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Association Between Muscular Strength and Bone Health from Children to Young Adults: A Systematic Review and Meta-analysis

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Abstract

Background

Osteoporosis is a major worldwide health concern. The acquisition of bone mass during growth decreases the risk of osteoporosis later in life. Muscular strength is an important and modifiable factor to improve bone development in this period.

Objective

The aim of this review was to summarize the relationship between muscular strength and bone health.

Methods

Cross-sectional data from studies addressing this association from childhood to young adulthood were systematically searched. The DerSimonian and Laird method was used to compute pooled estimates of effect size and respective 95% CI. The meta-analyses were conducted separately for upper limbs or lower limbs muscular strength and for bone regions. Additionally, a regression model was used to estimate the influence of determinants such as age, lean mass, fat mass, height, weight and cardiorespiratory fitness in this association.

Results

Thirty-nine published studies were included in the systematic review. The pooled effect size for the association of upper limbs muscular strength with upper limbs, spine and total body BMD ranged from 0.70 to 1.07 and with upper limbs, spine and total body BMC ranged from 1.84 to 1.30. The pooled effect size for the association of lower limbs muscular strength with lower limbs, spine and total body BMD ranged from 0.54 to 0.88 and with lower limbs, spine and total body BMC ranged between 0.81 and 0.71. All reported pooled effect size estimates were statistically significant.

Conclusion

This systematic review and meta-analysis supports that muscular strength should be considered as a useful skeletal health marker during development and a target outcome for interventions aimed at improving bone health.

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Data Availability Statement

The data that support the findings of this review are available on reasonable request from the corresponding author (Vicente Martínez-Vizcaíno).

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Authors and Affiliations

  1. Faculty of Physiotherapy and Nursing, Universidad de Castilla-La Mancha, Toledo, Spain

    Ana Torres-Costoso & Purificación López-Muñoz

  2. Health and Social Research Center (CESS), Universidad de Castilla-La Mancha, Ed/ Melchor Cano, C/Santa Teresa Jornet s/n, 16071, Cuenca, Spain

    Vicente Martínez-Vizcaíno, Celia Álvarez-Bueno & Iván Cavero-Redondo

  3. Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, Chile

    Vicente Martínez-Vizcaíno

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  1. Ana Torres-Costoso
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Correspondence to Vicente Martínez-Vizcaíno.

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Ana Torres-Costoso, Purificación López-Muñoz, Celia Alvarez-Bueno, Iván Cavero-Redondo and Vicente Martínez-Vizcaíno declare that they have no conflict of interest.

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Torres-Costoso, A., López-Muñoz, P., Martínez-Vizcaíno, V. et al. Association Between Muscular Strength and Bone Health from Children to Young Adults: A Systematic Review and Meta-analysis. Sports Med 50, 1163–1190 (2020). https://doi.org/10.1007/s40279-020-01267-y

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