Advertisement

Controlling interfacial mixing zone for microfluidic flow of liquid streams

  • Paritosh Agnihotri
  • V. N. Lad
Technical Paper
  • 95 Downloads

Abstract

Controlling the position and dimension of interfacial mixing width within microchannels helps in variety of applications ranging from anti-solvent crystallization to precisely locating the chemical reaction in microchannels, selective separation by convective transport, synthesis of mono-dispersed nanoparticles, reducing the transport resistance in microfluidic fuel cells, optofluidic lenses, etc. This is a big challenge especially while dealing with the miscible liquid streams. Here, we show the variation of the interfacial mixing width for two miscible liquid streams flowing in microchannels. Dynamics of mixing of the liquid streams has been studied in the near vicinity of the junction in the microchannels of different aspect ratios. We found that the convective mixing inside the microchannel is very much dependent on the relative flow rates of the streams and their Reynolds numbers. Interdiffusion mixing width decreased with increasing Reynolds number at any specific point in the direction downstream to the junction. The relative flow rates and Reynolds number of the streams have been found as influencing factors controlling the position of the interface in the microfluidic flow of liquid streams in co-laminar flow.

Keywords

Co-laminar flow Hydrodynamic flow control Interdiffsional mixing length Interfacial mixing width Microfluidic mixing 

Notes

Acknowledgments

Authors are thankful to Sardar Vallabhbhai National Institute of Technology - Surat for providing infrastructure and support through Institute Research Grant.

References

  1. 1.
    Sackmann EK, Fulton AL, Beebe DJ (2014) The present and future role of microfluidics in biomedical research. Nature 507:181–189CrossRefGoogle Scholar
  2. 2.
    Bai Y, He X, Liu D, Patil SN, Bratton D, Huebner A, Hollfelder F, Abell C, Huck WTS (2010) A double droplet trap system for studying mass transport across a droplet-droplet interface. Lab Chip 10:1281–1285CrossRefGoogle Scholar
  3. 3.
    Xu J, Ahn B, Lee H, Xu L, Lee K, Panchapakesan R, Oh KW (2012) Droplet-based microfluidic device for multiple-droplet clustering. Lab Chip 12:725–730CrossRefGoogle Scholar
  4. 4.
    Deng N-N, Wang W, Ju X-J, Xie R, Chu L-Y (2016) Spontaneous transfer of droplets across microfluidic laminar interfaces. Lab Chip 16:4326–4332CrossRefGoogle Scholar
  5. 5.
    Li X, Brooks JC, Hu J, Ford KI, Easley CJ (2017) 3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling. Lab Chip 17:341–349CrossRefGoogle Scholar
  6. 6.
    Kumar V, Paraschivoiu M, Nigam KDP (2011) Single-phase fluid flow and mixing in microchannels. Chem Eng Sci 66:1329–1373CrossRefGoogle Scholar
  7. 7.
    Zhao Y, Chen G, Yuan Q (2006) Liquid-liquid two-phase flow patterns in a rectangular microchannel. AIChE J 52:4052–4060CrossRefGoogle Scholar
  8. 8.
    Atencia J, Beebe DJ (2005) Controlled microfluidic interfaces. Nature 437:648–655CrossRefGoogle Scholar
  9. 9.
    Wu C, Tang K, Gu B, Deng J, Liu Z, Wu Z (2016) Concentration-dependent viscous mixing in microfluidics: modelings and experiments. Microfluid Nanofluidics 20:90CrossRefGoogle Scholar
  10. 10.
    Laffite G, Leroy C, Bonhomme C, Bonhomme-Coury L, Letavernier E, Daudon M, Frochot V, Haymann JP, Rouziere S, Lucas IT, Bazin D, Babonneau F, Abou-Hassan A (2016) Calcium oxalate precipitation by diffusion using laminar microfluidics: toward a biomimetic model of pathological microcalcifications. Lab Chip 16:1157–1160CrossRefGoogle Scholar
  11. 11.
    Nguyen NT, Wu Z (2005) Micromixers—a review. J Micromech Microeng 15:R1CrossRefGoogle Scholar
  12. 12.
    You JB, Kang K, Tran TT, Park H, Hwang WR, Kim JM, Im SG (2015) PDMS-based turbulent microfluidic mixer. Lab Chip 15:1727–1735CrossRefGoogle Scholar
  13. 13.
    Xia Y, Whitesides GM (1998) Soft Lithography. Annu Rev Mater Sci 28:153–184CrossRefGoogle Scholar
  14. 14.
    Lambole A, Lad VN (2017) Promising soft coating material for protection of foldable substrates exposed to corrosive environment. J Inorg Organomet Polym Mater 27:1090–1099CrossRefGoogle Scholar
  15. 15.
    Lad VN, Ralekar S (2016) Controlled evacuation using the biocompatible and energy efficient microfluidic ejector. Biomed Microdevices 18:96CrossRefGoogle Scholar
  16. 16.
    Dambrine J, Géraud B, Salmon J-B (2009) Interdiffusion of liquids of different viscosities in a microchannel. N J Phys 11:75015CrossRefGoogle Scholar
  17. 17.
    Choban ER, Markoski LJ, Wieckowski A, Kenis PJA (2004) Microfluidic fuel cell based on laminar flow. J Power Sources 128:54–60CrossRefGoogle Scholar
  18. 18.
    Whitesides GM (2006) The origins and the future of microfluidics. Nature 442:368–373CrossRefGoogle Scholar
  19. 19.
    Kjeang E, Djilali N, Sinton D (2009) Microfluidic fuel cells: a review. J Power Sources 186:353–369CrossRefGoogle Scholar
  20. 20.
    Salmon J-B, Ajdari A, Tabeling P, Servant L, Talaga D, Joanicot M (2005) In situ Raman imaging of interdiffusion in a microchannel. Appl Phys Lett 86:94106CrossRefGoogle Scholar
  21. 21.
    Ismagilov RF, Stroock AD, Kenis PJA, Whitesides G, Stone HA (2000) Experimental and theoretical scaling laws for transverse diffusive broadening in two-phase laminar flows in microchannels. Appl Phys Lett 76:2376–2378CrossRefGoogle Scholar

Copyright information

© The Brazilian Society of Mechanical Sciences and Engineering 2018

Authors and Affiliations

  1. 1.Chemical Engineering DepartmentSardar Vallabhbhai National Institute of Technology - SuratSuratIndia

Personalised recommendations