Abstracts from the 16th National Congress of the Italian Society of Cardiovascular Prevention (SIPREC), Naples, 8–10 March 2018
IS ANTIHYPERTENSIVE THERAPY WITH THIAZIDES DIURETICS IN POSTMENOPAUSAL WOMEN A RISK FACTOR FOR RUINOUS SPINAL OSTEOPOROSIS? A CASE-CONTROL STUDY
Renato De Vecchis1, Carmelina Ariano1,2, Giuseppina Di Biase3
1Cardiology Unit, Presidio Sanitario Intermedio “Elena d’Aosta”, and DSB 29 (previously “S.Gennaro dei Poveri” Hospital), Naples, Italy; 2Division of Geriatrics, Casa di Cura “Sollievo della Sofferenza”, San Giovanni Rotondo, Italy; 3Division of Geriatrics, Neurorehabilitation Unit, Clinic “S. Maria del Pozzo”, Somma Vesuviana, Italy
Introduction: A relatively recent prospective cohort study (Am J Med. 2016 Dec; 129(12): 1299–1306) has documented a relationship between chronic use of thiazide diuretics and increased risk of osteoporotic vertebral fractures. However, the thesis that thiazide diuretics exercise a beneficial effect on osteoporosis is still a predominant view.
Aim:To clarify further whether regular use of thiazide diuretics as antihypertensive therapy is associated...