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Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application

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Abstract

Surgical site infections are among the most common healthcare-associated infections and are linked with increased length of hospitalization, re-admission, mortality and significant financial burden. Risk factors for the occurrence of surgical site infections include variables related to the surgical procedure as well as host factors. Increasing age is associated with the occurrence of surgical site infections. The aim of this review is to give an update on the antibiotic prophylaxis for surgical site infection in elderly people. We focused on specific issues and practical applications, such as the importance of targeting the antimicrobial agent to the susceptibility pattern of colonizing flora in selected cases and the need for dosage modifications.

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Acknowledgements

Maria Adriana Cataldo and Nicola Petrosillo are active members of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Infections in the Elderly (ESGIE) and would like to thank ESGIE members for the discussions leading to this study.

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  1. Clinical Department, National Institute for Infectious Diseases “Lazzaro Spallanzani”, via Portuense 292, 00149, Rome, Italy

    Maria Adriana Cataldo, Guido Granata & Nicola Petrosillo

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  1. Maria Adriana Cataldo
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  2. Guido Granata
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Correspondence to Nicola Petrosillo.

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Maria Adriana Cataldo, Guido Granata, and Nicola Petrosillo have no conflicts of interest.

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Cataldo, M.A., Granata, G. & Petrosillo, N. Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application. Drugs Aging 34, 489–498 (2017). https://doi.org/10.1007/s40266-017-0471-9

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