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Osseointegration in the elderly

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Abstract

Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to morphological and biological alterations in the proximal femur that adversely affect both mechanical stability of implant and biological response of bone, making it more challenging to achieve a valid osseointegration.

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References

  1. Brånemark P-I (1959) Vital microscopy of bone marrow in rabbit. Scand J Clin Lab Invest 11(Supp 38):1–82

    PubMed  Google Scholar 

  2. Brånemark R, Brånemark P-I, Rydevik B, Myers RR (2001) Osseointegration in skeletal reconstruction and rehabilitation: a review. J Rehabil Res Dev 38(2):175–181

    PubMed  Google Scholar 

  3. Worthington P (1997) History, development, and current status of osseointegration as revealed by experience in craniomaxillofacial surgery. In: Brånemark P-I, Rydevik BL, Skalak R (eds) Osseointegration in skeletal reconstruction and joint replacement. IL Quintessence Publishing Co, Carol Stream, pp 25–44

    Google Scholar 

  4. Mai KT, Verioti CA, Casey K, Slesarenko Y, Romeo L, Colwell CW Jr (2010) Cementless femoral fixation in total hip arthroplasty. Am J Orthop (Belle Mead NJ) 39(3):126–130

    Google Scholar 

  5. Engh CA, O’Connor D, Jasty M, McGovern TF, Bobyn JD, Harris WH (1992) Quantification of implant micromotion, strain shielding, and bone resorption with porous-coated anatomic medullary locking femoral prostheses. Clin Orthop Relat Res (285):13–29

  6. Khanuja HS, Vakil JJ, Goddard MS, Mont MA (2011) Cementless femoral fixation in total hip arthroplasty. J Bone Joint Surg Am 93(5):500–509

    Article  PubMed  Google Scholar 

  7. Ramamurti BS, Orr TE, Bragdon CR, Lowenstein JD, Jasty M, Harris WH (1997) Factors influencing stability at the interface between a porous surface and cancellous bone. J Biomed Mater Res 36(2):274–280

    Article  PubMed  CAS  Google Scholar 

  8. Yamada H, Yoshihara Y, Henmi O, Morita M, Shiromoto Y, Kawano T, Kanaji A, Ando K, Nakagawa M, Kosaki N, Fukaya E (2009) Cementless total hip replacement: past, present, and future. J Orthop Sci 14(2):228–241

    Article  PubMed  Google Scholar 

  9. Haddad RJ Jr, Cook SD, Thomas KA (1987) Biological fixation of porous-coated implants. J Bone Joint Surg Am 69:1459–1466

    PubMed  Google Scholar 

  10. Bobyn JD, Wilson GJ, MacGregor DC, Pilliar RM, Weatherly GC (1982) Effect of pore size on the peel strength of attachment of fibrous tissue to porous-surfaced implants. J Biomed Mater Res 16(5):571–584

    Article  PubMed  CAS  Google Scholar 

  11. Zatti G, Andrini L, Cherubino P, Di Nucci A (1997) Quantitative evaluation of the bone–metal interface in implants with two different surface roughnesses: an experimental study in rabbits. Surg Technol Int 6:385–388

    PubMed  CAS  Google Scholar 

  12. Noble PC, Box GG, Kamaric E, Fink MJ, Alexander JW, Tullos HS (1995) The effect of aging on the shape of the proximal femur. Clin Orthop Relat (316):31–44

  13. Aro HT, Alm JJ, Moritz N, Mäkinen TJ, Lankinen P (2012) Low BMD affects initial stability and delays stem osseointegration in cementless total hip arthroplasty in women: a 2-year RSA study of 39 patients. Acta Orthop 83(2):107–114

    Article  PubMed  Google Scholar 

  14. Moritz N, Alm JJ, Lankinen P, Mäkinen TJ, Mattila K, Aro HT (2011) Quality of intertrochanteric cancellous bone as predictor of femoral stem RSA migration in cementless total hip arthroplasty. J Biomech 44:221–227

    Article  PubMed  Google Scholar 

  15. Marsland D, Mears SC (2012) A review of periprosthetic femoral fractures associated with total hip arthroplasty. Geriatr Orthop Surg Rehabil 3(3):107–120

    Article  PubMed  Google Scholar 

  16. Bhandari M, Bajammal S, Guyatt GH, Griffith L, Busse JW, Schünemann H, Einhorn TA (2005) Effect of bisphosphonates on periprosthetic bone mineral density after total joint arthroplasty. A meta-analysis. J Bone Joint Surg Am 87(2):293–301

    Article  PubMed  Google Scholar 

  17. Maïmoun L, Brennan TC, Badoud I, Dubois-Ferriere V, Rizzoli R, Ammann P (2010) Strontium ranelate improves implant osseointegration. Bone 46(5):1436–1441

    Article  PubMed  Google Scholar 

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Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Authors and Affiliations

  1. Azienda Ospedaliera San Gerardo, Università degli Studi di Milano-Bicocca, Via Pergolesi, 33, 20900, Monza, Italy

    G. Piarulli, A. Rossi & G. Zatti

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  1. G. Piarulli
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  2. A. Rossi
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  3. G. Zatti
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Correspondence to G. Piarulli.

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Piarulli, G., Rossi, A. & Zatti, G. Osseointegration in the elderly. Aging Clin Exp Res 25 (Suppl 1), 59–60 (2013). https://doi.org/10.1007/s40520-013-0103-0

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  • DOI: https://doi.org/10.1007/s40520-013-0103-0

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