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Cancer Pain Management in Patients with Opioid Use Disorder

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Abstract

Purpose of review

Updated cancer pain management recommendations considering the rise of opioid use disorder (OUD) and opioid overdose deaths. Few studies examine cancer pain management specific to patients with OUD. This narrative review aims to review recent literature on the topic, synthesize current recommendations, and formulate practical guidance.

Recent findings

We explored Google Scholar, PubMed, and institutional databases using keywords: cancer pain, pain management, and OUD for key literature. Themes found were multimodal cancer pain management, opioid selection, opioid and OUD stigma, and barriers to medications for opioid use disorder treatment (MOUD) in cancer pain.

Summary

There was limited evidence outside of case reports and expert consensus recommendations on cancer pain management in patients with OUD, and increasing reports of barriers to use of MOUD in interdisciplinary care. Further studies are needed on facilitators to providing interdisciplinary care, including use of MOUD, for patients with cancer pain and OUD.

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Papers of particular interest, published recently, have been highlighted as: • Of importance

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Authors and Affiliations

  1. Department of Internal Medicine, Division of Palliative & Supportive Care, University of Kentucky College of Medicine, 900 Rose St., CTW Bldg. Room 308, Lexington, KY, 40508, USA

    Katrina Nickels

  2. The Ohio State University Wexner Medical Center, James Cancer Hospital, Columbus, OH, USA

    Justin Kullgren

  3. Department of Pharmacy, UK HealthCare Albert B. Chandler Hospital, Lexington, KY, USA

    Megan T. Mitchell, Marianne Carter & Brandon Kasberg

  4. Department of Internal Medicine, Section of Palliative Care, Penn State Health, Hershey, PA, USA

    Monika Holbein

  5. Department of Primary Care & Population Health, Palliative Medicine, Stanford University, Stanford, CA, USA

    Alex Gamble

  6. Department of Internal Medicine, Division of Palliative Care, Prisma Health/ University of South Carolina, Columbia, SC, USA

    Benjamin Thompson

  7. Department of Internal Medicine, Vassar Brothers Medical Center, Poughkeepsie, NY, USA

    Astha Koolwal

  8. Department of Medicine, Palliative Care and Addiction Medicine, University of California San Francisco, San Francisco, CA, USA

    J. Janet Ho

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  1. Katrina Nickels
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Nickels, K., Kullgren, J., Mitchell, M.T. et al. Cancer Pain Management in Patients with Opioid Use Disorder. Curr Addict Rep (2024). https://doi.org/10.1007/s40429-024-00577-9

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