Abstract
Recent findings
Cocaine use plays a large role in initiating and maintaining homelessness.
Purpose of review
The present review systematically studied the existing literature on prevalence of cocaine use, cocaine use problems, and cocaine use disorders in the lives of homeless populations.
Summary
A total of 57 articles with 55 unique studies were included in the review. Cocaine use was quite prevalent in these homeless samples, with around one-third of samples endorsing lifetime use and one-fourth endorsing past year use. Further, prevalence rates for cocaine use problems ranged from around one-fourth to more than one-third across different measurement periods. The median prevalence rate for lifetime cocaine use disorder across studies was 30%. Comparatively, cocaine and cannabis had similar popularity for use, but cocaine was the dominant drug in studies assessing problematic use and disorders. In general, cocaine appeared to be more prevalent in the USA than internationally. Although this literature had methodological inconsistencies limiting comparisons across studies, the findings suggest a major role of cocaine in the initiation and maintenance of homelessness. Further research is needed, especially studies providing prevalence data in multiple time frames, studies comparing prevalence across specific subgroups, and prospective studies.
Similar content being viewed by others
References and Recommended Reading
Papers of particular interest, published recently, have been highlighted as: • Of importance
*Included in systematic review
U.N. Office of the High Commissioner Human Rights (OHCHR). Commission on Human Rights 61st session, E/CN.4/2005/48: Economic, Social and Cultural Rights. 2005. Available from: https://www.ohchr.org/en/special-procedures/sr-housing/annual-thematic-reports. Accessed 06/20/2022.
US Department of Housing and Urban Development (HUD). The 2016 Annual Homeless Assessment Report (AHAR) to Congress. 2016. https://www.hudexchange.info/resource/5178/2016-ahar-part-1-pit-estimates-of-homelessness/. Accessed 06/20/2022.
Nishio A, Horita R, Sado T, Mizutani S, Watanabe T, Uehara R, et al. Causes of homelessness prevalence: relationship between homelessness and disability. Psychiatry Clin Neurosci. 2016;71(3):180–8.
• Rukmana D. The causes of homelessness and the characteristics associated with high risk of homelessness: a review of intercity and intracity homelessness data. Hous Policy Debate. 2020;30(2):291–308. Available from: https://doi.org/10.1080/10511482.2019.1684334. Important review that compares homelessness measurement metrics and how those differences point to different causes of homelessness.
•* North CS, Eyrich KM, Pollio DE, Spitznagel EL. Are rates of psychiatric disorders in the homeless population changing? Am J Public Health. 2004;94(1):103–8. 30-year study on trends in cocaine use in homeless populations.
* Spinelli MA, Ponath C, Tieu L, Hurstak EE, Guzman D, Kushel M. Factors associated with substance use in older homeless adults: results from the HOPE HOME study. Subst Abus. 2017;38(1):88–94. Available from: https://doi.org/10.1080/08897077.2016.1264534.
Fazel S, Geddes JR, Kushel M. The health of homeless people in high-income countries: descriptive epidemiology, health consequences, and clinical and policy recommendations. Lancet. 2014;384(9953):1529–40. Available from: https://doi.org/10.1016/S0140-6736(14)61132-6.
Fazel S, Khosla V, Doll H, Geddes J. The prevalence of mental disorders among the homeless in Western countries: systematic review and meta-regression analysis. PLoS Med. 2008;5(12):1670–81.
* North CS, Eyrich-Garg KM, Pollio DE, Thirthalli J. A prospective study of substance use and housing stability in a homeless population. Soc Psychiatry Psychiatr Epidemiol. 2010;45(11):1055–62.
Chen KW, Banducci AN, Guller L, Macatee RJ, Lavelle A, Daughters SB, et al. An examination of psychiatric comorbidities as a function of gender and substance type within an inpatient substance use treatment program. Drug Alcohol Depend. 2011;118(2–3):92–9. https://doi.org/10.1016/j.drugalcdep.2011.03.003.
Karila L, Petit A, Lowenstein W, Reynaud M. Diagnosis and consequences of cocaine addiction. Curr Med Chem. 2012;19(33):5612–8.
North CS, Pollio DE. Financing cocaine use in a homeless population. Behav Sci (Basel). 2017;7(4):1–15.
Moher D, Liberati A, Tetzlaff J, Altman DG, Group TP. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):1–6.
Giannakopoulos NN, Rammelsberg P, Eberhard L, Schmitter M. A new instrument for assessing the quality of studies on prevalence. Clin Oral Invest. 2011;16:781–8.
Hoy D, Brooks P, Woolf A, Blyth F, March L, Bain C, et al. Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement. J Clin Epidemiol. 2012;65(9):934–9.
Macaulay S, Dunger DB, Norris SA. Gestational diabetes mellitus in Africa: a systematic review. PLoS ONE. 2014;9(6):1–11.
Rosário BDA, De Nazaré MDFS, Estadella D, Ribeiro DA, Viana MDB. Behavioral and neurobiological alterations induced by chronic use of crack cocaine. Rev Neurosci. 2019;31(1):59–75.
• Ryan SA. Cocaine use in adolescents and young adults. Pediatr Clin North Am. 2019;66(6):1135–47. Available from: https://doi.org/10.1016/j.pcl.2019.08.014. Recent overview of physiological effects of cocaine, evaluation for cocaine use disorder, and treatment strategies.
Haasen C, Krausz M. Myths versus evidence with respect to cocaine and crack: learning from the US experience. Eur Addict Res. 2001;7(4):159–60.
Butler AJ, Rehm J, Fischer B. Health outcomes associated with crack-cocaine use: systematic review and meta-analyses. Drug Alcohol Depend. 2017;180:401–16. Available from: https://doi.org/10.1016/j.drugalcdep.2017.08.036.
• Fischer B, Cruz MS, Bastos FI, Tyndall M. Crack across the Americas — a massive problem in continued search of viable answers: exemplary views from the North (Canada) and the South (Brazil). Int J Drug Policy. 2013;24(6):631–3. Available from: https://doi.org/10.1016/j.drugpo.2013.09.003. Meta-analysis of the health outcomes of cocaine.
North CS, Pollio DE, Smith EM, Spitznagel EL. Correlates of early onset and chronicity of homelessness in a large urban homeless population. J Nerv Ment Dis. 1998;186(7):393–400.
* Linn LS, Gelberg L, Leake B. Substance abuse and mental health status of homeless and domiciled low-income users of a medical clinic. Hosp Community Psychiatry. 1990;41(3):306–10.
* Johnson TP, Barrett ME. Substance use and treatment needs among homeless persons in cook county, Illinois. Subst Use Misuse. 1995;30(5):557–85.
* Spinner GF, Leaf PJ. Homelessness and drug abuse in New Haven. Hosp Community Psychiatry. 1992;43(2):166–8.
* Robertson MJ, Ziotnick C, Westerfelt A. Drug use disorders and treatment contact among homeless adults in Alameda County, California. Am J Public Health. 1997;87(2):221–32.
* Haugland G, Siegel C, Hopper K, Alexander MJ. Mental illness among homeless individuals in a Suburban County. Psychiatr Serv. 1997;48(4):504–9.
* VanGeest JB, Johnson TP. Substance use patterns among homeless migrants and nonmigrants in Chicago. Subst Use Misuse. 1997;32(7–8):877–907.
* D’Amore J, Hung O, Chiang W, Goldfrank L. The epidemiology of the homeless population and its impact on an urban emergency department. Acad Emerg Med. 2001;8(11):1051–5.
* Fisher B, Hovell M, Hofstetter CR, Hough R. Risks associated with long-term homelessness among women: battery, rape, and HIV infection. Int J Health Serv. 1995;25(2):351–69.
* Baumann BM, Mazzarelli A, Brunner J, Chansky ME, Thompson N, Boudreaux ED. Purchase and use patterns of heroin users at an inner-city emergency department. J Emerg Med. 2012;42(1):93–9. Available from: https://doi.org/10.1016/j.jemermed.2010.06.006.
* Torchalla I, Li K, Strehlau V, Linden IA, Krausz M. Religious participation and substance use behaviors in a Canadian sample of homeless people. Community Ment Health J. 2014;50(7):862–9.
* Torchalla I, Strehlau V, Li K, Krausz M. Substance use and predictors of substance dependence in homeless women. Drug Alcohol Depend. 2011;118(2–3):173–9. Available from: https://doi.org/10.1016/j.drugalcdep.2011.03.016.
* Torchalla I, Strehlau V, Okoli CTC, Li K, Schuetz C, Krausz M. Smoking and predictors of nicotine dependence in a homeless population. Nicotine Tob Res. 2011;13(10):934–42.
* Sarajlija M, Jugović A, Živaljević D, Merdović B, Sarajlija A. Assessment of health status and quality of life of homeless persons in Belgrade, Serbia. Vojnosanit Pregl. 2014;71(2):167–74.
* Harris T, Winetrobe H, Rhoades H, Wenzel S. The role of mental health and substance use in homeless adults’ tobacco use and cessation attempts. J Dual Diagn. 2019;15(2):76–87. Available from: https://doi.org/10.1080/15504263.2019.1579947.
* Skyers N, Jarrett S, McFarland W, Cole D, Atkinson U. HIV risk and gender in Jamaica’s homeless population. AIDS Behav. 2018;22(s1):65–9. Available from: https://doi.org/10.1007/s10461-018-2096-3.
* Warheit GJ, Biafora F. Mental health and substance abuse patterns among a sample of homeless post-adolescents. Int J Adolesc Youth. 1991;3(1–2):9–27.
* Zanis DA, Cohen E, Meyers K, Cnaan RA. HIV risks among homeless men differentiated by cocaine use and psychiatric distress. Addict Behav. 1997;22(2):287–92.
* Nyamathi AM, Dixon EL, Robbins W, Smith C, Wiley D, Leake B, et al. Risk factors for hepatitis C virus infection among homeless adults. J Gen Intern Med. 2002;17:134–43.
* Giannetti V, Freyder P. HIV risk among the homeless. J Health Soc Policy. 1998;10(2):27–38.
* Hwang SW, Bugeja AL. Barriers to appropriate diabetes management among homeless people in Toronto. CMAJ. 2000;163(2):161–5.
* Nower L, Eyrich-Garg KM, Pollio DE, North CS. Problem gambling and homelessness: results from an epidemiologic study. J Gambl Stud. 2015;31(2):533–45. Available from: https://doi.org/10.1007/s10899-013-9435-0.
* Ayvaci ER, Obiri O, Pollio D, North CS. A naturalistic longitudinal study of the order of service provision with respect to cocaine use and outcomes in an urban homeless sample. Epidemiol Psychiatr Sci. 2018;27(6):611–8.
* Shakarishvili A, Dubovskaya LK, Zohrabyan LS, St Lawrence JS, Aral SO, Dugasheva LG, et al. Sex work, drug use, HIV infection, and spread of sexually transmitted infections in Moscow, Russian Federation. Lancet. 2005;366(9479):57–60.
* Nyamathi AM, Dixon EL, Wiley D, Christiani A, Lowe A. Hepatitis C virus infection among homeless men referred from a community clinic. West J Nurs Res. 2006;28(4):475–88.
* Lee TC, Hanlon JG, Ben-David J, Booth GL, Cantor WJ, Connelly PW, et al. Risk factors for cardiovascular disease in homeless adults. Circulation. 2005;111(20):2629–35.
* Gelberg L, Robertson MJ, Arangua L, Leake BD, Sumner G, Moe A, et al. Prevalence, distribution, and correlates of hepatitis C virus infection among homeless adults in Los Angeles. Public Health Rep. 2012;127(4):407–21.
* Fuster D, Gelberg L. Community screening, identification, and referral to primary care, for hepatitis C, B, and HIV among homeless persons in Los Angeles. J Community Health. 2019;44(6):1044–54. Available from: https://doi.org/10.1007/s10900-019-00679-w.
* Reitzel LR, Nguyen N, Eischen S, Thomas J, Okuyemi KS. Is smoking cessation associated with worse comorbid substance use outcomes among homeless adults?. Addiction. 2014;109(12):2098–104.
* Parker RD, Dykema S. Differences in risk behaviors, care utilization, and comorbidities in homeless persons based on HIV status. J Assoc Nurses AIDS Care. 2014;25(3):214–23. Available from: https://doi.org/10.1016/j.jana.2013.06.004.
* Rhoades H, Wenzel SL, Golinelli D, Tucker JS, Kennedy DP, Green HD, et al. The social context of homeless men’s substance use. Drug Alcohol Depend. 2011;118(2–3):320–5. Available from: https://doi.org/10.1016/j.drugalcdep.2011.04.011.
* Strehlow AJ, Robertson MJ, Zerger S, Rongey C, Arangua L, Farrell E, et al. Hepatitis C among clients of health care for the homeless primary care clinics. J Health Care Poor Underserved. 2012;23(2):811–33.
* Weber M, Thompson L, Schmiege SJ, Peifer K, Farrell E. Perception of access to health care by homeless individuals seeking services at a day shelter. Arch Psychiatr Nurs. 2013;27(4):179–84. Available from: https://doi.org/10.1016/j.apnu.2013.05.001.
* Lee WG, Wong LL, Olivas R, Apana A, Kickertz K, Ogihara M. Should a homeless person become a deceased organ donor?. Clin Transplant. 2019;33(10):1–7.
* Vrouwe SQ, Johnson MB, Pham CH, Lane CJ, Garner WL, Justin Gillenwater T, et al. The homelessness crisis and burn injuries: a cohort study. J Burn Care Res. 2020;41(4):820–7.
* Alexander AC, Waring JJC, Olurotimi O, Kurien J, Noble B, Businelle MS, et al. The relations between discrimination, stressful life events, and substance use among adults experiencing homelessness. Stress Health. 2021;38(1):79–89.
* Guillén AI, Marín C, Panadero S, Vázquez JJ. Substance use, stressful life events and mental health: a longitudinal study among homeless women in Madrid (Spain). Addict Behav. 2020;103(November 2019):106246. Available from: https://doi.org/10.1016/j.addbeh.2019.106246.
* Garcia-Garcia G, Gutiérrez-Padilla AJ, Renoirte-Lopez K, Mendoza-Garcia M, Oseguera-Vizcaino MC, Perez-Gomez HR, et al. Chronic kidney disease in homeless persons in Mexico. Kidney Int Suppl. 2013;3(2):250–3.
* Childress S, Reitzel LR, Maria DS, Kendzor DE, Moisiuc A, Businelle MS. Mental Illness and substance use problems in relation to homelessness onset. Am J Health Behav. 2015;39(4):549–55.
* Chen JS, Nguyen AH, Malesker MA, Morrow LE. High-risk smoking behaviors and barriers to smoking cessation among homeless individuals. Respir Care. 2016;61(5):640–5.
* Raven MC, Kaplan LM, Rosenberg M, Tieu L, Guzman D, Kushel M. Mobile phone, computer, and internet use among older homeless adults: results from the HOPE HOME cohort study. JMIR mHealth uHealth. 2018;6(12):1–15. https://doi.org/10.2196/10049.
* Abbs E, Brown R, Guzman D, Kaplan L, Kushel M. Risk factors for falls in older adults experiencing homelessness: results from the HOPE HOME cohort study. J Gen Intern Med. 2020;35(6):1813–20.
* Garcia-Grossman I, Kaplan L, Valle K, Guzman D, Williams B, Kushel M. Factors associated with incarceration in older adults experiencing homelessness: results from the HOPE HOME study. J Gen Intern Med. 2021;37(5):1088–96. https://doi.org/10.1007/s11606-021-06897-0.
* Zlotnick C, Robertson MJ, Tam T. Substance use and labor force participation among homeless adults. Am J Drug Alcohol Abuse. 2002;28(1):37–53.
* Manhapra A, Stefanovics E, Rosenheck R. The association of opioid use disorder and homelessness nationally in the veterans health administration. Drug Alcohol Depend. 2021;223(March):108714. Available from: https://doi.org/10.1016/j.drugalcdep.2021.108714.
* Breakey WR, Fischer PJ, Kramer M, Nestadt G, Romanoski AJ, Ross A, et al. Health and mental health problems of homeless men and women in Baltimore. JAMA. 1989;262(10):1352–7.
* Smith EM, North CS, Spitznagel EL. Alcohol, drugs, and psychiatric comorbidity among homeless women: an epidemiologic study. J Clin Psychiatry. 1993;54(3):82–7.
* Muñoz M, Koegel P, Vázquez C, Sanz J, Burnam A. An empirical comparison of substance and alcohol dependence patterns in the homeless in Madrid (Spain) and Los Angeles (CA, USA). Soc Psychiatry Psychiatr Epidemiol. 2002;37(6):289–98.
* Bassuk EL, Buckner JC, Perloff JN, Bassuk SS. Among homeless and low-income housed mothers. Psychiatry Interpers Biol Process. 1998;155(11):1561–4. https://doi.org/10.1176/ajp.155.11.1561.
* Vázquez C, Muñoz M, Sanz J. Lifetime and 12-month prevalence of DSM-III-R mental disorders among the homeless in Madrid: a European study using the CIDI. Acta Psychiatr Scand. 1997;95(6):523–30.
* Beijer U, Andréasson S. Gender, hospitalization and mental disorders among homeless people compared with the general population in Stockholm. Eur J Public Health. 2010;20(5):511–6.
* Fuehrlein BS, Cowell AJ, Pollio DE, Cupps LY, Balfour ME, North CS. Deriving costs of service use among an urban homeless population. J Subst Abuse Treat. 2013;46(4):491–7. Available from: https://doi.org/10.1016/j.jsat.2013.12.002.
* Nielsen SF, Hjorthøj CR, Erlangsen A, Nordentoft M. Psychiatric disorders and mortality among people in homeless shelters in Denmark: a nationwide register-based cohort study. Lancet. 2011;377(9784):2205–14.
* Connolly AJ, Cobb-richardson P, Ball SA. Drop-in center clients. J Pers Disord. 2008;22(6):573–88.
Author information
Authors and Affiliations
Contributions
Conceptualization: Gabriela R. Perez, Carol S. North; literature search: Gabriela R. Perez, Ala Ustyol; data collection and organization: Gabriela R. Perez, Ala Ustyol, Katherine J. Mills, Josh M. Raitt; writing—original draft preparation: Gabriela R. Perez, Ala Ustyol, Carol S. North; writing–review and editing: Gabriela R. Perez, Ala Ustyol, Josh M. Raitt, Carol S. North; supervision: Carol S. North.
Corresponding author
Ethics declarations
Competing Interests
The authors have no financial or non-financial conflicts of interest to disclose.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This article is part of the Topical Collection on Social Determinants of Health
Supplementary Information
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Perez, G.R., Ustyol, A., Mills, K.J. et al. The Prevalence of Cocaine Use in Homeless Populations: A Systematic Review. Curr Treat Options Psych 9, 246–279 (2022). https://doi.org/10.1007/s40501-022-00271-5
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s40501-022-00271-5