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Biodentine™ material characteristics and clinical applications: a 3 year literature review and update

  • Systematic Review
  • Published:
European Archives of Paediatric Dentistry Aims and scope Submit manuscript

A Correction to this article was published on 10 September 2020

A Correction to this article was published on 15 March 2018

This article has been updated

Abstract

Introduction

Biodentine™ has frequently been acknowledged in the literature as a promising material and serves as an important representative of tricalcium silicate based cements used in dentistry.

Aim

To provide an update on the physical and biological properties of Biodentine™ and to compare these properties with those of other tricalcium silicate cements namely, different variants of mineral trioxide aggregate (MTA) such as ProRoot MTA, MTA Angelus, Micro Mega MTA (MM-MTA), Retro MTA, Ortho MTA, MTA Plus, GCMTA, MTA HP and calcium enriched mixture (CEM), Endosequence and Bioaggregate™.

Study design

A comprehensive literature search for publications from November 20, 2013 to November 20, 2016 was performed by two independent reviewers on Medline (PubMed), Embase, Web of Science, CENTRAL (Cochrane), SIGLE, SciELO, Scopus, Lilacs and clinicaltrials.gov. Electronic and hand search was carried out to identify randomised control trials (RCTs), case control studies, case series, case reports, as well as in vitro and animal studies published in the English language.

Conclusions

The enhanced physical and biologic properties of Biodentine™ could be attributed to the presence of finer particle size, use of zirconium oxide as radiopacifier, purity of tricalcium silicate, absence of dicalcium silicate, and the addition of calcium chloride and hydrosoluble polymer. Furthermore, as Biodentine™ overcomes the major drawbacks of MTA it has great potential to revolutionise the different treatment modalities in paediatric dentistry and endodontics especially after traumatic injuries. Nevertheless, high quality long-term clinical studies are required to facilitate definitive conclusions.

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Change history

  • 15 March 2018

    Owing to a misunderstanding on the part of the authors, the name of the last author, Prof. R. M. H. Verbeeck, was omitted from this article.

  • 10 September 2020

    A Correction to this paper has been published: https://doi.org/10.1007/s40368-020-00553-7

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The authors declare that no funding was received for this review.

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Author notes

  1. Shared first authorship; S. Rajasekharan, L. C. Martens, R. G. E. C. Cauwels and R. P. Anthonappa contributed equally to this work.

Authors and Affiliations

  1. Department of Paediatric Dentistry and special care, PAECOMEDIS Research Cluster, Ghent University, 9000, Ghent, Belgium

    S. Rajasekharan, L. C. Martens & R. G. E. C. Cauwels

  2. Paediatric Oral Health Research Group, School of Dentistry, The University of Western Australia, Perth, Australia

    R. P. Anthonappa

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  1. S. Rajasekharan
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  2. L. C. Martens
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  3. R. G. E. C. Cauwels
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  4. R. P. Anthonappa
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Correspondence to S. Rajasekharan.

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Conflict of interest

The research group received material support from Septodont, Paris, France for educational programmes intended for general dentists.

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A correction to this article is available online at https://doi.org/10.1007/s40368-018-0335-y.

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Rajasekharan, S., Martens, L.C., Cauwels, R.G.E.C. et al. Biodentine™ material characteristics and clinical applications: a 3 year literature review and update. Eur Arch Paediatr Dent 19, 1–22 (2018). https://doi.org/10.1007/s40368-018-0328-x

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