Notes
EURAP = International Registry of Antiepileptic Drugs and Pregnancy
The most frequently reported MCMs were cardiac malformations, hypospadia, and neural tube defects.
Reference
Tomson T, et al. Dose-dependent teratogenicity of valproate in mono- and polytherapy: an observational study. Neurology : [7 pages], 17 Jun 2015. Available from: URL: http://doi.org/10.1212/WNL.0000000000001772
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Valproic acid: risk of congenital malformations discussed. Reactions Weekly 1559, 13 (2015). https://doi.org/10.1007/s40278-015-3202-1
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DOI: https://doi.org/10.1007/s40278-015-3202-1