Abstract
Doping may be defined, broadly, as the use of unauthorised means to increase performance in sport. Doping is most commonly associated with the use of drugs. In this paper, I discuss the use of emerging techniques for the modulation of brain activity in healthy people using electric or magnetic fields, and suggest how they might be used to enhance physical and mental performance in sports. I will suggest that neurodoping may have different uses in different sports, and I argue that each sport must determine whether neurodoping should be considered as cheating, or should be considered a legitimate aid to training or performance.
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References
Wilson S, Lockwood R, Thickbroom G, Mastaglia F. The muscle silent period following transcranial magnetic cortical stimulation. J Neurol Sci. 1993;114:216–22.
Huang Y, Edwards M, Rounis E, Bhatia K, Rothwell J. Theta burst stimulation of the human motor cortex. Neuron. 2005;45:201–6.
Teneback C, Nahas Z, Speer A, Molloy M, Stallings L, Spicer K, et al. Changes in prefrontal cortex and paralimbic activity in depression following two weeks of daily left prefrontal TMS. J Neuropsychiatry Clin Neurosci. 1999;11:426–35.
Stagg CJ, Nitsche MA. Physiological basis of transcranial direct current stimulation. Neuroscientist. 2011;17(1):37–53.
Kanai R, Chaieb L, Antal A, Walsh V, Paulus W. Frequency-dependent electrical stimulation of the visual cortex. Curr Biol. 2008;18(23):1839–43.
Kanai R, Paulus W, Walsh V. Transcranial alternating current stimulation (tACS) modulates cortical excitability as assessed by TMS-induced phosphene thresholds. Clin Neurophysiol. 2010;121:1551–4.
Miranda PC, Lomarev M, Hallett M. Modeling the current distribution during transcranial direct current stimulation. Clin Neurophysiol. 2006;117(7):1623–9.
Wagner T, Zahn M, Grodzinsky A, Pascual-Leone A. Three-dimensional head model simulation of transcranial magnetic stimulation. IEEE Trans Biomed Eng. 2004;51:1586–98.
Cogiamanian F, Marceglia S, Ardolino G, Barbieri S, Priori A. Improved isometric force endurance after transcranial direct current stimulation over the human motor cortical areas. Eur J Neurosci. 2007;26(1):242–9.
Pascual-Leone A, Valls-Sole J, Wassermann E, Brasil-Neto J, Cohen L, Hallett M. Effects of focal transcranial magnetic stimulation on simple reaction time to acoustic, visual and somatosensory stimuli. Brain. 1992;115:1045–59.
Axford P, Lakany H, Conway B. The effects of transcranial stimulation on enhanced physiological tremor: a pilot study. In: 6th UKRI PG Conference in biomedical engineering and medical physics 2011. Glasgow, UK; 2011.
Nitsche M, Paulus W. Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology. 2001;57:1899–901.
Reis J, Schambra HM, Cohen LG, Buch ER, Fritsch B, Zarahn E, et al. Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation. Proc Natl Acad Sci USA. 2009;106(5):1590–5.
Vines BW, Cerruti C, Schlaug G. Dual-hemisphere tDCS facilitates greater improvements for healthy subjects’ non-dominant hand compared to uni-hemisphere stimulation. BMC Neurosci. 2008;9:103.
Stagg C, Wylezinska M, Matthews P, Johansen-Berg H, Jezzard P, Rothwell J, et al. Neurochemical effects of theta burst stimulation as assessed by magnetic resonance spectroscopy. J Neurophysiol. 2009;101:2872–7.
Stagg CJ, Best JG, Stephenson MC, O’Shea J, Wylezinska M, Kineses ZT, et al. Polarity-sensitive modulation of cortical neurotransmitters by transcranial stimulation. J Neurosci. 2009;29(16):5202–6.
Clark VP, Coffman BA, Trumbo MC, Gasparovic C. Transcranial direct current stimulation (tDCS) produces localized and specific alterations in neurochemistry: a 1H magnetic resonance spectroscopy study. Neurosci Lett. 2011;500(1):67–71.
Tharayil BS, Gangadhar BN, Thirthalli J, Anand L. Seizure with single-pulse transcranial magnetic stimulation in a 35-year-old otherwise-healthy patient with bipolar disorder. J ECT. 2005;21:188–9.
Savulescu J, Foddy B, Clayton M. Why we should allow performance enhancing drugs in sport. Brit J Sports Med. 2004;38:666–70.
Cohen Kadosh R, Levy N, O’Shea J, Shea N, Savulescu J. The neuroethics of non-invasive brain stimulation. Curr Biol. 2012;22:R108–R11.
Cohen Kadosh R. Using transcranial electrical stimulation to enhance cognitive functions in the typical and atypical brain. Transl Neurosci. 2013;4:1–14.
Tang W-T, Zhang W-Y, Huang C-C, Young M-S, Hwang I-S. Postural tremor and control of the upper limb in air pistol shooters. J Sports Sci. 2006;24:1579–87.
Magnus J, Klaassen F. On the advantage of serving first in a tennis set: four years at Wimbledon. Statistician. 1999;48:247–56.
Schermer M. On the argument that enhancement is “cheating”. J Med Ethics. 2008;34:85–8.
Stokes M, Barker A, Dervinis M, Verbruggen F, Maizey L, Adams R, et al. Biophysical determinants of transcranial magnetic stimulation: effects of excitability and depth of targeted area. J Neurophysiol. 2013;109:437–44.
Nitsche MA, Boggio PS, Fregni F, Pascual-Leone A. Treatment of depression with transcranial direct current stimulation (tDCS): a review. Exp Neurol. 2009;219(1):14–9.
Amiaz R, Levy D, Vainiger D, Grunhaus L, Zangen A. Repeated high-frequency transcranial magnetic stimulation over the dorsolateral prefrontal cortex reduces cigarette craving and consumption. Addiction. 2009;104:653–60.
Csikszentmihalyi M. Flow: the psychology of optimal experience. New York: Harper & Row; 1990.
Snyder A, Bahramali H, Hawker T, Mitchell D. Savant-like numerosity skills revealed in normal people by magnetic pulses. Perception. 2006;35:837–45.
Chi RP, Snyder AW. Facilitate insight by non-invasive brain stimulation. PLoS ONE. 2011;6(2).
Jackson S, Csikszentmihalyi M. Flow in sports: the keys to optimal experiences and performances. Champaign, IL: Human Kinetics; 1999.
Jackson S. Factors influencing the occurrence of flow state in elite athletes. J Appl Sport Psychol. 1995;7:138–66.
Fuerra M, Bianco G, Santarnecchi E, Del Testa M, Rossi A, Rossi S. Frequency-dependent tuning of the human motor system induced by transcranial oscillatory potentials. J Neurosci. 2011;31(34):12165–70.
Davis N, Tomlinson S, Morgan H. The role of beta-frequency neural oscillations in motor control. J Neurosci. 2012;32:403–4.
Pogosyan A, Gaynor L, Eusebio A, Brown P. Boosting cortical activity at beta-band fequencies slows movement in humans. Curr Biol. 2009;19:1637–41.
Terney D, Chaieb L, Moliadze V, Antal A, Paulus W. Increasing human brain excitability by transcranial high-frequency random noise stimulation. J Neurosci. 2008;28(52):14147–55.
Oliviero A, Mordillo-Mateos L, Arias P, Panyavin I, Foffani G, Aguilar J. Transcranial static magnetic field stimulation of the human motor cortex. J Physiol. 2011;589(20):4949–58.
Acknowledgements
This work was supported by the Future and Emerging Technologies (FET) programme within the Seventh Framework Programme for Research of the European Commission, under FETOpen grant number: 222079 (HIVE). I am grateful to Dr Martyn Bracewell and Mr Simon Tomlinson and two anonymous reviewers for helpful comments. I declare no conflicts of interest in preparing this article.
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Davis, N.J. Neurodoping: Brain Stimulation as a Performance-Enhancing Measure. Sports Med 43, 649–653 (2013). https://doi.org/10.1007/s40279-013-0027-z
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DOI: https://doi.org/10.1007/s40279-013-0027-z