Notes
SS is a potentially life-threatening condition, for which signs and symptoms can include mental status changes, seizures, and neuromuscular symptoms. NMS is characterised by similar symptoms to SS (e.g. altered mental status, muscular rigidity and tremor).
Melaena refers to dark black, tarry faeces that are associated with upper gastrointestinal bleeding.
Reference
Zappacosta S, et al. Inconsistent labelling for drug interactions. WHO Pharmaceuticals Newsletter : 16-7, No. 4, Aug 2018. Available from: URL: http://apps.who.int/iris/bitstream/handle/10665/274266/WPN-2018-04-eng.pdf?ua=1
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Inconsistent labelling for drug interactions in US, EU. Reactions Weekly 1718, 1 (2018). https://doi.org/10.1007/s40278-018-51345-z
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DOI: https://doi.org/10.1007/s40278-018-51345-z