Treat gestational diabetes with insulin and/or oral antidiabetic agents when lifestyle changes are not effective
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Treatment of gestational diabetes is important to achieve glycaemic control and reduce the risk of fetal and maternal complications. If nutritional therapy and/or physical activity are ineffective, treatment with insulin is usually recommended. Although metformin and glyburide (glibenclamide) are effective oral antidiabetics, their benefits and risks in treatment gestational diabetes should be carefully considered, as both agents cross the placenta and data on their long-term safety in pregnant women and fetuses are lacking.
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Conflict of interest
The article was adapted from Drugs 2017;77(16):1723–32  by employees of Adis/Springer, who are responsible for the article content and declare no conflicts of interest.
The preparation of this review was not supported by any external funding.
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