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Molar-incisor hypomineralisation: an updated view for aetiology 20 years later

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Abstract

Background

The term Molar–Incisor Hypomineralisation (MIH) was introduced in 2001 by Weerheijm, Jälevik and Alaluusua, and describes a defect of systemic origin that affects one to four first permanent molars, often associated with permanent incisors. In the past 20 years, this definition dictated the work regarding MIH prevalence, associated risk factors, association with dental caries, impact on quality of life, and therapeutic options.

Purpose

In this report, we offer an updated and comprehensive view of MIH centred on the patient and the tooth.

Conclusion

MIH today is globally recognized as a potential public health problem and it is not a defect of purely systemic origin but rather a condition with complex aetiology that in some instances may be the result of gene-environmental interactions.

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Authors and Affiliations

  1. Department of Morphology, Genetics, Orthodontics and Pediatric Dentistry, São Paulo State University (Unesp), Araraquara School of Dentistry, Araraquara, São Paulo, Brazil

    D. G. Bussaneli & L. Santos-Pinto

  2. Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    A. R. Vieira

  3. Basic and Clinical Research Group in Dentistry, School of Dentistry, CES University, Medellín, Colombia

    M. Restrepo

Authors
  1. D. G. Bussaneli
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  2. A. R. Vieira
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  3. L. Santos-Pinto
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  4. M. Restrepo
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Contributions

DGB and MR idealized the concept and wrote the first version of the manuscript. ARV and LS-P performed the critical evaluation and revision of the manuscript. All authors approved the final version for publication of the manuscript.

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Correspondence to M. Restrepo.

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Bussaneli, D.G., Vieira, A.R., Santos-Pinto, L. et al. Molar-incisor hypomineralisation: an updated view for aetiology 20 years later. Eur Arch Paediatr Dent 23, 193–198 (2022). https://doi.org/10.1007/s40368-021-00659-6

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  • DOI: https://doi.org/10.1007/s40368-021-00659-6

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