Current Addiction Reports

, Volume 3, Issue 4, pp 445–449

Neurobiology of Disordered Gambling

Gambling (J Derevensky, Section Editor)

DOI: 10.1007/s40429-016-0119-6

Cite this article as:
Grant, J.E. Curr Addict Rep (2016) 3: 445. doi:10.1007/s40429-016-0119-6
Part of the following topical collections:
  1. Topical Collection on Gambling



Gambling disorder affects 0.4 to 1.9 % of adults worldwide and is commonly associated with significant psychosocial dysfunction.


This article provides a concise primer on recent research examining the neurobiological underpinnings of gambling disorder.


Although impulsivity has been seen as one cognitive component underlying gambling disorder, compulsivity may be equally important to examine. Although causality remains elusive, structural and functional neuroimaging data suggest dysfunction in top-down executive control in gambling disorder. Recent twin research suggests that gambling disorder may have genetic links to both gambling and to obsessive-compulsive disorder.


Understanding the neurobiology of gambling disorder may lead to improved treatment approaches.


Gambling Cognition Neuroimaging Genetics 

Funding information

Funder NameGrant NumberFunding Note
National Institute on Drug Abuse
    National Center for Responsible Gaming
      American Foundation for Suicide Prevention
        Takeda Pharmaceuticals U.S.A.

          Copyright information

          © Springer International Publishing AG 2016

          Authors and Affiliations

          1. 1.Department of Psychiatry & Behavioral Neuroscience, Pritzker School of MedicineUniversity of ChicagoChicagoUSA

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