. Arch Intern Med 166:1768–1774

    Article  PubMed  Google Scholar 

  23. Cuellar NG, Ratcliffe SJ (2008) A comparison of glycemic control, sleep, fatigue, and depression in type 2 diabetes with and without restless legs syndrome. J Clin Sleep Med 4:50–56

    PubMed Central  PubMed  Google Scholar 

  24. Luyster FS, Dunbar-Jacob J (2011) Sleep quality and quality of life in adults with type 2 diabetes. Diabetes Educ 37:347–355

    Article  PubMed Central  PubMed  Google Scholar 

  25. Zelman DC, Brandenburg NA, Gore M (2006) Sleep impairment in patients with painful diabetic peripheral neuropathy. Clin J Pain 22:681–685

    Article  PubMed  Google Scholar 

  26. Raymann RJ, Swaab DF, Van Someren EJ (2008) Skin deep: enhanced sleep depth by cutaneous temperature manipulation. Brain 131:500–513

    Article  PubMed  Google Scholar 

  27. Sharma S, Oliver-Fernandez A, Liu W, Buchholz P, Walt J (2005) The impact of diabetic retinopathy on health-related quality of life. Curr Opin Ophthalmol 16:155–159

    Article  PubMed  Google Scholar 

  28. Devenney R, O’Neill S (2010) The experience of diabetic retinopathy: a qualitative study. Br J Health Psychol. doi:10.1348/2044-8287.002008

    Google Scholar 

  29. Coyne KS, Margolis MK, Kennedy-Martin T, Baker TM, Klein R, Paul MD et al (2004) The impact of diabetic retinopathy: perspectives from patient focus groups. Fam Pract 21:447–453

    Article  PubMed  Google Scholar 

  30. Scanlon PH, Martin ML, Bailey C, Johnson E, Hykin P, Keightley S (2006) Reported symptoms and quality-of-life impacts in patients having laser treatment for sight- threatening diabetic retinopathy. Diabet Med 23:60–66

    Article  CAS  PubMed  Google Scholar 

  31. Fenwick EK, Pesudovs K, Khadka J, Dirani M, Rees G, Wong TY et al (2012) The impact of diabetic retinopathy on quality of life: qualitative findings from an item bank development project. Qual Life Res 21:1771–1782

    Article  PubMed  Google Scholar 

  32. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Diabetes Prevention Program Research Group et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393–403

    Article  CAS  PubMed  Google Scholar 

  33. de Groot M, Anderson R, Freedland KE, Clouse RE, Lustman PJ (2001) Association of depression and diabetes complications: a meta-analysis. Psychosom Med 63:619–630

    Article  PubMed  Google Scholar 

  34. Lustman PJ, Griffith LS, Gavard JA, Clouse RE (1992) Depression in adults with diabetes. Diabetes Care 15:1631–1639

    Article  CAS  PubMed  Google Scholar 

  35. Lin EH, Rutter CM, Katon W, Heckbert SR, Ciechanowski P, Oliver MM et al (2010) Depression and advanced complications of diabetes: a prospective cohort study. Diabetes Care 33:264–269

    Article  PubMed Central  PubMed  Google Scholar 

  36. Golden SH, Lee HB, Schreiner PJ, Diez Roux A, Fitzpatrick AL, Szklo M et al (2007) Depression and type 2 diabetes mellitus: the multiethnic study of atherosclerosis. Psychosom Med 69:529–536

    Article  PubMed  Google Scholar 

  37. Kathol RG, Jaeckle RS, Lopez JF, Meller WH (1989) Pathophysiology of HPA axis abnormalities in patients with major depression: an update. Am J Psychiatry 146:311–317

    Article  CAS  PubMed  Google Scholar 

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

  1. Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Gaziantep University, 27100, Sahinbey, Gaziantep, Turkey

    Zeynel Abidin Öztürk & Yalçın Kepekçi

  2. Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Sihhiye, 06100, Ankara, Turkey

    Yusuf Yesil & Mehmet Emin Kuyumcu

  3. Department of Internal Medicine, Faculty of Medicine, Gaziantep University, 27100, Sahinbey, Gaziantep, Turkey

    Esen Savas, Özhan Uygun & Zeynel Abidin Sayıner

Authors
  1. Zeynel Abidin Öztürk
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yusuf Yesil
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mehmet Emin Kuyumcu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Esen Savas
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Özhan Uygun
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Zeynel Abidin Sayıner
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Yalçın Kepekçi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Zeynel Abidin Öztürk.

Rights and permissions

Reprints and Permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Öztürk, Z.A., Yesil, Y., Kuyumcu, M.E. et al. Association of depression and sleep quality with complications of type 2 diabetes in geriatric patients. Aging Clin Exp Res 27, 533–538 (2015). https://doi.org/10.1007/s40520-014-0293-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40520-014-0293-0

Keywords

search

Navigation