Drugs & Therapy Perspectives

, Volume 34, Issue 5, pp 203–206 | Cite as

Consider using opioids to treat restless legs syndrome in patients who have become refractory or intolerant to other treatments

  • Adis Medical Writers
Disease Management


Although initially effective in treating restless legs syndrome (RLS), some treatments, such as dopamine agonists, eventually lose efficacy and may worsen RLS symptoms. According to current evidence, opioids are effective, and may be an appropriate option for treating patients with refractory RLS or those who cannot tolerant other treatments, given that the potential risk factors involved are carefully considered.


Compliance with ethical standards

Conflict of interest

The article was adapted from Drugs 2017;77(12):1337-44 [1] by employees of Adis/Springer, who are responsible for the article content and declare no conflicts of interest.


The preparation of this review was not supported by any external funding.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.SpringerAucklandNew Zealand

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