Marwick TH, Hordern MD, Miller T, et al. Exercise training for type 2 diabetes mellitus: impact on cardiovascular risk: a scientific statement from the American Heart Association. Circulation. 2009;119(25):3244–62. doi:10.1161/CIRCULATIONAHA.109.192521.
Article
PubMed
Google Scholar
Services UDoHaH. Physical Activity Guidelines for Americans 2008. http://www.health.gov/paguidelines/pdf/paguide.pdf. Accessed Aug 2012.
Albright A, Franz M, Hornsby G, et al. American College of Sports Medicine position stand. Exercise and type 2 diabetes. Med Sci Sports Exerc. 2000;32(7):1345–60.
CAS
Article
PubMed
Google Scholar
Haskell WL, Lee I-M, Pate RR, et al. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007;39(8):1423–34.
Article
PubMed
Google Scholar
Garber CE, Blissmer B, Deschenes MR, et al. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc. 2011;43(7):1334–59.
Article
PubMed
Google Scholar
Colberg SR, Sigal RJ, Fernhall B, et al. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes Care. 2010;33(12):e147–67. doi:10.2337/dc10-9990.
Article
PubMed
PubMed Central
Google Scholar
Artero EG, Lee DC, Lavie CJ, et al. Effects of muscular strength on cardiovascular risk factors and prognosis. J Cardiopulm Rehabil Prev. 2012;32(6):351–8. doi:10.1097/HCR.0b013e3182642688.
Article
PubMed
PubMed Central
Google Scholar
Boule NG, Kenny GP, Haddad E, et al. Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus. Diabetologia. 2003;46(8):1071–81. doi:10.1007/s00125-003-1160-2.
CAS
Article
PubMed
Google Scholar
Boule NG, Haddad E, Kenny GP, et al. Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. JAMA. 2001;286(10):1218–27.
CAS
Article
PubMed
Google Scholar
Ismail I, Keating SE, Baker MK, et al. A systematic review and meta-analysis of the effect of aerobic vs. resistance exercise training on visceral fat. Obes Rev. 2012;13(1):68–91. doi:10.1111/j.1467-789X.2011.00931.x.
CAS
Article
PubMed
Google Scholar
Vuori IM, Lavie CJ, Blair SN. Physical activity promotion in the health care system. Mayo Clin Proc. 2013;88(12):1446–61.
Article
PubMed
Google Scholar
Centers for Disease Control and Prevention. National diabetes statistics report: estimates of diabetes and its burden in the United States, 2014. Atlanta: U.S. Department of Health and Human Services, CDC; 2014.
Google Scholar
US Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, 2011. Atlanta: US Department of Health and Human Services, CDC; 2011.
Google Scholar
Rana JS, Li TY, Manson JE, et al. Adiposity compared with physical inactivity and risk of type 2 diabetes in women. Diabetes Care. 2007;30(1):53–8. doi:10.2337/dc06-1456.
Article
PubMed
Google Scholar
Church TS, Cheng YJ, Earnest CP, et al. Exercise capacity and body composition as predictors of mortality among men with diabetes. Diabetes Care. 2004;27(1):83–8.
Article
PubMed
Google Scholar
Church TS, LaMonte MJ, Barlow CE, et al. Cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes. Arch Intern Med. 2005;165(18):2114–20. doi:10.1001/archinte.165.18.2114.
CAS
Article
PubMed
Google Scholar
Program The Diabetes Prevention. (DPP): description of lifestyle intervention. Diabetes Care. 2002;25(12):2165–71.
Article
Google Scholar
Knowler WC, Fowler SE, Hamman RF, et al. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet. 2009;374(9702):1677–86. doi:10.1016/S0140-6736(09)61457-4.
Article
PubMed
Google Scholar
Donnelly JE, Blair SN, Jakicic JM, et al. American College of Sports Medicine position stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2009;41(2):459–71. doi:10.1249/MSS.0b013e3181949333.
Article
PubMed
Google Scholar
Church TS, Blair SN, Cocreham S, et al. Effects of aerobic and resistance training on hemoglobin A1c levels in patients with type 2 diabetes: a randomized controlled trial. JAMA. 2010;304(20):2253–62. doi:10.1001/jama.2010.1710.
CAS
Article
PubMed
PubMed Central
Google Scholar
Sigal RJ, Kenny GP, Boule NG, et al. Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial. Ann Intern Med. 2007;147(6):357–69.
Article
PubMed
Google Scholar
Bateman LA, Slentz CA, Willis LH, et al. Comparison of aerobic versus resistance exercise training effects on metabolic syndrome (from the Studies of a Targeted risk reduction intervention through defined exercise—STRRIDE-AT/RT). Am J Cardiol. 2011;108(6):838–44. doi:10.1016/j.amjcard.2011.04.037.
Article
PubMed
PubMed Central
Google Scholar
Balducci S, Zanuso S, Nicolucci A, et al. Effect of an intensive exercise intervention strategy on modifiable cardiovascular risk factors in subjects with type 2 diabetes mellitus: a randomized controlled trial: the Italian Diabetes and Exercise Study (IDES). Arch Intern Med. 2010;170(20):1794–803. doi:10.1001/archinternmed.2010.380.
Article
PubMed
Google Scholar
Slentz CA, Bateman LA, Willis LH, et al. Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT. Am J Physiol Endocrinol Metab. 2011;301(5):E1033–9. doi:10.1152/ajpendo.00291.2011.
CAS
Article
PubMed
PubMed Central
Google Scholar
AbouAssi H, Slentz CA, Mikus CR, et al. The effects of aerobic, resistance, and combination training on insulin sensitivity and secretion in overweight adults from STRRIDE AT/RT: a randomized trial. J Appl Physiol (1985). 2015;118(12):1474–82. doi:10.1152/japplphysiol.00509.2014.
CAS
Article
Google Scholar
Cuff DJ, Meneilly GS, Martin A, et al. Effective exercise modality to reduce insulin resistance in women with type 2 diabetes. Diabetes Care. 2003;26(11):2977–82.
Article
PubMed
Google Scholar
Hawley JA, Hargreaves M, Joyner MJ, et al. Integrative biology of exercise. Cell. 2014;159(4):738–49. doi:10.1016/j.cell.2014.10.029.
CAS
Article
PubMed
Google Scholar
Sanchez AM, Bernardi H, Py G, et al. Autophagy is essential to support skeletal muscle plasticity in response to endurance exercise. Am J Physiol Regul Integr Comp Physiol. 2014;307(8):R956–69. doi:10.1152/ajpregu.00187.2014.
CAS
Article
PubMed
Google Scholar
Koves TR, Ussher JR, Noland RC, et al. Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metabolism. 2008;7(1):45–56. doi:10.1016/j.cmet.2007.10.013.
CAS
Article
PubMed
Google Scholar
Szendroedi J, Yoshimura T, Phielix E, et al. Role of diacylglycerol activation of PKCtheta in lipid-induced muscle insulin resistance in humans. Proc Natl Acad Sci USA. 2014;111(26):9597–602. doi:10.1073/pnas.1409229111.
CAS
Article
PubMed
PubMed Central
Google Scholar
Shulman GI, Rothman DL, Jue T, et al. Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med. 1990;322(4):223–8. doi:10.1056/NEJM199001253220403.
CAS
Article
PubMed
Google Scholar
Hickson RC. Interference of strength development by simultaneously training for strength and endurance. Eur J Appl Physiol Occ Physiol. 1980;45(2–3):255–63.
CAS
Article
Google Scholar
Sparks LM, Johannsen NM, Church TS, et al. Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes. J Clin Endocrinol Metab. 2013;98(4):1694–702. doi:10.1210/jc.2012-3874.
CAS
Article
PubMed
PubMed Central
Google Scholar
Irving BA, Robinson MM, Nair KS. Age effect on myocellular remodeling: response to exercise and nutrition in humans. Ageing Res Rev. 2012;11(3):374–89. doi:10.1016/j.arr.2011.11.001.
CAS
Article
PubMed
Google Scholar
Irving BA, Lanza IR, Henderson GC, et al. Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age. J Clin Endocrinol Metab. 2015;100(4):1654–63. doi:10.1210/jc.2014-3081.
CAS
Article
PubMed
PubMed Central
Google Scholar
Willis LH, Slentz CA, Bateman LA, et al. Effects of aerobic and/or resistance training on body mass and fat mass in overweight or obese adults. J Appl Physiol (1985). 2012;113(12):1831–7. doi:10.1152/japplphysiol.01370.2011.
Article
Google Scholar
Lavie CJSD, Johannsen NM, Arena R, et al. Physical fitness—an often forgotten cardiovascular risk factor. J Glycomics Lipidomics. 2012;2(2):1–2. doi:10.4172/2153-0637.1000e104.
Google Scholar
Blair SN, Kohl HW 3rd, Paffenbarger RS Jr, et al. Physical fitness and all-cause mortality. A prospective study of healthy men and women. JAMA. 1989;262(17):2395–401.
CAS
Article
PubMed
Google Scholar
Swift DL, Lavie CJ, Johannsen NM, et al. Physical activity, cardiorespiratory fitness, and exercise training in primary and secondary coronary prevention. Circ J. 2013;77(2):281–92.
Article
PubMed
Google Scholar
Kodama S, Saito K, Tanaka S, et al. Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women. JAMA. 2009;301(19):2024–35. doi:10.1001/jama.2009.681.
CAS
Article
PubMed
Google Scholar
Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics—2012 update: a report from the American Heart Association. Circulation. 2012;125(1):e2–220. doi:10.1161/CIR.0b013e31823ac046.
Article
PubMed
Google Scholar
Larose J, Sigal RJ, Boule NG, et al. Effect of exercise training on physical fitness in type II diabetes mellitus. Med Sci Sports Exerc. 2010;42(8):1439–47. doi:10.1249/MSS.0b013e3181d322dd.
Article
PubMed
Google Scholar
Brownlee M, Cerami A. The biochemistry of the complications of diabetes mellitus. Annu Rev Biochem. 1981;50:385–432. doi:10.1146/annurev.bi.50.070181.002125.
CAS
Article
PubMed
Google Scholar
Solomon TP, Malin SK, Karstoft K, et al. The influence of hyperglycemia on the therapeutic effect of exercise on glycemic control in patients with type 2 diabetes mellitus. JAMA Intern Med. 2013;173(19):1834–6. doi:10.1001/jamainternmed.2013.7783.
Article
PubMed
Google Scholar
Johannsen NM, Swift DL, Lavie CJ, et al. Categorical analysis of the impact of aerobic and resistance exercise training, alone and in combination, on cardiorespiratory fitness levels in patients with type 2 diabetes mellitus: results from the HART-D study. Diabetes Care. 2013;36(10):3305–12. doi:10.2337/dc12-2194.
Article
PubMed
PubMed Central
Google Scholar
Sui X, LaMonte MJ, Blair SN. Cardiorespiratory fitness and risk of nonfatal cardiovascular disease in women and men with hypertension. Am J Hypertens. 2007;20(6):608–15. doi:10.1016/j.amjhyper.2007.01.009.
Article
PubMed
PubMed Central
Google Scholar
Gulati M, Black HR, Shaw LJ, et al. The prognostic value of a nomogram for exercise capacity in women. N Engl J Med. 2005;353(5):468–75. doi:10.1056/NEJMoa044154.
CAS
Article
PubMed
Google Scholar
Morris CK, Myers J, Froelicher VF, et al. Nomogram based on metabolic equivalents and age for assessing aerobic exercise capacity in men. J Am Coll Cardiol. 1993;22(1):175–82.
CAS
Article
PubMed
Google Scholar
Ross R, Hudson R, Stotz PJ, et al. Effects of exercise amount and intensity on abdominal obesity and glucose tolerance in obese adults: a randomized trial. Ann Intern Med. 2015;162(5):325–34. doi:10.7326/M14-1189.
Article
PubMed
Google Scholar
Wolfe RR. The underappreciated role of muscle in health and disease. Am J Clin Nutr. 2006;84(3):475–82.
CAS
PubMed
Google Scholar
Stump CS, Henriksen EJ, Wei Y, et al. The metabolic syndrome: role of skeletal muscle metabolism. Ann Med. 2006;38(6):389–402. doi:10.1080/07853890600888413.
CAS
Article
PubMed
Google Scholar
Fujita Y, Nakamura Y, Hiraoka J, et al. Physical-strength tests and mortality among visitors to health-promotion centers in Japan. J Clin Epidemiol. 1995;48(11):1349–59.
CAS
Article
PubMed
Google Scholar
Rantanen T, Harris T, Leveille SG, et al. Muscle strength and body mass index as long-term predictors of mortality in initially healthy men. J Gerontol A Biol Sci Med Sci. 2000;55(3):M168–73.
CAS
Article
PubMed
Google Scholar
Katzmarzyk PT, Craig CL. Musculoskeletal fitness and risk of mortality. Med Sci Sports Exerc. 2002;34(5):740–4.
Article
PubMed
Google Scholar
Artero EG, Lee DC, Ruiz JR, et al. A prospective study of muscular strength and all-cause mortality in men with hypertension. J Am Coll Cardiol. 2011;57(18):1831–7. doi:10.1016/j.jacc.2010.12.025.
Article
PubMed
PubMed Central
Google Scholar
Jurca R, Lamonte MJ, Barlow CE, et al. Association of muscular strength with incidence of metabolic syndrome in men. Med Sci Sport Exerc. 2005;37(11):1849–55.
Article
Google Scholar
Jurca R, Lamonte MJ, Church TS, et al. Associations of muscle strength and fitness with metabolic syndrome in men. Med Sci Sports Exerc. 2004;36(8):1301–7.
Article
PubMed
Google Scholar
Bacchi E, Negri C, Zanolin ME, et al. Metabolic effects of aerobic training and resistance training in type 2 diabetic subjects: a randomized controlled trial (the RAED2 study). Diabetes Care. 2012;35(4):676–82. doi:10.2337/dc11-1655.
CAS
Article
PubMed
PubMed Central
Google Scholar
Mason C, Brien SE, Craig CL, et al. Musculoskeletal fitness and weight gain in Canada. Med Sci Sports Exerc. 2007;39(1):38–43. doi:10.1249/01.mss.0000240325.46523.cf.
Article
PubMed
Google Scholar
Jackson AW, Lee DC, Sui X, et al. Muscular strength is inversely related to prevalence and incidence of obesity in adult men. Obesity (Silver Spring). 2010;18(10):1988–95. doi:10.1038/oby.2009.422.
Article
PubMed
Google Scholar
Wijndaele K, Duvigneaud N, Matton L, et al. Muscular strength, aerobic fitness, and metabolic syndrome risk in Flemish adults. Med Sci Sports Exerc. 2007;39(2):233–40. doi:10.1249/01.mss.0000247003.32589.a6.
Article
PubMed
Google Scholar
Newman AB, Kupelian V, Visser M, et al. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci. 2006;61(1):72–7.
Article
PubMed
Google Scholar
Wood RH, Reyes R, Welsch MA, et al. Concurrent cardiovascular and resistance training in healthy older adults. Med Sci Sports Exerc. 2001;33(10):1751–8.
CAS
Article
PubMed
Google Scholar
Pahor M, Guralnik JM, Ambrosius WT, et al. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014;311(23):2387–96. doi:10.1001/jama.2014.5616.
CAS
Article
PubMed
PubMed Central
Google Scholar
Senechal M, Swift DL, Johannsen NM, et al. Changes in body fat distribution and fitness are associated with changes in hemoglobin A1c after 9 months of exercise training: results from the HART-D study. Diabetes Care. 2013;36(9):2843–9. doi:10.2337/dc12-2428.
CAS
Article
PubMed
PubMed Central
Google Scholar
Larose J, Sigal RJ, Khandwala F, et al. Associations between physical fitness and HbA(1)(c) in type 2 diabetes mellitus. Diabetologia. 2011;54(1):93–102. doi:10.1007/s00125-010-1941-3.
CAS
Article
PubMed
Google Scholar
Swift DL, Johannsen NM, Earnest CP, et al. Effect of exercise training modality on C-reactive protein in type 2 diabetes. Med Sci Sports Exerc. 2012;44(6):1028–34. doi:10.1249/MSS.0b013e31824526cc.
CAS
Article
PubMed
PubMed Central
Google Scholar
Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30(6):473–83.
Article
PubMed
Google Scholar
Myers VH, McVay MA, Brashear MM, et al. Exercise training and quality of life in individuals with type 2 diabetes: a randomized controlled trial. Diabetes Care. 2013;36(7):1884–90. doi:10.2337/dc12-1153.
Article
PubMed
PubMed Central
Google Scholar
Reid RD, Tulloch HE, Sigal RJ, et al. Effects of aerobic exercise, resistance exercise or both, on patient-reported health status and well-being in type 2 diabetes mellitus: a randomised trial. Diabetologia. 2010;53(4):632–40. doi:10.1007/s00125-009-1631-1.
CAS
Article
PubMed
Google Scholar
Bouchard C, Blair SN, Church TS, et al. Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS One. 2012;7(5):e37887. doi:10.1371/journal.pone.0037887.
CAS
Article
PubMed
PubMed Central
Google Scholar