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Effects of Follicular and Luteal Phase-Based Menstrual Cycle Resistance Training on Muscle Strength and Mass

Sports Medicine (2022)Cite this article

Abstract

There is an increasing interest in female athletic performance—especially concerning the impact of the female menstrual cycle on training response. Indeed, fluctuations in female sex hormones, estrogen and progesterone, during the menstrual cycle regulate protein metabolism and recovery processes in skeletal muscle and may thus impact exercise training-related outcomes. Studies demonstrate that anaerobic capacity and muscle strength are greatest during the follicular phase of the menstrual cycle, when estrogen levels peak. In addition, studies indicate that resistance training conducted in the follicular phase of the menstrual cycle (follicular phase-based resistance training) may be superior to luteal phase-based training in terms of enhancing muscle strength and mass. This raises the possibility that the physiological capabilities of skeletal muscle to adapt to exercise training are dependent on the menstrual cycle and can be important for female athletes in optimizing their training. In this paper, we critically review the current state of the art concerning the impact of menstrual cycle phase-based resistance training and highlight why follicular phase-based resistance training possibly is superior to luteal phase-based training in enhancing resistance training outcomes. Finally, we identify directions for further research.

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Author notes

  1. Julie Kissow and Kamine J. Jacobsen contributed equally.

Authors and Affiliations

  1. The August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, August Krogh Building 2nd floor, Universitetsparken 13, 2100, Copenhagen, Denmark

    Julie Kissow, Kamine J. Jacobsen, Thomas P. Gunnarsson, Søren Jessen & Morten Hostrup

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Correspondence to Morten Hostrup.

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Funding

The review was supported as part of the Novo Nordisk Foundation grant to Team Danmark on the research network “Training strategies and competition preparation.”

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Julie Kissow, Kamine J. Jacobsen, Thomas P. Gunnarsson, Søren Jessen, and Morten Hostrup declare no conflicts of interest relevant to the content of this article.

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JK and KJJ wrote the first draft of the manuscript. TPG was involved in overall feedback on the manuscript. MH and SJ critically revised the original manuscript and provided intellectual feedback. All authors read and approved the final manuscript.

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Kissow, J., Jacobsen, K.J., Gunnarsson, T.P. et al. Effects of Follicular and Luteal Phase-Based Menstrual Cycle Resistance Training on Muscle Strength and Mass. Sports Med (2022). https://doi.org/10.1007/s40279-022-01679-y

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  • DOI: https://doi.org/10.1007/s40279-022-01679-y