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Therapeutic Strategies to Treat Dry Eye in an Aging Population

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Abstract

Dry eye (DE) is a prevalent ocular disease that primarily affects the elderly. Affecting up to 30 % of adults aged 50 years and older, DE affects both visual function and quality of life. Symptoms of DE, including ocular pain (aching, burning), visual disturbances, and tearing, can be addressed with therapeutic agents that target dysfunction of the meibomian glands, lacrimal glands, goblet cells, ocular surface, and/or neural network. This review provides an overview of the efficacy, use, and limitations of current therapeutic interventions being used to treat DE.

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Acknowledgments

This work was supported by the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Clinical Sciences Research and Development’s Career Development Award CDA-2-024-10S (Dr. Galor), National Institutes of Health Center Core Grant P30EY014801, and Research to Prevent Blindness unrestricted grant.

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Authors and Affiliations

  1. Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA

    Nisreen S. Ezuddin, Karam A. Alawa & Anat Galor

  2. Miami Veterans Administration Medical Center, 1201 NW 16th Street, Miami, FL, 33125, USA

    Anat Galor

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  1. Nisreen S. Ezuddin
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  3. Anat Galor
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Correspondence to Anat Galor.

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Nisreen S. Ezuddin, Karam A. Alawa, and Anat Galor declare no conflicts of interest.

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Ezuddin, N.S., Alawa, K.A. & Galor, A. Therapeutic Strategies to Treat Dry Eye in an Aging Population. Drugs Aging 32, 505–513 (2015). https://doi.org/10.1007/s40266-015-0277-6

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  • DOI: https://doi.org/10.1007/s40266-015-0277-6

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