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Administering remdesivir to eligible patients during a wave of COVID-19 infections may help reduce costs, according to a retrospective analysis of data from the first wave of COVID-19 in a tertiary-care hospital in Germany.
The studyFootnote 1, published in Infection, retrospectively reviewed medical charts of patients with COVID-19 treated at University Hospital Cologne, Germany, during the first wave of COVID-19 infections. Eligible patients were clustered using an eight-category ordinal scale to reflect different levels of supplemental oxygen. Potential cost savings from administering remdesivir (according to European Medicines Agency label) were modelled using retrospective length-of-stay data from the Adaptive COVID-19 Treatment Trial. A healthcare payer perspective was taken, and costs (2020 values) included those for staff, material, and infrastructure; acquisition costs of remdesivir were not included in the analysis.
In total, 105 patients with COVID-19 were included in the study. There was a large range in resource consumption with median treatment costs from around €900 to €53 000 per patient, depending on diagnostic category and clinical severity. No supplemental oxygen was needed in 40 patients (38%); 43 patients (41%) were admitted to intensive-care units, and 30 (70%) received invasive ventilation. On-label administration of remdesivir would have reduced costs by €2100 per inpatient.
Notes
This study received funding from Gilead Sciences.
Reference
Jeck J, et al. A cost of illness study of COVID-19 patients and retrospective modelling of potential cost savings when administering remdesivir during the pandemic "first wave" in a German tertiary care hospital. Infection : 1-11, 18 Aug 2021. Available from: URL: http://doi.org/10.1007/s15010-021-01685-8
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Remdesivir may be cost saving in eligible patients during COVID-19 infections in Germany. PharmacoEcon Outcomes News 886, 19 (2021). https://doi.org/10.1007/s40274-021-07997-6
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DOI: https://doi.org/10.1007/s40274-021-07997-6