Computational and Applied Mathematics

, Volume 37, Issue 5, pp 6903–6919 | Cite as

Validation of a fractional model for erythrocyte sedimentation rate

  • J. Vanterler da C. SousaEmail author
  • Magun N. N. dos Santos
  • L. A. Magna
  • E. Capelas de Oliveira


We present the validation of a recent fractional mathematical model for erythrocyte sedimentation proposed by Sousa et al. (AIMS Math 2(4):692–705, 2017). The model uses a Caputo fractional derivative to build a time-fractional diffusion equation suitable to predict blood sedimentation rates. This validation was carried out by means of erythrocyte sedimentation tests in laboratory. Data on sedimentation rates (percentages) were analyzed and compared with the analytical solution of the time-fractional diffusion equation. The behavior of the analytical solution related to each blood sample sedimentation data was described and analyzed.


Clinical laboratory tests Erythrocyte sedimentation rate Fractional calculus Time-fractional diffusion equation 

Mathematics Subject Classification

26A06 26A33 33RXX 34A30 35KXX 92BXX 92DXX 



We would like to thank the referees for the suggestions and corrections that have improved the paper and making it more readable. We would like to thank Dr. J. Emilio Maiorino for several suggestions and comments that helped improve the paper.


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Copyright information

© SBMAC - Sociedade Brasileira de Matemática Aplicada e Computacional 2018

Authors and Affiliations

  • J. Vanterler da C. Sousa
    • 1
    Email author
  • Magun N. N. dos Santos
    • 2
    • 3
  • L. A. Magna
    • 1
    • 2
    • 3
  • E. Capelas de Oliveira
    • 1
  1. 1.Department of Applied MathematicsImecc-UnicampCampinasBrazil
  2. 2.Department of Clinical Pathology, School of Medical SciencesUnicampCampinasBrazil
  3. 3.Department of Medical Genetics, School of Medical SciencesUnicampCampinasBrazil

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